Topsham, ME Office Spaces for Rent & Lease

Updated: Nov 24, 2025

Topsham Medical/Office Space Available

105 Topsham Fair Mall Road, Topsham, ME 04086

$20 SF/Yr

Anchored by Central Maine Healthcare and New England Cancer Center.
Prime medical/office space with 7,633+/- SF.
Easy access to and visible from I‑295.
Newly renovated medical center.
High traffic count: 14,090 vehicles/day (AADT 2019).

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 1 Active listings in Topsham, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Renovated Downtown Office Units

5 Depot St, Freeport, ME 04032

$16 SF/Yr

3,174 sqft

Updated commercial workspace is available in downtown Freeport.

View details

Office Space with Dock Doors

21 Westminster Street, Lewiston, ME 04240

Contact for pricing

3,117 sqft

Flexible commercial space with parking and access to major regional transportation routes.

View details

Configurable Office Units

13 Westminster Street, Lewiston, ME 04240

Contact for pricing

2,000 sqft

Office space offers flexible configuration and ample parking within an established business park setting.

View details

Main Street Office Building For Rent

135 Main Street, Freeport, ME 04032

Contact for pricing

4,590± SF office building on heavily trafficked Main Street.

View details

Similar Spaces for Sale in Topsham, ME

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Office Building with Private Yard

62 Main Street, Topsham, ME 04086

$450,000

1,649 sqft 0.66 AC lot

Occupied professional office property with a flexible layout, off-street parking, and public water and sewer.

View details

Leased Office Units with Private Backyard

62 Main Street, Topsham, ME 04086

$450,000

1,649 sqft 0.66 AC lot

Configured as professional office space with a private backyard, leased through January 2027, with three office rooms and two bathrooms.

View details

Mixed-Use Property with Lakefront Setting

32 Sky-Hy Drive, Topsham, ME 04086

$1,195,000

21,844 sqft 21.00 AC lot

Multi-level facility with conference, office, living, and meeting spaces for varied commercial and institutional uses.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Waterfront Land with River Frontage

Riverside Drive, Augusta, ME 04330

Contact for pricing

72.00 AC lot

Lease area is served by public water and public sewer.

View details

Topsham, ME Office Spaces Lease Rates & Market Statistics

Browse 1 Office Spaces listing for lease in Topsham, ME on Realmo, a commercial real estate marketplace serving the Topsham area.

Asking lease rates for Office Spaces in Topsham start at $20 SF/Yr, average $20 SF/Yr, and reach $20 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $20 SF/Yr is 15% above the Maine state average of $17.35 SF/Yr.

Topsham accounts for 100% of the 1 office spaces listing currently available across Sagadahoc County.

Topsham, ME Office Spaces for Lease

105 Topsham Fair Mall Road, Topsham, ME 04086