Safety Harbor, FL Office Spaces for Rent & Lease

Updated: Apr 11, 2025

Office Suites with Private Offices

670 2ND Street N, Safety Harbor, FL 34695

$30 SF/Yr

3,498 sqft 0.17 AC lot

Suite B offers 973 square feet, a reception area, and three private offices
Suite D provides 770 square feet and two private offices
Each suite has a private restroom and dedicated on‑site parking
GO zoning; 1998 construction with block exterior and central air

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Updated: Sep 14

Office Unit with Private Office

500 MAIN ST #J, Safety Harbor, FL 34695

$2,000/Mo

21,348 sqft

Approximately 1,000 square feet in Unit J
Private office with a window and handicap‑accessible restroom
New neutral paint and durable vinyl flooring
Elevator access, two stairways, and front and rear balconies
Private parking lot behind the building plus free city parking

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Safety Harbor Office Suites Available

670 2ND St N, Safety Harbor, FL 34695

Contact for pricing

1,526 sqft 0.17 AC lot

Office suites available for lease in Safety Harbor, Florida.

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Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 3 Active listings in Safety Harbor, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Class A Medical Office Space

St Petersburg, FL

Contact for pricing

2,641 sqft 3.52 AC lot

Upscale medical office building near hospitals and downtown St. Petersburg.

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Elevator-Entry Office Suite

3000 Gulf to Bay Blvd, 601, Clearwater, FL 33759

Contact for pricing

The mostly private office layout includes an abundance of natural light and views.

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Class A Office Space Available

2605 Enterprise Rd E, Clearwater, FL

Contact for pricing

2,685 sqft 5.84 AC lot

Premium office space in a vibrant submarket, near US-19.

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Furnished Medical Suite Co-Lease

302-1201 5th Ave N, St Petersburg, FL 33701

Contact for pricing

300 sqft

Co-lease two furnished exam rooms on the 3rd floor of a hospital professional building, with utilities included.

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Similar Spaces for Sale in Safety Harbor, FL

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Medical Office with Private Offices

108 4th Ave S, Safety Harbor, FL 34695

$1,299,000

3,812 sqft 0.16 AC lot

The downtown building includes a reception area, conference room, kitchen, and entrances on its east and west sides.

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Two-Building Retail and Office Property

135 4TH AVENUE N, Safety Harbor, FL 34695

$1,350,000

2,120 sqft

Two connected buildings include a front cottage storefront and a rear art studio with separate entrances and interior hallway access.

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Medical Office Building

108 4TH S, Safety Harbor, FL 34695

$1,299,000

3,812 sqft 0.16 AC lot

A downtown professional layout pairs multiple work areas with a conference room and entrances on opposite sides of the building.

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Safety Harbor Office For Sale

801 2ND STREET N C, Safety Harbor, FL 34695

$430,000

1,202 sqft

Office space available in Safety Harbor, Florida.

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Medical Office with Private Offices

108 4TH Avenue S, Safety Harbor, FL 34695

$1,299,000

3,812 sqft 0.16 AC lot

A reception area, conference room, kitchen, and multiple restrooms support the building’s current medical-office arrangement.

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Live-Work Redevelopment Lot with Addition

734 2nd St N, Safety Harbor, FL 34695

Contact for pricing

1,200 sqft

Residential or commercial zoning plus an existing home and unfinished addition support a flexible redevelopment or live-work buildout.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Near Signalized Intersection

2305 N NEBRASKA Avenue, Tampa, FL 33602

$6,000/Mo

0.45 AC lot

Commercial land with YC-5 zoning, public utilities, and access to established Tampa corridors.

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Safety Harbor, FL Office Spaces Lease Rates & Market Statistics

Browse 3 Office Spaces for lease in Safety Harbor, FL on Realmo, a commercial real estate marketplace serving the Safety Harbor area. The current inventory totals 26,372 square feet of properties.

Office Spaces lease rates in Safety Harbor range from $1.12 SF/Yr at the entry level to $30 SF/Yr at the top of the market, averaging $15.56 SF/Yr. That's a 27x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $15.56 SF/Yr, the local average runs 55% below Florida's state average of $34.82 SF/Yr.

Safety Harbor accounts for 1% of the 237 office spaces currently available across Pinellas County, where nearby markets include St Petersburg and Clearwater.