Portsmouth, OH Commercial real estate for sale

Updated: Sep 25

Coworking Property with Apartment

613 Chillicothe Street, Portsmouth, OH 45662

$1,300,000

13,049 sqft 0.11 AC lot

13,049 square feet across two joined buildings
Accommodates 20 businesses, including 16 private offices; approximately 10% vacancy
Remodeled 1,020‑square‑foot apartment on the upper floor
Two conference rooms and three informal meeting areas
Three kitchens, four bathrooms, and an outdoor deck

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Updated: Aug 4

Office Building with Event Rooms

1701 Jackson St., Portsmouth, OH 45662

$499,000

5,544 sqft 0.26 AC lot

5,544‑square‑foot office building on 0.26 acres
Two large event rooms and 10 offices
Kitchen and restrooms on each floor
Within blocks of Shawnee State University
Commercial zoning at 1701 Jackson St.

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Mixed-Use Building with Apartment

4029 Gallia Street, Portsmouth, OH 45662

$375,000

6,702 sqft 0.29 AC lot

Church facilities and a second-floor residence create distinct community and residential areas.

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Scored against comparables nationwide. These are worth a look.

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Multi-Office Mixed-Use Building

1809 11th St., Portsmouth, OH 45662

$555,000

10,577 sqft

Commercial-zoned space combines office rooms, a conference room, and support areas with truck loading access beside the building.

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Flex Space with Office Buildout

1809 11th St., Portsmouth, OH 45662

$555,000

10,577 sqft

Multi-use layout includes offices, bathrooms, a conference room, freezer, and breakroom.

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Restaurant Property with Garage

1555, 63 Gallia Street & 9th street, Portsmouth, OH 45662

$350,000

5,310 sqft 0.29 AC lot

Commercial property combining a former restaurant, a substantial garage building, and two vacant frontage lots.

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Office Building with Private Offices

1613 Kinneys Lane, Portsmouth, OH 45662

$130,000

1,722 sqft

A dedicated staff area and waiting room complement the private-office layout.

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Coworking Space with Apartment

1-613 Chillicothe St, Portsmouth, OH 45662

$1,300,000

9,086 sqft

Furnished offices include utilities, internet, and phone service, alongside shared meeting rooms and lounge areas.

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Conventional Restaurant Building

1016 Clay Street, Portsmouth, OH 45562

$169,000

2,650 sqft

Commercially zoned restaurant property with dedicated parking across the street and existing building systems.

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Commercial Land

2002 Robinson Avenue, Portsmouth, OH 45662

$184,000

1,288 sqft 0.29 AC lot

Vacant commercial parcel with public water service and zoning identified as 499 Other Comme.

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Office Building with Event Space

1-1701 Jackson St, Portsmouth, OH 45662

$499,000

5,544 sqft

Multi-floor property includes offices, kitchens, restrooms, and flexible gathering areas.

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Street-Front Auto Shop

2715 Scioto Trail, Portsmouth, OH 45662

$250,000

1,440 sqft 0.38 AC lot

Block-and-concrete automotive building with radiant heating and a shingle roof.

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Commercial Specialty Property

Gallia 1555, Portsmouth, OH 45662

$79,900

1,617 sqft

Commercial property with central air, electric heat, and public water and sewer service.

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Office Building with Private Offices

1-1613 Kinneys Lane, Portsmouth, OH 45662

$130,000

1,722 sqft

A flexible office layout includes dedicated areas for visitors and staff, along with off-street parking.

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Land, Portsmouth, OH

Greenbriar Road, Portsmouth, OH 45648

$85,000

5.00 AC lot

Agricultural land / Farmland · 5.00 Acres

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Commercial Land Near Traffic Signal

3624 US 23, Portsmouth, OH 45662

$99,999

0.76 AC lot

Commercial-zoned land with electricity available and a traffic signal alongside the property.

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Multi-Use Flex Warehouse

1809-1809 11th St, Portsmouth, OH 45662

$555,000

10,577 sqft

Multi-use commercial space with office amenities and a freezer, plus truck loading area and parking.

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Restaurant Building with Parking Lot

1016 Clay Street, Portsmouth, OH 45562

$169,000

2,650 sqft

The existing restaurant layout is paired with a separate parking area across the street.

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Restaurant Property with Garage

2-1555, 63 Gallia St, Portsmouth, OH 45662

$350,000

6,927 sqft

The property combines a former restaurant building, a brick garage, and two vacant lots.

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Warehouse Property with Outdoor Space

0-2204 Gallia St, Portsmouth, OH 45662

$299,000

1.79 AC lot

Existing structural improvements occupy a substantial commercial tract with room for outdoor storage, fleet parking, or logistics operations.

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Retail Space with High-Traffic Visibility

3050 Walnut St, Portsmouth, OH 45662

Contact for pricing

10,718 sqft

Retail space offered with an absolute NNN lease structure and direct visibility to a high-traffic corridor.

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Standalone Office Building

1-626 7th St, Portsmouth, OH 45662

$82,500

1,136 sqft

A private kitchenette, full bathroom, and adjacent off-street parking support day-to-day office use.

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Furnished Coworking Space

613 Chillicothe Street, Portsmouth, OH 45662

Contact for pricing

Furnished offices include utilities, internet service, and a phone line.

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Automatic Touchless Car Wash For Sale

2715 Scioto Trail, Portsmouth, OH 45662

Contact for pricing

1,440 sqft

1,440 SF automatic touchless car wash with vacuum stations.

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Portsmouth, OH Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Portsmouth, OH, showcased through 25 active listings on our real estate platform. These investment opportunities span a total of 110,276 square feet of properties for sale, with an estimated market value of $8,016,399.

Sale prices for business properties in Portsmouth, OH start at $79,900, averaging $381,733, and reaching up to $1,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Portsmouth, OH CRE market trends — vacancy, lease rates and price per SF, updated monthly

Neighborhood	Average Price
Lucasville - 45648	$85K
Portsmouth - 45662	$442.9K

Neighborhood

Average Price

Lucasville - 45648

$85K

Portsmouth - 45662

$442.9K