Frederick County, MD Office Spaces for sale

Frederick Office/Medical Building For Sale

$3,250,000

1.03 Acres

Frederick Office/Medical Building For Sale

195 THOMAS JOHNSON Drive, Frederick, MD 21702

10,600 SF office/medical building with onsite parking and natural light.

Freestanding 10,600 SF building offers independence and prominent visibility.
Flexible layout suits medical, dental, professional office, or daycare use.
Approximately 5,000 SF recently updated for medical/professional office use.
Onsite parking available.
Abundant natural light throughout the building.

Updated: Jan 14

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$789,900

2,848 SF

Downtown Frederick Office/Medical Space

241 E 4TH Street, Frederick, MD 21701

2,848 SF office/medical space in historic downtown Frederick.

2,848 SF Office/Medical Space in Historic Downtown Frederick
Five Offices, Conference Room, Three Large Open Cubicle Areas, Large Full Kitchen
Located on East Street with on‑street and parking lot options
Three AC Units within the Suite
Multiple Restrooms and Breakroom in Common Area

Updated: May 16, 2025

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$419,999

1,520 SF

Frederick Office Suite For Sale

Street-level office suite with tax benefits and modern design.

6550 MERCANTILE Drive E, Frederick, MD 21703

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Freestanding Office/Medical Building For Sale

$3,250,000

10,600 SF

Freestanding Office/Medical Building For Sale

10,600 SF office/medical building with on-site parking and natural light.

195 THOMAS JOHNSON Dr, Frederick, MD 21702

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$585,000

1,851 SF

Luxury Office Condo in Frederick

Class A office condo in vibrant Downtown Frederick location.

50 Carroll Creek Way, Frederick, MD 21701

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Versatile Commercial Building Near Interstates

$1,800,000

6,000 SF

Versatile Commercial Building Near Interstates

6,000 sq ft commercial building suitable for industrial or flex uses.

4603 Wedgewood Blvd, Frederick, MD 21703

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$2,100,000

Prime Commercial Property For Sale

Commercial property with warehouse space and easy highway access.

106 N CHURCH STREET, Middletown, MD 21769

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$745,000

Frederick Commercial Property with Parking

Commercial property with two buildings and ample parking spaces.

7004 ROCK CREEK Dr, Frederick, MD 21702

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$3,500,000

15,866 SF

Fully Occupied Investment Opportunity

15,866 SF building with 100% occupancy in Twin Arch.

2904 BACK ACRE Cir, Mount Airy, MD 21771

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$299,900

1,214 SF

Mount Airy Commercial Space Available

Commercial space for sale in Mount Airy, Maryland.

401 CENTER STREET 1, Mount Airy, MD 21771

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$900,000

3,087 SF

Medical Office Condominium in Frederick

Turnkey 3,087 SF medical office condo in Frederick, MD.

6550 Mercantile Dr E, Frederick, MD 21703

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$719,000

0.20 Acres

Historic Building with Updated Interior

Updated historic building suitable for a small business owner.

3504 Urbana Pike, Urbana, MD 21704

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$465,000

1,653 SF

Remodeled Office Space with Furnishings

Fully furnished, remodeled office space available for rent.

127-129 5 W Patrick St, Frederick, MD

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$3,000,000

10,000 SF

Historic Building on Carroll Creek

Three-story building in historic downtown Frederick with commercial/residential zoning.

47 E ALL SAINTS STREET, Frederick, MD 21701

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$439,000

Frederick Mixed-Use Property For Sale

Mixed-use property with commercial potential in a vibrant Frederick location.

431 Patrick St, Frederick, MD 21701

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$4,995,000

20,000 SF

Versatile Flex/Warehouse Facility

20,000 SF flex/warehouse facility in Frederick, Maryland.

4102 Harvard Pl, Frederick, MD

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$1,650,000

0.99 Acres

Mixed-Use Property on Route 27

Two-parcel commercial property suitable for mixed-use development.

806 PARK AVENUE, Mount Airy, MD 21771

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Prime Development Opportunity in Ijamsville

$6,500,000

3,592 SF

Prime Development Opportunity in Ijamsville

49.84 acre parcel for future office/research/industrial development.

9920 Doctor Perry Rd, Ijamsville, MD 21754

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$1,350,000

0.08 Acres

Historic Mixed-Use Property For Sale

Historic property with commercial and residential potential in Frederick, MD.

110 N Court St, Frederick, MD 21701

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$995,000

3,000 SF

Renovated Building Near Green Hill

Versatile renovated building with ample parking and accessibility features.

5529 ADAMSTOWN ROAD, Adamstown, MD 21710

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$1,300,000

Historic Mixed-Use Complex For Sale

Mixed-use complex in Hub and Opportunity Zone with unlimited potential.

37-39 E South St #4-5, Frederick, MD 21701

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Elevatored Office Building on Thomas Johnson

$1,100,000

654 SF

Elevatored Office Building on Thomas Johnson

Three-level condo offices ranging from 654 SF to 7,751 SF.

57 Thomas Johnson Dr, Frederick, MD

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$425,000

0.06 Acres

Mixed-Use Investment Property

Mixed-use property in downtown Walkersville with commercial and residential potential.

21 Pennsylvania Ave W, Walkersville, MD 21793

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$2,500,000

Commercial Suites in Urbana

Professional business and retail suites with high visibility and accessibility.

3535 URBANA Pike, Frederick, MD 21704

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Frederick County, MD Office Spaces Investment Opportunities Market Analysis

Explore 72 office spaces for sale in Frederick County, MD, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 122,236 square feet of properties for sale, with an estimated market value of $37,649,799.

Sale prices for office spaces in Frederick County, MD start at $299,900, averaging $2,353,112, and reaching up to $6,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.