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Jackson County, MI Office Spaces for Sale

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Single-Story Medical Office Building
Updated: Oct 24, 2025
Single-Story Medical Office Building

900 E Michigan Avenue, Jackson, MI 49201

$1,490,000
15,000 sqft 0.95 AC lot
5‑unit, single‑story brick medical office building (15,000 SF) on the East Michigan corridor
ADA‑compliant access with multiple entrances and ample on‑site parking
Central air cooling and forced‑air heating
Updated mechanical systems and composition roof
Cable available and broadband service
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900 E Michigan Avenue, Jackson, MI 49201

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Historic Live-Work Building
Updated: Jun 5
Historic Live-Work Building

505 Wildwood Avenue, Jackson, MI 49201

$550,000
6,357 sqft 0.30 AC lot
Historic downtown Jackson property built in 1900 with brick construction and a slate roof
8 bedrooms with 2 full baths and 3 half baths across four levels of usable space
Described as having flexible zoning for a range of uses, including retail, professional offices, mixed‑use, event space, B&B/Airbnb, room rentals, live/work, and multifamily conversion
2019 updates included substantial plumbing and electrical updates and extensive drywall repairs
Upper levels added mini‑split heating and cooling; 2021 added a new HVAC system for the main level
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Former Bank Branch Office Building
Former Bank Branch Office Building

301 N Jackson Street, Jackson, MI 49201

$1,100,000
7,280 sqft 1.13 AC lot

Class A office and medical space with on-site parking and building signage, suited for professional or service-oriented users.

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Two-Story Flex Industrial Building
Two-Story Flex Industrial Building

1716 Wildwood Avenue, Jackson, MI 49202

$289,900
3,776 sqft 0.22 AC lot

Two-story commercial building in Jackson Township offers office space with I-2 general industrial zoning versatility.

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Single-Story Medical Office Building
Single-Story Medical Office Building

900 E Michigan Avenue, Jackson, MI 49201

$1,490,000
15,000 sqft

Purpose-built, well-maintained single-story medical office with five units, multiple entrances, ADA access, and ample parking.

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Updated Office Building with Parking
Updated Office Building with Parking

1110 W Michigan Avenue, Jackson, MI 49202

$170,000
2,652 sqft 0.14 AC lot

Well-maintained office building with private workspaces, two restrooms, and off-street parking for staff and clients.

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Downtown Mixed-Use Flex Property
Downtown Mixed-Use Flex Property

711 E Michigan Avenue, Jackson, MI 49201

$499,900
16,200 sqft 0.43 AC lot

Two buildings totaling about 16,200 SF plus an adjacent vacant lot, with loading docks and mixed office, retail, and warehouse space.

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Versatile Shop and Office Space
Versatile Shop and Office Space

204 Homewild Avenue, Jackson, MI 49201

$165,000
4,284 sqft 0.31 AC lot

Meticulously maintained industrial property in Jackson's Northside with versatile space.

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Clarklake Commercial Facility For Sale
Clarklake Commercial Facility For Sale

9486 S Meridian Rd, Clarklake, MI 49234

$595,000
4,656 sqft

High-visibility commercial facility with office and shop space.

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General Commercial Block Building
General Commercial Block Building

608 E Pearl Street, Jackson, MI 49201

$124,900
1,176 sqft 0.37 AC lot

C-4 commercial building with open work area, private office, and bathroom, plus natural gas forced-air and wall furnace.

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Commercial Property on 3 Acres
Commercial Property on 3 Acres

2840 Shirley Drive, Jackson, MI 49201

$265,000
5,350 sqft 3.00 AC lot

Commercial property with frontage on US127 and easy highway access.

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Medical Office Suite with Basement
Medical Office Suite with Basement

2575 Spring Arbor Road 100, Jackson, MI 49203

$127,800
1,278 sqft

Well-maintained suite with three exam rooms, private office, reception, waiting area, plus basement storage and systems space.

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Medical Office Suite in Professional Park
Medical Office Suite in Professional Park

2575 Spring Arbor Road, Jackson, MI 49203

$127,800
1,278 sqft 0.03 AC lot

Well-maintained medical office suite with exam rooms, private office, reception, waiting room, and basement storage space.

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Turnkey Office Building with Storage Shed
Turnkey Office Building with Storage Shed

227 E State Street, Hanover, MI 49241

$230,000
2,079 sqft 1.67 AC lot

Move-in ready office building with two-zone heating, two bathrooms, kitchen area, and a 10' x 16' storage shed.

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Class A Former Bank Branch
Class A Former Bank Branch

301 N Jackson Street, Jackson, MI 49201

$1,100,000
7,280 sqft

Class A office building constructed in 2021, offering a remaining suite for lease alongside an executed 10-year bank lease.

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Remodeled Office Condo Unit
Remodeled Office Condo Unit

3465 Ann Arbor Road, Jackson, MI 49202

$299,900
2,254 sqft 0.12 AC lot

Remodeled office condo with two restrooms, kitchen, acoustical ceiling panels, and front and rear entrances.

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Office and Lab Facility on Acreage
Office and Lab Facility on Acreage

3000 Blake Road, Jackson, MI 49201

$4,100,000
41,776 sqft 25.50 AC lot

Versatile corporate headquarters with dock, backup generator, and strong flexibility for office, medical, or lab users.

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Turnkey Commercial Opportunity in Hanover
Turnkey Commercial Opportunity in Hanover

227 E State St, Hanover, MI 49241

$259,000
2,000 sqft 1.50 AC lot

Well-maintained commercial building with versatile space on a generous lot.

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Industrial Facility with Office & Shop
Industrial Facility with Office & Shop

9486 S Meridian Road, Clarklake, MI 49234

$595,000
4,656 sqft 2.42 AC lot

High-visibility industrial zoned facility with heated shop, office buildout, overhead doors, and heavy-duty floor.

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Large Industrial Building Near M-50
Large Industrial Building Near M-50

1002 E South St, Jackson, MI 49203

$169,900
18,000 sqft 3.50 AC lot

18,000 SF building on 3.5 acres near M-50.

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Versatile Retail/Office Storefront
Versatile Retail/Office Storefront

108 Grand Street, Michigan Center, MI 49254

$100,000
420 sqft 0.10 AC lot

Former barbershop with updated roof, systems, and interior improvements, plus an office with separate entrances.

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Downtown Office Building with Elevator
Downtown Office Building with Elevator

145 S Jackson Street, Jackson, MI 49201

$425,000
18,000 sqft

Three-floor office building with elevator access, furnished lobby, multiple restrooms, and flexible suite configuration.

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Downtown Jackson Office/Multifamily Building
Downtown Jackson Office/Multifamily Building

400 S Jackson St, Jackson, MI 49201

$325,000
2,064 sqft

2,064 SF office/multifamily building in downtown Jackson.

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All-Brick Medical Office Building
All-Brick Medical Office Building

2600 Spring Arbor Road, Jackson, MI 49203

$425,000
5,670 sqft 1.17 AC lot

Turnkey all-brick building with multiple exam rooms, private offices, and extensive staff amenities for healthcare and professional services.

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Jackson County, MI Office Spaces Market Trends and Statistics

Explore 83 office spaces for sale in Jackson County, MI, showcased through 83 active listings on our real estate platform. These investment opportunities span a total of 512,321 square feet of properties for sale, with an estimated market value of $38,352,900.

Sale prices for office spaces in Jackson County, MI start at $64,800, averaging $608,776, and reaching up to $5,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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