Add Listing
    Maryland
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Frederick County, MD Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Baltimore, MD Columbia, MD Rockville, MD
    201 results
    Westview Village
    View details
    Renovated Office Space with Utilities
    $1,800/Mo

    Renovated Office Space with Utilities

    13146 OLD NATIONAL Pike, Mount Airy, MD 21771

    Move-in ready office space with flexible lease terms available.

    • All utilities included in lease.
    • Move‑in ready, freshly renovated office space.
    • Highly accessible location near Mt. Airy, I‑70, and Frederick.
    • Flexible lease terms available.
    • Includes three private offices, large open work area, full kitchen, and private full bathroom.
    Updated: Feb 25
    View details
    Charming Frederick Office Space Available
    $800/Mo

    Charming Frederick Office Space Available

    3390 URBANA Pike, Frederick, MD 21704

    Elegant office space in a character-rich building with ample parking.

    • Prime location with strategic accessibility and prestigious community presence.
    • Dedicated parking lot for convenient client and employee parking.
    • High ceilings and abundant natural light create an uplifting and inspiring workspace.
    • Opportunity to create a bespoke interior space tailored to specific business needs.
    • Charming, character‑rich building with a professional and welcoming atmosphere.
    Updated: Dec 11, 2025
    View details
    Prime Retail Space in Brunswick
    $2,000/Mo
    950 SF

    Prime Retail Space in Brunswick

    950 SF retail space in the heart of Brunswick.

    2 E POTOMAC Street, Brunswick, MD 21716
    View details
    Charming Frederick Commercial Lease Opportunity
    $800/Mo

    Charming Frederick Commercial Lease Opportunity

    Charming commercial lease with historic elegance and modern functionality.

    3390 URBANA Pike, Frederick, MD 21704
    View details
    Charming Frederick Commercial Lease Opportunity
    $800/Mo

    Charming Frederick Commercial Lease Opportunity

    Elegant commercial space with historic charm and modern functionality.

    3390 URBANA Pike, Frederick, MD 21704
    View details
    Renovated Commercial Property in Urbana
    $3,750/Mo

    Renovated Commercial Property in Urbana

    Renovated commercial property ideal for retail or office use.

    8832 URBANA CHURCH Road, Urbana, MD 21704
    View details
    Professional Office Suite in Mt. Airy
    $2,900/Mo

    Professional Office Suite in Mt. Airy

    Well-designed office suite with excellent functionality and visibility.

    602 CENTER Street, Mount Airy, MD 21771
    View details
    Charming Frederick Commercial Lease Opportunity
    $800/Mo

    Charming Frederick Commercial Lease Opportunity

    Elegant commercial space with negotiable lease terms in Frederick, MD.

    3390 URBANA Pike, Frederick, MD 21704
    View details
    Retail Space in Shell Condition
    $20 SF/Yr

    Retail Space in Shell Condition

    2,279 SF retail or restaurant space for lease.

    358 W PATRICK Street, Frederick, MD 21701
    View details
    Stand-Alone Building in Frederick, MD
    $14 SF/Yr

    Stand-Alone Building in Frederick, MD

    7,844 SF stand-alone building with second floor available for lease.

    6008 FAIR OAKS Drive, Frederick, MD 21703
    View details
    Frederick MD Office/Medical Building
    $23 SF/Yr

    Frederick MD Office/Medical Building

    Freestanding office/medical building with parking and natural light for lease.

    195 THOMAS JOHNSON Drive, Frederick, MD 21702
    View details
    Frederick Commercial Space with Drive-Through
    $18 SF/Yr

    Frederick Commercial Space with Drive-Through

    Versatile commercial space in Frederick, ideal for various businesses.

    198 THOMAS JOHNSON Drive, Frederick, MD 21701
    View details
    Medical Space For Lease
    $650/Mo

    Medical Space For Lease

    Medical space available for lease in Frederick, Maryland.

    286 MONTEVUE Lane, Frederick, MD 21702
    View details
    Frederick Commercial Space with Drive-Through
    $18 SF/Yr

    Frederick Commercial Space with Drive-Through

    Versatile commercial space in Frederick, ideal for various businesses.

    198 THOMAS JOHNSON Drive, Frederick, MD 21701
    View details
    Historic Downtown Frederick Office Space
    $20 SF/Yr

    Historic Downtown Frederick Office Space

    Charming office building in historic Downtown Frederick.

    22 SECOND Street E, Frederick, MD 21701
    View details
    Frederick Commercial Space For Lease
    $18 SF/Yr

    Frederick Commercial Space For Lease

    Highly visible commercial space with ADA access and ample parking.

    198 THOMAS JOHNSON Drive, Frederick, MD 21701
    View details
    Frederick Office Space For Lease
    $10 SF/Yr

    Frederick Office Space For Lease

    Office space with workstations, labs, kitchen, and parking.

    241 E 4TH Street, Frederick, MD 21701
    View details
    Office Space in Frederick, MD
    $400/Mo

    Office Space in Frederick, MD

    Commercial office space available for lease in Frederick, Maryland.

    322 W PATRICK Street, Frederick, MD 21701
    View details
    Office Space in Frederick, MD
    $2,120/Mo

    Office Space in Frederick, MD

    Office space available for lease in Frederick, Maryland.

    6550 MERCANTILE Drive E, Frederick, MD 21703
    View details
    Frederick Warehouse Retail Sublease Available
    $8 SF/Yr

    Frederick Warehouse Retail Sublease Available

    4,800 SF warehouse retail sublease in Frederick, Maryland.

    622 N MARKET Street, Frederick, MD 21701
    View details
    Second Floor Office Space Available
    $875/Mo
    3,000 SF

    Second Floor Office Space Available

    Second floor office space in Frederick, MD for rent.

    174 THOMAS JOHNSON Dr 201L, Frederick, MD 21702
    View details
    Downtown Frederick Retail or Restaurant
    $20 SF/Yr
    2,279 SF

    Downtown Frederick Retail or Restaurant

    2,279 SF first-floor space in historic downtown Frederick.

    358 W PATRICK St, Frederick, MD 21701
    View details
    Industrial Condominium Unit For Rent
    $14 SF/Yr
    5,652 SF

    Industrial Condominium Unit For Rent

    5,652 SF condominium unit for rent near Frederick Airport.

    331 AVIATION Way UNIT 6, Frederick, MD 21701
    View details

    Frederick County, MD Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Frederick County, MD with 201 listings featured on our commercial real estate exchange. The current inventory includes 388,217 square feet of properties with an estimated lease value of $1,015 /Mo.

    Estimated lease rates for Commercial real estate in Frederick County, MD begin at $3 SF/Yr, with an average of $20 SF/Yr and extend to $140 SF/Yr.
    List
    Map

    Commercial real estate by market

    Browse Commercial real estate for Lease Near Frederick, MD

    Popular Searches in Frederick

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!