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    St Petersburg, FL Medical Office Space for Lease

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    Gulfport, FL South Pasadena, FL Pinellas Park, FL
    16 results
    Corner Office Suite in St. Petersburg
    $23 SF/Yr
    1,415 SF

    Corner Office Suite in St. Petersburg

    5001 4TH STREET N, St Petersburg, FL 33703

    Spacious suite ideal for offices, medical, spa, or salon.

    • High‑visibility corner location in a dynamic St. Petersburg neighborhood.
    • Functional layout includes reception area, waiting room, conference room, and ADA‑compliant restroom.
    • Landlord assistance with build‑out costs to customize the interior.
    • Abundant natural light in the conference room due to large windows on two sides.
    • Flexible open layout suitable for various business configurations.
    Updated: Mar 25, 2025
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    Medical/Professional Office Space Available
    $15 SF/Yr
    1,378 SF

    Medical/Professional Office Space Available

    1212-1216 66th St N, Saint Petersburg, FL

    Office suites available in a high-visibility Pinellas County location.

    • Highly visible location on busy 66th Street North in Pinellas County.
    • Medical/professional office center.
    • Ample parking with 44 spaces.
    • Two suites available: 1,795 SF (former chiropractic office) and 1,378 SF (large open space).
    • Single‑story building with 7 tenants.
    Updated: Nov 24, 2025
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    St. Petersburg Office Space Available
    $20 SF/Yr
    7,104 SF

    St. Petersburg Office Space Available

    Office suites for rent on 66th Street North, St. Petersburg.

    Saint Petersburg, FL 33710
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    Medical/Office Space For Rent
    $19 SF/Yr
    1,379 SF

    Medical/Office Space For Rent

    Medical or office suites available with recent renovations and included services.

    5800 49th Ave N, St Petersburg, FL
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    Available Office Space Near Hospital
    $22 SF/Yr
    2,111 SF

    Available Office Space Near Hospital

    2,111 SF office space near St. Petersburg General Hospital.

    5747 38th Ave N, Saint Petersburg, FL
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    St. Petersburg Office Space Available
    $142,080 SF/Yr
    7,104 SF

    St. Petersburg Office Space Available

    Office suites for lease with dedicated parking and signage.

    1234-1238-1240-1224 66th St N, St Petersburg, FL 33710
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    St. Petersburg Medical Office Space
    Contact for pricing
    1,400 SF

    St. Petersburg Medical Office Space

    Warm shell, build-to-suit space in high-traffic medical complex.

    St Petersburg, FL 33710
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    Medical Office Space on Gulf Boulevard
    Contact for pricing

    Medical Office Space on Gulf Boulevard

    Established medical facility in prime St. Pete Beach location.

    6455 Gulf Blvd, St Pete Beach, FL 33706
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    Suburban Office Building Near Hospital
    Contact for pricing
    1,700 SF

    Suburban Office Building Near Hospital

    Six-story office building suitable for professional or medical use.

    2600 Dr Martin Luther King Jr St N, Saint Petersburg, FL
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    St. Petersburg Office Space Available
    $142,080 SF/Yr

    St. Petersburg Office Space Available

    Office suites for lease with dedicated parking and signage.

    Saint Petersburg, FL 33710
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    Freestanding Medical Office Sublease
    Contact for pricing
    10,109 SF

    Freestanding Medical Office Sublease

    10,109 SF medical office space for sublease in St. Petersburg.

    St Petersburg, FL 33713
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    St. Petersburg Office/Medical Space
    Contact for pricing

    St. Petersburg Office/Medical Space

    Centrally located office or medical space for lease.

    St Petersburg, FL 33710
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    Class A Medical Office Space
    Contact for pricing
    2,641 SF

    Class A Medical Office Space

    Upscale medical office building near hospitals and downtown St. Petersburg.

    St Petersburg, FL
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    Medical/Retail Space For Rent
    Contact for pricing

    Medical/Retail Space For Rent

    Established medical and retail corridor with high visibility.

    St Petersburg, FL 33710
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    Medical Office Space Downtown St.
    Contact for pricing
    2,847 SF

    Medical Office Space Downtown St.

