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    Greenville, NC Office Spaces for Lease

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    Winterville, NC Simpson, NC Jefferson, NC
    25 listings
    Medical Office Space in Medical District
    $1,500/Mo
    1,250 SF
    Medical Office Space in Medical District

    835 Johns Hopkins Drive, Greenville, NC 27834

    Medical office space available for lease within Greenville’s medical district, suited for healthcare-related office use.
    • Office space available for lease in Greenville's Medical District.
    • Prime location in the Medical District of Greenville, NC.
    • Built in 2000.
    • Features electric heating.
    • Location coordinates: [-77.41369, 35.603806].
    Updated: Feb 25
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    Move-in Ready Greenville Office Spaces
    $500/Mo
    Move-in Ready Greenville Office Spaces

    404 St Andrews Drive, Greenville, NC 27834

    Individual office spaces available for lease with all-inclusive amenities.
    • Move‑in ready individual office spaces with flexible lease options. Choose a window or interior office to suit your needs and budget.
    • All‑inclusive amenities simplify budgeting and operations. Enjoy utilities, high‑speed internet, trash, and common area janitorial services.
    • Convenient central location provides easy access to major roadways, downtown, shopping, and dining.
    • Shared conference room and furnished break rooms offer professional meeting and relaxation spaces.
    • Ample on‑site parking ensures convenient access for tenants and clients.
    Updated: Jul 31, 2025
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    Move-in Ready Office Space Available
    $2,800/Mo
    1,730 SF
    Move-in Ready Office Space Available

    Office space for lease with all-inclusive amenities in Greenville.

    404 St Andrews Drive, Greenville, NC 27834

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    Move-in Ready Office Space Available
    $2,850/Mo
    1,510 SF
    Move-in Ready Office Space Available

    Office space for lease in Greenville, NC with all-inclusive amenities.

    404 St Andrews Drive, Greenville, NC 27834

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    Move-in Ready Office Space Available
    $2,850/Mo
    1,575 SF
    Move-in Ready Office Space Available

    Well-maintained commercial property with flexible office options in Greenville, NC.

    404 St Andrews Drive, Greenville, NC 27834

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    Move-in Ready Office Space Available
    $2,900/Mo
    1,945 SF
    Move-in Ready Office Space Available

    Well-maintained office complex with flexible options and all-inclusive amenities.

    404 St Andrews Drive, Greenville, NC 27834

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    Move-in Ready Office Space Available
    $2,900/Mo
    1,775 SF
    Move-in Ready Office Space Available

    Well-maintained office complex with flexible leasing options and all-inclusive amenities.

    404 St Andrews Drive, Greenville, NC 27834

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    Remodeled Office Suites in Greenville
    $15 SF/Yr
    2,635 SF
    Remodeled Office Suites in Greenville

    Completely remodeled office suites in the heart of Greenville.

    2408 S Charles Blvd, Greenville, NC 27858

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    Medical Office Suite For Rent
    $18 SF/Yr
    1,755 SF
    Medical Office Suite For Rent

    1,755 SF medical office suite in a desirable location.

    1011 WH Smith Blvd, Greenville, NC

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    Functional Office Space in Greenville
    $1,500/Mo
    900 SF
    Functional Office Space in Greenville

    900 SF office suite with reception and private offices.

    3105 S Evans St, Greenville, NC

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    Professional Office Space in Greenville
    $13 SF/Yr
    1,705 SF
    Professional Office Space in Greenville

    Conveniently located office space near ECU and ECU Health.

    612 Country Club Dr, Greenville, NC

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    Medical Office Building with Exam Rooms
    Contact for pricing
    17,583 SF
    Medical Office Building with Exam Rooms

    Purpose-built medical layout with exam, procedure, and ultrasound rooms plus on-site parking for patient visits and daily operations.

    2251 Stantonsburg Rd, Greenville, NC 27834

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    Medical Office Space Available
    Contact for pricing
    1,852 SF
    Medical Office Space Available

    Class B office space configured for medical use.

    1970 West Arlington Boulevard, Greenville, NC 27834

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    Move-in Ready Office or Retail
    Contact for pricing
    1,200 SF
    Move-in Ready Office or Retail

    1,200 sqft space ideal for office, retail, or medical use.

    803 Moye Boulevard, Greenville, NC 27834

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    Office and Flex Space Available
    $18 SF/Yr
    4,325 SF
    Office and Flex Space Available

    Office and warehouse/flex space near Greenville for lease.

    4597 US-264, Greenville, NC 27834

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    Downtown Retail or Office Space
    $12 SF/Yr
    4,476 SF
    Downtown Retail or Office Space

    Prime downtown Greenville retail or office space for rent.

    416 Evans St, Greenville, NC

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    Professional Office Building in Greenville
    Contact for pricing
    13,276 SF
    Professional Office Building in Greenville

    Two-story office building in Greenville's Medical District for lease.

    2217 Stantonsburg Rd, Greenville, NC 27835

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    Retail Space on Greenville Boulevard
    Contact for pricing
    4,100 SF
    Retail Space on Greenville Boulevard

    Prime retail leasing opportunity in Greenville's commercial corridor.

    611 Greenville Blvd SE, Greenville, NC 27858

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    Medical Office Space For Rent
    $18 SF/Yr
    10,146 SF
    Medical Office Space For Rent

    Medical office space in a major medical district.

    400 Spring Forest Rd, Greenville, NC

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    Medical Office Near ECU Health
    $15 SF/Yr
    4,711 SF
    Medical Office Near ECU Health

    Medical office space available across from ECU Health's Medical Center.

    2269 Stantonsburg Rd, Greenville, NC

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    Greenville Office Space For Rent
    Contact for pricing
    Greenville Office Space For Rent

    Professional office suite in high-traffic Greenville corridor, available 2026.

    3535 S Memorial Dr, Greenville, NC 27834

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    Office Space Available For Rent
    Contact for pricing
    410 SF
    Office Space Available For Rent

    Office space available, approximately 410 square feet.

    1528 Evans St, Greenville, NC 27834

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    Mixed-Use Space in Downtown Greenville
    Contact for pricing
    4,626 SF
    Mixed-Use Space in Downtown Greenville

    Versatile 4,626 sq ft space in a vibrant location.

    306 E 10th St, Greenville, NC 27858

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    Premier Mixed-Use Property in Uptown
    Contact for pricing
    2,999 SF
    Premier Mixed-Use Property in Uptown

    Retail, restaurant, or office spaces in Greenville's vibrant Uptown District.

    630 Cotanche Street, Greenville, NC 27858

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    Greenville, NC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Greenville, NC with 25 listings featured on our commercial real estate exchange. The current inventory includes 40,588 square feet of properties with an estimated lease value of $284 SF/Yr.

    Estimated lease rates for Office Spaces in Greenville, NC begin at $12 SF/Yr, with an average of $18 SF/Yr and extend to $40 SF/Yr.
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    Most Searched ZIP Codes in Greenville, NC

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