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    Desoto, TX Office Spaces for Lease

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    TX, Cedar Hill - Uptown Village
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    DeSoto Retail or Office Space
    Updated: Nov 24, 2025
    DeSoto Retail or Office Space

    2021 N Hampton Rd, Desoto, TX

    $16 SF/Yr
    1,000 sqft $1,333/Mo
    Office or retail space available
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    DeSoto Office Space For Rent
    Updated: Nov 24, 2025
    DeSoto Office Space For Rent

    1229 E Pleasant Run Rd, Desoto, TX

    $21.50 SF/Yr
    373 sqft $668.29/Mo
    Single office space
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    DeSoto Retail and Office Space
    DeSoto Retail and Office Space

    320-360 E Belt Line Rd, Desoto, TX

    $925/Mo
    430 sqft $25.81 SF/Yr

    26,000 SF marketplace with retail, restaurant, and office spaces.

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    Hampton Road Retail/Office Space
    Hampton Road Retail/Office Space

    712 N Hampton Rd, Desoto, TX

    $1,716/Mo
    1,950 sqft $10.56 SF/Yr

    One-story brick retail/office center on Hampton Road.

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    Office Space with Private Offices
    Office Space with Private Offices

    1636 N Hampton Rd, Desoto, TX

    $14.50 SF/Yr
    1,669 sqft $2,016/Mo

    Office space featuring reception area, private offices, and storage.

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    Desoto Office Space For Rent
    Desoto Office Space For Rent

    911 N HAMPTON ROAD, Desoto, TX 75115

    Contact for pricing
    18,643 sqft

    Office suites available for lease in Desoto, Texas.

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    Office Space with Corner Location
    Office Space with Corner Location

    1801 N Hampton Rd, Desoto, TX 75115

    $22 SF/Yr
    1,060 sqft $1,943/Mo

    Office unit featuring reception area, window offices, and corner location.

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    DeSoto Office Space Available
    DeSoto Office Space Available

    1510 N Hampton Rd, Desoto, TX

    Contact for pricing
    2,359 sqft

    Office space available for rent in DeSoto, Texas.

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    DeSoto Office Building For Rent
    DeSoto Office Building For Rent

    1801 N Hampton Rd, Desoto, TX 75115

    $23.27 SF/Yr
    68,000 sqft $131,863/Mo

    68,000+ sq ft office building with on-site amenities.

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    Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 10 Active listings in Desoto, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 13 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Two-Office Suite for Rent
    Two-Office Suite for Rent

    300 E Wheatland Road, Duncanville, TX 75116

    $1,700/Mo

    Two built-in office rooms include shelving and cabinetry, with the front office larger than the back office.

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    Endcap Medical Office Suite
    Endcap Medical Office Suite

    3571 W Wheatland Rd, Dallas, TX 75237

    Contact for pricing
    4,000 sqft

    Endcap medical office with Wheatland Road frontage and immediate availability, adjacent to Methodist Charlton Medical Center.

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    Duncanville Office Space Available
    Duncanville Office Space Available

    1314 S Main St, Duncanville, TX

    Contact for pricing
    1,013 sqft

    Office space for rent in Duncanville, Texas, 1013 square feet.

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    Office Space Available For Lease
    Office Space Available For Lease

    7999 W Virginia Dr, Dallas, TX 75237

    $21 SF/Yr

    Office space for lease at 7999 W Virginia Dr, Dallas.

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    Similar Spaces for Sale in Desoto, TX

    Consider Similar Space for Sale. We found 13 Spaces matching your search parameters.

    Medical Office and Service Building
    Medical Office and Service Building

    701 N Hampton Road, Desoto, TX 75115

    $525,000
    0.34 AC lot

    Well-located building suited for medical, professional services, or retail conversion with strong visibility and parking.

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    Office Building with Full Kitchen
    Office Building with Full Kitchen

    718 N Hampton Road, Desoto, TX 75115

    $1,500,000
    2.00 AC lot

    A 1955 office building with multiple rooms and a full kitchen on a generous lot for flexible use.

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    Flex Warehouse with Office
    Flex Warehouse with Office

    400 E Centre Park Boulevard, Desoto, TX 75115

    $3,295,000
    1.53 AC lot

    Flex warehouse and office space with NNN leases in place and the building currently 100% occupied.

