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    Portsmouth, OH Commercial Real Estate for Sale

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    Cleveland, OH Columbus, OH Cincinnati, OH
    18 results
    Downtown Portsmouth Commercial Building For Sale
    $525,000
    5,526 SF

    Downtown Portsmouth Commercial Building For Sale

    317 CHILLICOTHE, Portsmouth, OH 45662

    High-visibility commercial building with development potential in historic downtown Portsmouth.

    • High‑visibility location in the heart of historic downtown.
    • Versatile property with development potential on the wide‑open second floor.
    • Basement with 9‑foot ceilings and over 2,500 sq ft of usable space.
    • Recent upgrades include 16 tons of commercial A/C, new 3‑phase electrical, updated plumbing, and new windows.
    • Large display windows, high ceilings, and an open layout.
    Updated: Jan 6
    View details
    Historic Theater and Event Space
    $650,000
    8,243 SF

    Historic Theater and Event Space

    832 Gallia Street, Portsmouth, OH 45662

    Fully operational entertainment venue in downtown Portsmouth, Ohio.

    • Fully operational, revenue‑generating entertainment venue with strong brand recognition.
    • High capacity (up to 1150 patrons) suitable for diverse events.
    • Three bars and VIP seating enhance the event experience.
    • State‑of‑the‑art lighting and sound systems are already in place.
    • Flexible seating/standing configurations accommodate various event types.
    Updated: Jan 14
    View details
    Commercial Building in Boneyfiddle District
    $599,000
    6,515 SF

    Commercial Building in Boneyfiddle District

    Mixed-use commercial building with multiple spaces and garages.

    618 3rd St., Portsmouth, OH 45662
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    Portsmouth Commercial Building For Sale
    $349,000
    4,961 SF

    Portsmouth Commercial Building For Sale

    Commercial building in Portsmouth's Boneyfiddle District with multiple spaces.

    628 3rd St., Portsmouth, OH 45662
    View details
    Versatile Property in Clay Township
    $199,000
    8,832 SF

    Versatile Property in Clay Township

    Multi-use property with main building, duplex, and ample parking.

    1313 Rosemount Road, Portsmouth, OH 45662
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    Versatile Commercial Property in Portsmouth
    $264,500
    2,208 SF

    Versatile Commercial Property in Portsmouth

    High-visibility commercial property with versatile layout and living space.

    826 Gay St., Portsmouth, OH 45662
    View details
    Commercial Building in Excellent Condition
    $199,000
    1,288 SF

    Commercial Building in Excellent Condition

    Well-maintained commercial building with recent upgrades and versatile floor plan.

    2002 Robinson Avenue, Portsmouth, OH 45662
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    Commercial Building in Portsmouth, OH
    $169,000
    2,650 SF

    Commercial Building in Portsmouth, OH

    Commercial building with parking lot, endless possibilities for future usage.

    1016 Clay Street, Portsmouth, OH 45562
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    Portsmouth Mixed-Use Commercial Property
    $499,000
    1,432 SF

    Portsmouth Mixed-Use Commercial Property

    Commercial property with office space and apartments in Portsmouth, OH.

    2629 Scioto Trail, Portsmouth, OH 45662
    View details
    Commercial Building on Half Acre
    $64,500
    2,400 SF

    Commercial Building on Half Acre

    Commercial building with parking and customization potential in Portsmouth, OH.

    164 Bennett Street, Portsmouth, OH 45662
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    Portsmouth Commercial Building and Parking
    $990,000
    300 SF

    Portsmouth Commercial Building and Parking

    Commercial building with parking lots in Portsmouth, Ohio for sale.

    826 Chillicothe st, Portsmouth, OH 45662
    View details
    Commercial Land in Portsmouth, OH
    $79,900
    1,617 SF

    Commercial Land in Portsmouth, OH

    Affordable commercial land opportunity in Portsmouth, Ohio.

    1555 Gallia 1555, Portsmouth, OH 45662
    View details
    Portsmouth, OH Multi-Family Property
    $109,000
    1,800 SF

    Portsmouth, OH Multi-Family Property

    Multi-family property in Portsmouth, OH, totaling 1,800 square feet.

    1530 ST RT 139 unit: 1, Portsmouth, OH 45662
    View details
    Automatic Touchless Car Wash Facility
    $380,000
    1,440 SF

    Automatic Touchless Car Wash Facility

    24-hour automatic touchless car wash with vacuum stations.

    2715 Scioto Trail, Portsmouth, OH 45662
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    Furnished Office Space Available
    Contact for pricing
    0.11 Acres

    Furnished Office Space Available

    Furnished office space with utilities and amenities included.

    613 Chillicothe Street, Portsmouth, OH 45662
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    Land in High Traffic Area
    $39,900
    2.00 Acres

    Land in High Traffic Area

    Two-acre lot suitable for commercial or residential development.

    1130 A Rainbow Drive, Portsmouth, OH 45662
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    Automatic Touchless Car Wash For Sale
    $380,000
    1,440 SF

    Automatic Touchless Car Wash For Sale

    1,440 SF automatic touchless car wash with vacuum stations.

    2715 Scioto Trail, Portsmouth, OH 45662
    View details
    Commercial Land For Sale
    $99,999
    0.76 Acres

    Commercial Land For Sale

    Commercial land available in a great location.

    3624 US 23, Portsmouth, OH 45662
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 18 Active Listings in Portsmouth, OH, we suggest to view alternatives - similar 2393 Off-Market properties to explore as potential leads.

    Explore Off-Market Properties in Portsmouth, OH

    Consider similar Off-Market properties in Portsmouth, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    55 Riv Ave

    55 Riv Ave

    COMMERCIAL (GENERAL) • 0.09 Acres
    Value Estimation
    $1,300,000
    55 Riv Ave, Portsmouth, OH 45662-4712
    View details
    302 Campbell Ave

    302 Campbell Ave

    DRIVE-THRU RESTAURANT, FAST FOOD • 0.06 Acres
    Value Estimation by Request
    302 Campbell Ave, Portsmouth, OH 45662
    View details
    605 2nd Stb

    605 2nd Stb

    RETAIL STORES (PERSONAL SERVICES) • 0.06 Acres
    Value Estimation by Request
    605 2nd Stb, Portsmouth, OH 45662-3901
    View details
    1004 24th St

    1004 24th St

    OFFICE BUILDING • 1,924 SF
    Value Estimation by Request
    1004 24th St, Portsmouth, OH 45662-2822
    View details
    440 2nd St

    440 2nd St

    COMMERCIAL (GENERAL) • 0.06 Acres
    Value Estimation by Request
    440 2nd St, Portsmouth, OH 45662-3807
    View details
    1870 Coles Blvd

    1870 Coles Blvd

    MEDICAL CLINIC • 0.53 Acres
    Value Estimation by Request
    1870 Coles Blvd, Portsmouth, OH 45662-6900
    View details

    Portsmouth, OH Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2411 commercial real estate for sale in Portsmouth, OH, showcased through 18 active listings on our real estate platform. These investment opportunities span a total of 50,652 square feet of properties for sale, with an estimated market value of $5,456,900.

    Sale prices for business properties in Portsmouth, OH start at $64,500, averaging $363,793, and reaching up to $990,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Portsmouth, OH

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