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    Portsmouth, OH Office Properties & Spaces for Sale

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    Versatile Commercial Property in Portsmouth
    $264,500
    2,208 SF

    Versatile Commercial Property in Portsmouth

    826 Gay St, Portsmouth, OH 45662

    High-visibility commercial property with versatile layout and living space.

    • Highly visible corner location across from Kroger, offering exceptional exposure.
    • Versatile layout suitable for various business uses (small business, office, meeting area).
    • On‑site parking for customers and employees.
    • Potential for a drive‑through business due to corner lot access from two streets.
    • Upstairs living space provides option to live where you work or rent for income.
    Updated: Mar 4
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    Downtown Portsmouth Commercial Building For Sale
    $525,000
    5,526 SF

    Downtown Portsmouth Commercial Building For Sale

    317 Chillicothe St, Portsmouth, OH 45662

    High-visibility commercial building with development potential in historic downtown Portsmouth.

    • High‑visibility location in the heart of historic downtown.
    • Versatile property with development potential on the wide‑open second floor.
    • Basement with 9‑foot ceilings and over 2,500 sq ft of usable space.
    • Recent upgrades include 16 tons of commercial A/C, new 3‑phase electrical, updated plumbing, and new windows.
    • Large display windows, high ceilings, and an open layout.
    Updated: Jan 6
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    Portsmouth Mixed-Use Commercial Property
    $499,000
    1,432 SF

    Portsmouth Mixed-Use Commercial Property

    Commercial property with office space and apartments in Portsmouth, OH.

    2629 Scioto Trl, Portsmouth, OH 45662
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    Commercial Building in Portsmouth, OH
    $199,000
    1,288 SF

    Commercial Building in Portsmouth, OH

    Commercial property suitable for medical or office use in Portsmouth.

    2002 Robinson Ave, Portsmouth, OH 45662
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    Furnished Office Space Available
    Contact for pricing
    0.11 Acres

    Furnished Office Space Available

    Furnished office space with utilities and amenities included.

    613 Chillicothe St, Portsmouth, OH 45662
    View details
    Based on your search, we've compiled 93 Potential Opportunities for your consideration. Besides 5 Active listings in Portsmouth, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 83 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Wheelersburg Commercial Building For Sale
    $799,000
    2,400 SF

    Wheelersburg Commercial Building For Sale

    High-visibility commercial building in Wheelersburg, suitable for various business types.

    8806 Ohio River Rd, Wheelersburg, OH 45694
    View details
    Wheelersburg Office Building For Sale
    $349,900
    5,084 SF

    Wheelersburg Office Building For Sale

    Two-story brick building near US 52 in Wheelersburg, OH.

    11672 Gallia Pike, Wheelersburg, OH 45694
    View details
    Medical Condo For Sale
    $199,900

    Medical Condo For Sale

    Medical condo with established office, suitable for medical practice.

    100 Saint Christopher Dr, Ashland, KY 41101
    View details
    Ashland Office Building - High Traffic Area
    $395,000
    2,675 SF

    Ashland Office Building - High Traffic Area

    Prime Office Space, 2675 SF, High Visibility

    701 Winchester Ave, Ashland, KY 41101
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Building in Boneyfiddle District
    $649,000
    6,515 SF

    Commercial Building in Boneyfiddle District

    Mixed-use commercial building with retail and garage spaces for sale.