    Prime downtown location near hospitals, ideal for healthcare professionals.

    501 Dr Martin Luther King Jr St S, Saint Petersburg, FL
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    Downtown St. Petersburg Retail Space
    $30 SF/Yr

    Downtown St. Petersburg Retail Space

    Located in the heart of Downtown St. Petersburg.

    St Petersburg, FL 33701
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    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 16 Active listings in St Petersburg, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Move-in Ready Largo Office Space
    $19 SF/Yr
    37,000 SF

    Move-in Ready Largo Office Space

    Commercial office and medical space available for lease in Largo.

    11350 66TH STREET, Largo, FL 33773
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    Functional Office Space in Pinellas
    $12 SF/Yr

    Functional Office Space in Pinellas

    Former dental office suitable for medical or veterinary practice.

    4930 PARK Blvd N 1, Pinellas Park, FL 33781
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    Move-in Ready Commercial Office Space
    Contact for pricing
    6,000 SF

    Move-in Ready Commercial Office Space

    Available for lease in Pinellas County. Suites from 800-6,000sqft.

    11380 66th Street North, Largo, FL 33773
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    Gandy Center3491 Gandy Blvd
    $19 SF/Yr

    Gandy Center3491 Gandy Blvd

    1,040 - 27,402 SF of Space Available in Pinellas Park, FL 33781

    3491 Gandy Blvd, Pinellas Park, FL 33781, Pinellas Park, FL 33781
    View details

    Similar Spaces for Sale in St Petersburg, FL

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    Turnkey Medical Office in St. Petersburg
    $920,000
    2,496 SF
    Turnkey Medical Office in St. Petersburg

    Fully built-out medical office with flexible layout and ample parking.

    1152 62ND AVENUE S, St Petersburg, FL 33705

    View details
    Turnkey Medical and Wellness Facility
    $2,400,000
    5,784 SF
    Turnkey Medical and Wellness Facility

    Professionally outfitted health center in a booming St. Petersburg area.

    1700 DR MARTIN LUTHER KING JR STREET N, St Petersburg, FL 33704

    View details
    Turnkey Medical Office in St. Petersburg
    $920,000
    2,496 SF
    Turnkey Medical Office in St. Petersburg

    Fully built-out medical office ready for new owners/users.

    1152 62ND AVENUE S, St Petersburg, FL 33705

    View details
    St Pete Medical Office Opportunity
    $1,999,000
    6,220 SF
    St Pete Medical Office Opportunity

    Two medical office buildings totaling 6,220 SF on 0.5+ acre.

    1701-1799 66TH N STREET, St Petersburg, FL 33710

    View details
    Well-Maintained Office Building For Sale
    $939,000
    2,750 SF
    Well-Maintained Office Building For Sale

    Three-unit office building near Publix, suitable for investment or owner-occupancy.

    6967 SUNSET DRIVE S, St Petersburg, FL 33707

    View details
    Boutique Medical and Aesthetic Suite
    $1,550,000
    1,472 SF
    Boutique Medical and Aesthetic Suite

    Fully leased medical property with income and upside potential.

    2200 49TH STREET N, St Petersburg, FL 33710

    View details
    Central Avenue Professional Office/Apartment
    $895,000
    2,804 SF
    Central Avenue Professional Office/Apartment

    Professional office with apartment near downtown and beaches.

    5621 CENTRAL AVENUE, St Petersburg, FL 33710

    View details
    Two-Story Office Building on Central
    $2,300,000
    5,168 SF
    Two-Story Office Building on Central

    Freestanding two-story office building with elevator and ample parking.

    4701 CENTRAL AVENUE, St Petersburg, FL 33713

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
    View details

    St Petersburg, FL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in St Petersburg, FL with 16 listings featured on our commercial real estate exchange. The current inventory includes 20,491 square feet of properties with an estimated lease value of $142,179.

    Estimated lease rates for Medical Office Space in St Petersburg, FL begin at $15 SF/Yr, with an average of $23,696 and extend to $142,080.
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