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    Multi-Suite Office Building
    Multi-Suite Office Building

    1701 N Hampton Road, Desoto, TX 75115

    $1,500,000
    1.03 AC lot

    13,565 SF office building features multiple suites, break rooms, conference rooms, and 11 bathrooms.

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    Flex Office Warehouse with Grade-Level Doors
    Flex Office Warehouse with Grade-Level Doors

    1101 S Hampton Road, Desoto, TX 75115

    $1,980,000
    0.95 AC lot

    Light industrial and distribution users benefit from a flexible office-warehouse layout, heavy power, and ample off-street parking.

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    Commercial Building on Large Lot
    Commercial Building on Large Lot

    718 N Hampton Road, Desoto, TX 75115

    $1,500,000
    1,960 sqft 2.00 AC lot

    1,960 SF commercial building on 2 acre lot.

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    Live-Work Property with Attached Studio
    Live-Work Property with Attached Studio

    121 Little John dr, Desoto, TX 75115

    $435,000
    3.34 AC lot

    Residential home with three bedrooms and two baths plus an attached studio on over three acres, zoned General retail.

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    Desoto Office Building For Sale
    Desoto Office Building For Sale

    1701 N Hampton Road, Desoto, TX 75115

    $1,500,000
    13,565 sqft

    13,565 SF office building in Desoto, Texas.

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    DeSoto Office Space Available
    DeSoto Office Space Available

    315 E Pleasant Run Rd, Desoto, TX

    $385,000
    3,000 sqft 1.13 AC lot

    3000 square foot office space in DeSoto, Texas.

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    Updated Medical Office Condo
    Updated Medical Office Condo

    2727 Bolton Boone Dr, Desoto, TX

    $631,680
    2,688 sqft 1.92 AC lot

    2,688 SF medical office near Charlton Methodist Hospital.

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    DeSoto Flex Space Investment Opportunity
    DeSoto Flex Space Investment Opportunity

    400 E Centre Park Blvd Ste 101, Desoto, TX 75115

    $3,295,000
    1.53 AC lot

    100% occupied flex space near I-35, ideal for investors.

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    DeSoto Flex/Industrial/Office Property For Sale
    DeSoto Flex/Industrial/Office Property For Sale

    1301 E Parkerville Rd, Desoto, TX 75115

    $2,300,000
    20,000 sqft

    20,000 SF flex, industrial, and office property in DeSoto, TX.

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    DeSoto Commercial Revitalization Opportunity
    DeSoto Commercial Revitalization Opportunity

    123 Executive Way, Desoto, TX

    Contact for pricing
    10,800 sqft 0.73 AC lot

    Income-producing property in area earmarked for commercial revitalization.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Pad Site Near Baylor
    Prime Pad Site Near Baylor

    722 S 7th Street, Waco, TX 76706

    $105,000 SF/Yr
    30,797 sqft $269,473,750/Mo

    30,798 SF lot near Baylor and Magnolia Silos.

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    Build-to-Suit Retail/Office Buildings
    Build-to-Suit Retail/Office Buildings

    5647 KPE Way, Tyler, TX 75703

    $3,480/Mo

    Retail or office build-to-suit with C-1 zoning and 99 parking spaces.

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    Build-to-Suit Office Land Parcel
    Build-to-Suit Office Land Parcel

    5637 Paluxy Dr, Tyler, TX 75703

    $20,000/Mo
    20,000 sqft $12 SF/Yr

    Land offering build-to-suit development flexibility for an office complex in South Tyler near major roadways.

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    Corner Retail and Office Building
    Corner Retail and Office Building

    325 E Highway 29, Bertram, TX 78605

    $2,000/Mo
    2,000 sqft $12 SF/Yr

    Corner commercial building with three separate suites, offering flexible leasing for retail, office, or service uses.

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    Desoto, TX Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Desoto, TX with 10 listings featured on our commercial real estate exchange. The current inventory includes 74,482 square feet of properties with an estimated lease value of $133.64 SF/Yr.

    Estimated lease rates for Office Spaces in Desoto, TX begin at $10.56 SF/Yr, with an average of $19.09 SF/Yr and extend to $25.81 SF/Yr.
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