    618 3Rd St, Portsmouth, OH 45662
    View details

    Explore Off-Market Properties in Portsmouth, OH

    Consider similar Off-Market properties in Portsmouth, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    711 Findlay St

    711 Findlay St

    OFFICE BUILDING • 576 SF
    Value Estimation by Request
    711 Findlay St, Portsmouth, OH 45662-4112
    View details
    721 7th St

    721 7th St

    MEDICAL CLINIC • 0.20 Acres
    Value Estimation by Request
    721 7th St, Portsmouth, OH 45662-4018
    View details
    1430 Chillicothe St

    1430 Chillicothe St

    MEDICAL CLINIC • 0.11 Acres
    Value Estimation by Request
    1430 Chillicothe St, Portsmouth, OH 45662-3444
    View details
    2114 Robinson Ave

    2114 Robinson Ave

    OFFICE BUILDING • 0.41 Acres
    Value Estimation by Request
    2114 Robinson Ave, Portsmouth, OH 45662-3743
    View details
    2808 Scioto Trl

    2808 Scioto Trl

    OFFICE BUILDING • 0.13 Acres
    Value Estimation by Request
    2808 Scioto Trl, Portsmouth, OH 45662-2244
    View details
    1616 Grant St

    1616 Grant St

    OFFICE BUILDING • 2,064 SF
    Value Estimation by Request
    1616 Grant St, Portsmouth, OH 45662-3663
    View details
    630 6th St

    630 6th St

    OFFICE BUILDING • 0.13 Acres
    Value Estimation by Request
    630 6th St, Portsmouth, OH 45662-3925
    View details
    745 7th St

    745 7th St

    OFFICE BUILDING • 0.05 Acres
    Value Estimation by Request
    745 7th St, Portsmouth, OH 45662-4018
    View details
    915 7th St

    915 7th St

    OFFICE BUILDING • 0.41 Acres
    Value Estimation by Request
    915 7th St, Portsmouth, OH 45662-4214
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    1500 Grant St

    1500 Grant St

    MEDICAL CLINIC • 0.12 Acres
    Value Estimation by Request
    1500 Grant St, Portsmouth, OH 45662-3606
    View details
    802 Chillicothe St

    802 Chillicothe St

    OFFICE BUILDING • 0.07 Acres
    Value Estimation by Request
    802 Chillicothe St, Portsmouth, OH 45662-4028
    View details
    601 Chillicothe St

    601 Chillicothe St

    OFFICE BUILDING (MULTI-STORY) • 0.04 Acres
    Value Estimation by Request
    601 Chillicothe St, Portsmouth, OH 45662-4023
    View details
    701 Chillicothe St

    701 Chillicothe St

    OFFICE BUILDING • 0.05 Acres
    Value Estimation by Request
    701 Chillicothe St, Portsmouth, OH 45662-4025
    View details
    301 Offnere St

    301 Offnere St

    OFFICE BUILDING • 0.13 Acres
    Value Estimation by Request
    301 Offnere St, Portsmouth, OH 45662-4655
    View details
    1915 Scioto Trl

    1915 Scioto Trl

    MEDICAL CLINIC • 0.30 Acres
    Value Estimation by Request
    1915 Scioto Trl, Portsmouth, OH 45662-2874
    View details
    1735 27th St

    1735 27th St

    MEDICAL CLINIC
    Value Estimation by Request
    1735 27th St, Portsmouth, OH 45662-2677
    View details
    6606 Gallia St

    6606 Gallia St

    OFFICE BUILDING • 512 SF
    Value Estimation by Request
    6606 Gallia St, Portsmouth, OH 45662-5646
    View details
    Scioto Trl

    Scioto Trl

    OFFICE BUILDING • 34.87 Acres
    Value Estimation by Request
    Scioto Trl, Portsmouth, OH 45662
    View details
    804 Chillicothe St

    804 Chillicothe St

    OFFICE BUILDING • 0.07 Acres
    Value Estimation by Request
    804 Chillicothe St, Portsmouth, OH 45662-4028
    View details

    Portsmouth, OH Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 88 office properties & spaces for sale in Portsmouth, OH, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 2,704,201 square feet of properties for sale, with an estimated market value of $19,033,500.

    Sale prices for office spaces in Portsmouth, OH start at $165,000, averaging $271,907, and reaching up to $615,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Portsmouth, OH

    Popular Searches in Portsmouth, OH

    Most Searched ZIP Codes in Portsmouth, OH

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