Topsham, ME Medical Office Space for Rent & Lease

Updated: Nov 24, 2025

Topsham Medical/Office Space Available

105 Topsham Fair Mall Road, Topsham, ME 04086

$20 SF/Yr

Anchored by Central Maine Healthcare and New England Cancer Center.
Prime medical/office space with 7,633+/- SF.
Easy access to and visible from I‑295.
Newly renovated medical center.
High traffic count: 14,090 vehicles/day (AADT 2019).

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Based on your search, we've compiled 5 Potential Opportunities for your consideration. Besides 1 Active listings in Topsham, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Freestanding Retail Building with Exam Rooms

185 Ocean St, South Portland, ME 04106

$24 SF/Yr

8,125 sqft

Freestanding retail building with a current buildout of 16 private exam rooms in a high-visibility area.

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Turnkey Medical Office Suite

94 Washington Avenue, Portland, ME 04101

$1,800/Mo

Fully furnished dental-medical suite with treatment rooms, office, and reception, plus on-site parking for non-profit users.

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Medical Office Suite with Exam Rooms

10 Q St, South Portland, ME 04106

Contact for pricing

2,250 sqft

Prime medical office space with exam rooms, waiting area, and full handicap accessibility.

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Retail/Office Space on Marginal Way

191 Marginal Way, Portland, ME 04101

$38 SF/Yr

Retail/office space in a mixed-use building with high visibility.

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Topsham, ME Medical Office Space Lease Rates & Market Statistics

Browse 1 Medical Office Space listing for lease in Topsham, ME on Realmo, a commercial real estate marketplace serving the Topsham area.

Asking lease rates for Medical Office Space in Topsham start at $20 SF/Yr, average $20 SF/Yr, and reach $20 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $20 SF/Yr is 23% below the Maine state average of $26.03 SF/Yr.

Topsham accounts for 100% of the 1 medical office space listing currently available across Sagadahoc County. Medical Office Space is one of the more limited space types in Topsham, with just 1 listing currently available — a scarcity worth factoring into lease negotiations.

Topsham, ME Medical Office Space for Lease

105 Topsham Fair Mall Road, Topsham, ME 04086