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    Desoto, TX Commercial Real Estate for Lease

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    23 properties
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    Prime Medical Office Development Land
    Updated: Apr 29
    Prime Medical Office Development Land

    1700 N Westmoreland Road, Desoto, TX 75115

    $3,989/Mo
    0.524‑acre commercial land parcel along N. Westmoreland Rd corridor in DeSoto, TX
    Utilities available: public water and public sewer
    Located within a growing commercial medical office development area
    Development flexibility: build to suit, ground lease, or owner‑user construction
    Year built: 2026 (under construction)
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    Retail Center in High-Traffic Area
    Updated: Apr 8
    Retail Center in High-Traffic Area

    1240 W. BELT LINE RD., Desoto, TX 75115

    Contact for pricing
    9,967 sqft
    Fully leased Class A retail center.
    Located at a high‑profile intersection of W. Belt Line Road and S. Cockrell Hill Road.
    Strong mix of national and local restaurants, services, and retail options.
    Located in a dense residential area along a retail corridor with major retailers such as Albertsons, CVS, and Walmart.
    Trade area with approximately 72,000 residents and an average household income of more than $88,000 (within a three‑mile radius).
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    DeSoto Retail or Office Space
    DeSoto Retail or Office Space

    2021 N Hampton Rd, Desoto, TX

    $16 SF/Yr
    1,000 sqft

    1000 square feet of retail or office space available.

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    DeSoto Office Space For Rent
    DeSoto Office Space For Rent

    1229 E Pleasant Run Rd, Desoto, TX

    $21.50 SF/Yr
    373 sqft

    Office space available for lease in DeSoto, Texas.

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    DeSoto Retail and Office Space
    DeSoto Retail and Office Space

    320-360 E Belt Line Rd, Desoto, TX

    $925/Mo
    430 sqft

    26,000 SF marketplace with retail, restaurant, and office spaces.

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    Retail and Medical Space Available
    Retail and Medical Space Available

    1314 W WINTERGREEN RD, Desoto, TX 75115

    Contact for pricing
    19,018 sqft

    Newly constructed retail space ideal for various business concepts.

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    Hampton Road Retail/Office Space
    Hampton Road Retail/Office Space

    712 N Hampton Rd, Desoto, TX

    $1,716/Mo
    1,950 sqft

    One-story brick retail/office center on Hampton Road.

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    DeSoto Flex Space Available
    DeSoto Flex Space Available

    1516 Osprey Dr, Desoto, TX

    $12 SF/Yr
    1,750 sqft

    Flex space featuring reception area, offices, storage, and break area.

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    Office Space with Private Offices
    Office Space with Private Offices

    1636 N Hampton Rd, Desoto, TX

    $14.50 SF/Yr
    1,669 sqft

    Office space featuring reception area, private offices, and storage.

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    Desoto Office Space For Rent
    Desoto Office Space For Rent

    911 N HAMPTON ROAD, Desoto, TX 75115

    Contact for pricing
    18,643 sqft

    Office suites available for lease in Desoto, Texas.

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    Office Space with Corner Location
    Office Space with Corner Location

    1801 N Hampton Rd, Desoto, TX 75115

    $22 SF/Yr
    1,060 sqft

    Office unit featuring reception area, window offices, and corner location.

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    DeSoto Flex Space Available
    DeSoto Flex Space Available

    205 Executive Way, Desoto, TX 75115

    Contact for pricing
    8,750 sqft

    Flex space available in DeSoto, Texas.

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    Freestanding Restaurant with Banquet Room
    Freestanding Restaurant with Banquet Room

    1109 E Pleasant Run Rd, Desoto, TX 75115

    Contact for pricing

    Turnkey freestanding restaurant with fully equipped kitchen, private events space, and ample parking on a high-traffic corridor.

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    DeSoto Office Space Available
    DeSoto Office Space Available

    1510 N Hampton Rd, Desoto, TX

    Contact for pricing
    2,359 sqft

    Office space available for rent in DeSoto, Texas.

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    Industrial Property for Lease
    Industrial Property for Lease

    205 Executive Way |, Desoto, TX 75115

    Contact for pricing
    8 sqft

    Industrial property available for lease in DeSoto, Texas.

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    DeSoto Warehouse Space Available
    DeSoto Warehouse Space Available

    316 Ezell Dr, Desoto, TX

    Contact for pricing
    5,950 sqft

    5,950 SF warehouse space for rent in DeSoto, TX.

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    DeSoto Industrial Space Available
    DeSoto Industrial Space Available

    2050 Kestrel Ave, Desoto, TX

    Contact for pricing
    35,000 sqft

    Industrial space for lease with excellent highway access.

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    Retail Space in DeSoto, TX
    Retail Space in DeSoto, TX

    1100 E Pleasant Run Rd, Desoto, TX

    $14 SF/Yr
    1,293 sqft

    Retail spaces available in a busy shopping center.

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    Retail Space in DeSoto, Texas
    Retail Space in DeSoto, Texas

    921 W Belt Line Rd, Desoto, TX

    Contact for pricing
    6,700 sqft

    Retail spaces available in DeSoto, Texas, with high visibility.

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    Former Big Lots Retail Space
    Former Big Lots Retail Space

    719 N Hampton Rd, Desoto, TX 75115

    Contact for pricing

    Retail, office, medical, and restaurant space in Locke Supply center.

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    Retail Space in DeSoto, Texas
    Retail Space in DeSoto, Texas

    901 N Polk St, Desoto, TX 75115

    $10 SF/Yr

    Retail property located near Interstate 35 in DeSoto, Texas.

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    Industrial Land For Lease
    Industrial Land For Lease

    917 E Centre Park Blvd, Desoto, TX

    Contact for pricing

    Industrial zoned land with utilities available and highway access.

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    DeSoto Office Building For Rent
    DeSoto Office Building For Rent

    1801 N Hampton Rd, Desoto, TX 75115

    $23.27 SF/Yr
    68,000 sqft

    68,000+ sq ft office building with on-site amenities.

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    Based on your search, we've compiled 67 Potential Opportunities for your consideration. Besides 23 Active listings in Desoto, TX, we suggest exploring alternatives. Similar 44 Properties for Sales.

    Similar Spaces for Sale in Desoto, TX

    Consider Similar Space for Sale. We found 44 Spaces matching your search parameters.

    Medical Office and Service Building
    Medical Office and Service Building

    701 N Hampton Road, Desoto, TX 75115

    $525,000
    0.34 AC lot

    Well-located building suited for medical, professional services, or retail conversion with strong visibility and parking.

    View details

    Desoto, TX Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Desoto, TX with 23 listings featured on our commercial real estate exchange. The current inventory includes 77,525 square feet of properties with an estimated lease value of $159.64 SF/Yr.

    Estimated lease rates for Commercial real estate in Desoto, TX begin at $10.56 SF/Yr, with an average of $17.74 SF/Yr and extend to $25.81 SF/Yr.
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