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Apple Valley, CA Office Space for Lease

13 results
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Apple Valley Commercial Space Available
$1,000 / Mo
750 SF

Apple Valley Commercial Space Available

16025 Kamana Rd, Apple Valley, CA 92307

Bottom floor office/commercial space in a high-traffic area.

  • High‑traffic location near Desert Community Bank and St. Mary's Hospital.
  • Suitable for professional office or medical use.
  • Bottom floor accessibility.
  • Anchored by a busy convenience store, providing potential customer base.
  • Gross rent includes water and trash.
Updated: Oct 28, 2025
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Medical Office Space Available
Contact for pricing
9,299 SF

Medical Office Space Available

15995 Tuscola Rd, Apple Valley, CA 92307

Medical office space for lease near St. Mary's Hospital.

  • Medical office space near St. Mary's Hospital
  • Convenient location just off HWY 18 in Apple Valley
  • Negotiable lease terms
  • 1095 sq. ft. office space
  • Ample parking: shared front and rear parking spaces, including handicap spaces
Updated: Dec 6, 2024
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Apple Valley Office Space Available
Contact for pricing
2,256 SF

Apple Valley Office Space Available

Newer office building with mountain views and tenant improvements.

16098 Kamana Rd, Apple Valley, CA 92307
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Apple Valley Multi-Tenant Office Space
$1.40 SF/Yr
3,840 SF

Apple Valley Multi-Tenant Office Space

Professional office suites available for lease in Apple Valley.

16048 Tuscola Rd, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
$500 / Mo
13,622 SF

Multi-Tenant Office/Retail Space Available

Two-story office/retail space in The Knolls Center.

17993 Knl Ctr, Apple Valley, CA 92307
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Apple Valley Office/Medical Space
Contact for pricing

Apple Valley Office/Medical Space

Premier office/medical building with great frontage in Apple Valley.

16008 Kamana Rd, Apple Valley, CA 92307
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Historic Apple Valley Inn Office
$1,800 / Mo
64,784 SF

Historic Apple Valley Inn Office

Unique office space in a historic landmark building.

20600 Suite 108 & 109, Apple Valley, CA 92307
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Prime Endcap Retail Unit
$1.30 SF/Yr
15,100 SF

Prime Endcap Retail Unit

Spacious retail unit in a thriving shopping center.

20162 Us Highway 18, Apple Valley, CA 92307
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Apple Valley Medical Office Space
$1.20 SF/Yr
28,929 SF

Apple Valley Medical Office Space

Well-appointed medical/professional suite in Apple Valley's medical corridor.

18523 Corwin Rd, Apple Valley, CA 92307
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Professional Office Space Available
$1,707 / Mo

Professional Office Space Available

First-generation office suite near St. Mary's Medical Center.

18270 Siskiyou Rd, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
Contact for pricing

Multi-Tenant Office/Retail Space Available

13,622 SF multi-tenant office/retail space on Highway 18.

17993 106, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
Contact for pricing

Multi-Tenant Office/Retail Space Available

Two-story office/retail space in The Knolls Center available for rent.

17993 107, Apple Valley, CA 92307
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Historic Apple Valley Office Space
$1,650 / Mo
64,784 SF

Historic Apple Valley Office Space

Unique office space in a historic landmark, Apple Valley Inn.

20600 Us Highway 18, Apple Valley, CA 92307
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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 13 Active listings in Apple Valley, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Explore Office space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Victorville Commercial Space For Lease
$1,600 / Mo
1,370 SF

Victorville Commercial Space For Lease

Commercial space in Victorville with frontage on a main road.

15040 7Th St, Victorville, CA 92395
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Victorville Professional Office Space Available
$1,100 / Mo
46,332 SF

Victorville Professional Office Space Available

Professional office space with ample parking and high visibility.

16519 Victor St, Victorville, CA 92395
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Furnished Office Space For Lease
$2,500 / Mo

Furnished Office Space For Lease

Furnished office space in Hesperia, near Victor Valley College.

12061 Jacaranda Ave, Hesperia, CA 92345
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Hesperia Office Space For Rent
$1,600 / Mo

Hesperia Office Space For Rent

Centrally located office space on Bear Valley Rd for rent.

15659 Bear Valley Rd, Hesperia, CA 92345
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Explore Similar Spaces for Sale in Apple Valley, CA

Consider Similar Space for Sale. We found 3 Spaces in Nearby Locations matching your search parameters.

Renovated Commercial Building in Apple Valley
$349,000
1,510 SF

Renovated Commercial Building in Apple Valley

Meticulously renovated commercial building with modern workspace and dynamic floor plan.

21948 Us Highway 18, Apple Valley, CA 92307
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Apple Valley Retail/Office Building
$500,000
3,750 SF

Apple Valley Retail/Office Building

Retail/office building in Apple Valley's historic district.

22573 S Outer Hwy, Apple Valley, CA
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Fully Occupied Office/Retail Center
$1,375,000

Fully Occupied Office/Retail Center

Seven-unit office/retail center with strong tenant mix and visibility.

18245 Us Highway 18, Apple Valley, CA 92307
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Apple Valley, CA Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in Apple Valley, CA with 16 listings featured on our commercial real estate exchange. The current inventory includes 2,117,843,640 square feet of properties with an estimated lease value of $19 SF/Yr.

Estimated lease rates for Office space in Apple Valley, CA begin at $1.20 SF/Yr, with an average of $4 SF/Yr and extend to $16 SF/Yr.
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