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    La Jolla, CA Office Units for Lease

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    Found 369 office unit listings for lease in La Jolla, CA, averaging $23/SF/YR. Use lease type data to compare options faster.
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    Office Suite with Combination Potential
    Office Suite with Combination Potential

    3710 Ruffin Rd, San Diego, CA 92123

    Full service Serra Mesa
    Contact for pricing
    61–103 people  1 space  15,476 sqft

    Office suite space available for lease, with option to combine Suite B with Suite A for expanded occupancy.

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    Class A Office Space Available
    Class A Office Space Available

    8889 Rio, San Diego, CA 92108

    Mission Valley East
    Contact for pricing

    Two-story, 29,639 SF office space with freeway access.

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    San Diego Office Space Available
    San Diego Office Space Available

    9373 Hazard Way, San Diego, CA

    Full service Kearny Mesa
    Contact for pricing
    6–10 people  2 spaces  1,540 sqft  0.48 acres

    Office space for rent in San Diego, 3,790 SF available.

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    Two-Story Garden Office Suites
    Two-Story Garden Office Suites

    7510-7514 Clairemont Mesa Blvd, San Diego, CA 92111

    Full service Clairemont Mesa East
    Contact for pricing
    3–5 people  5 spaces  889 sqft  2-story
    Highway access

    Two-suite office setup with reception and full HVAC, offering glass-lined space and strong freeway access for daily operations.

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    24-Hour Access Office Suites
    24-Hour Access Office Suites

    3914 Murphy Canyon Rd, San Diego, CA 92123

    Full service Kearny Mesa
    Contact for pricing
    3–5 people  1 space  779 sqft
    Highway access

    Office suites with individual suite identification, conference facilities, and ample parking in a professionally managed building.

    On-Site Deli  On-Site Fitness Room  Conference Facilities  Ample Parking Available
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    Office Suites with 24-Hour Access
    Office Suites with 24-Hour Access

    3914 Murphy Canyon Rd, San Diego, CA 92123

    Full service Kearny Mesa
    Contact for pricing
    4–7 people  1 space  1,163 sqft

    Office suites offer conference facilities, on-site deli and fitness room, plus ample parking and 24-hour access.

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    Open-Layout Office Suite
    Open-Layout Office Suite

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    31–51 people  7,764 sqft

    Office suite with an open layout and double doors off the lobby corridor.

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    San Diego Office Space Available
    San Diego Office Space Available

    5333 Mission Center Rd, San Diego, CA

    Mission Valley East
    Contact for pricing
    11–18 people  2,844 sqft  7.52 acres

    Office space featuring reception, offices, breakroom, and courtyard access.

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    Garden Office Courtyard Suite
    Garden Office Courtyard Suite

    10505 Sorrento Valley Rd, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    7–12 people  1 space  1,907 sqft
    Highway access

    Garden-style courtyard office space with operable windows, showers, and a common conference room.

    Monument signage  Garden style courtyard  Common area conference room  Showers
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    High-End Office Space Available
    High-End Office Space Available

    10920 Via Frontera, San Diego, CA

    Rancho Bernardo
    Contact for pricing
    14–24 people  3,685 sqft  2.62 acres

    Top floor office space with scenic views and upgraded finishes.

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    Office/Medical Space Available
    Office/Medical Space Available

    10455 Pacific Center Court, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing

    Office and medical space for rent in San Diego.

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    Third-Floor Office Space with Natural Light
    Third-Floor Office Space with Natural Light

    1350 Columbia St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    11–18 people  1 space  2,752 sqft  Built 2007
    Public transit  Highway access

    Third-floor office with natural light, exposed HVAC, and concrete walls and ceilings in the MetroWork building.

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    Office Space for Sublease
    Office Space for Sublease

    12790 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    141–236 people  35,482 sqft
    29 private offices  5 meeting rooms

    Sublease office with 63 workstations, 29 private offices, and five conference rooms plus a break room.

    Break Room
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    Renovated San Diego Amenity-Rich Space
    Renovated San Diego Amenity-Rich Space

    8145-8245 Ronson Rd., San Diego, CA 92111

    Coworking Kearny Mesa
    Contact for pricing
    3 spaces  Built 2026

    Recently renovated office and fitness spaces with extensive amenity center.

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    Creative Office Suite with Conference Room
    Creative Office Suite with Conference Room

    2251 San Diego Ave, San Diego, CA 92110

    Full service Old Town
    Contact for pricing
    1 person  1 space  293 sqft  modern Spanish style
    Highway access

    Renovated office suite featuring six private offices and a conference room with exposed wood beams and vaulted ceilings.

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    ABC-Licensed Nightclub and Office
    ABC-Licensed Nightclub and Office

    500-502 Fourth Ave, San Diego, CA 92101

    Triple net (NNN) Marina
    Contact for pricing
    11,000 sqft  2-story

    Includes an ABC-licensed 11,000 SF nightclub plus 2,000 SF second-floor office.

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    Move-In Ready Office Suites Available
    Move-In Ready Office Suites Available

    8755-8775 Aero Dr, San Diego, CA

    Modified gross Serra Mesa
    Contact for pricing
    9–16 people  2 spaces  2,496 sqft  3.93 acres

    Office suites available for rent with flexible lease terms.

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    Office Space in Secure Location
    Office Space in Secure Location

    16705 Via Del Campo Ct, San Diego, CA

    Rancho Bernardo
    Contact for pricing
    113–188 people  28,313 sqft  11.72 acres

    Office space with high-quality construction and lab-ready features.

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    Contiguous Office Suites
    Contiguous Office Suites

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    5–9 people  1,446 sqft

    Contiguous office suites with double-door entry off the elevator lobby.

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    Renovated San Diego Office Space
    Renovated San Diego Office Space

    8250-8380 Vickers St., San Diego, CA 92111

    Kearny Mesa
    Contact for pricing
    4 spaces  Built 2026

    Recently renovated office space with modern amenities in San Diego.

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    Mesa Rim Road Office Space
    Mesa Rim Road Office Space

    9955 Mesa Rim Rd, San Diego, CA

    Sorrento Valley
    Contact for pricing
    63–105 people  15,853 sqft  5.46 acres

    Office space with private offices, conference rooms, and clean rooms.

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    Rancho Bernardo Office Space Available
    Rancho Bernardo Office Space Available

    16745 W Bernardo Dr, San Diego, CA

    Rancho Bernardo
    Contact for pricing
    52–88 people  13,232 sqft  5.31 acres

    Office space with signage and transit access in San Diego.

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    Life Science Development in San Diego
    Life Science Development in San Diego

    4242 Campus Point Court, San Diego, CA 92121

    Torrey Pines
    Contact for pricing

    High-amenity life science development in University Towne Centre.

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    Office Space For Rent
    Office Space For Rent

    5675 Ruffin Rd, San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    11–18 people  2,830 sqft

    Office space available for rent in San Diego, CA.

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    Most Searched ZIP Codes in La Jolla, CA

    • 92121
    • 92123
    • 92130
    • 92101
    • 92108
    • 92127
    • 92037
    • 92128
    • 92122
    • 92110
    • 92111
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