Medical Space

St Petersburg, FL Medical Office Space for Lease

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33 properties
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Four-Unit Flex Space
Updated: Apr 8, 2025
Four-Unit Flex Space

4200 CENTRAL Avenue S, St Petersburg, FL 33711

$20 SF/Yr
8,681 sqft 0.55 AC lot
Four separate units: three 1,000‑square‑foot suites plus one 3,000‑square‑foot suite
8,681 square feet on a 0.55‑acre lot
Every unit includes a separate electric meter and individual bathroom
3,000‑square‑foot unit was formerly configured as a doctor’s office
Block and stucco construction with central air
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Freestanding Medical Office Building
Updated: Aug 17
Freestanding Medical Office Building

2555 Pinellas Point Dr S, St Petersburg, FL 33706

$32 SF/Yr
3,196 sqft 1.11 AC lot
Approximately 3,196± SF medical office building on a 1.11± acre site
Freestanding one‑story masonry construction completed in 2006
Veterinary clinic layout with reception, waiting, exam, treatment, office, restroom, and support areas
Located at 2555 Pinellas Point Dr S, St Petersburg, FL 33706
Access to Interstate 275, Downtown St. Petersburg, and the Skyway Bridge
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Pediatric Medical Office Suite
Pediatric Medical Office Suite

St Petersburg, FL 33701

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3,704 sqft

Configured with clinical rooms, administrative offices, reception, and shared building amenities for an established healthcare operation.

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Ground-Floor Office and Medical Suites
Ground-Floor Office and Medical Suites

St Petersburg, FL 33709

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2,600 sqft

Move-in-ready ground-floor office/medical suites with on-site parking and convenient access.

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Medical Office Sublease
Medical Office Sublease

St Petersburg, FL 33705

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4,529 sqft

Medical suite available under a sublease extending through February 2028.

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Freestanding Medical Office Sublease
Freestanding Medical Office Sublease

St Petersburg, FL 33713

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10,109 sqft

10,109 SF medical office space for sublease in St. Petersburg.

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Medical Pavilion Lease Space
Medical Pavilion Lease Space

St Petersburg, FL 33701

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12,062 sqft

Specialized healthcare space within a tertiary academic medical center and Level II Adult & Pediatric Trauma Center.

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Office and Medical Suite Building
Office and Medical Suite Building

St Petersburg, FL 33709

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1,850 sqft

Ground-floor suites range from about 1,350 to 2,600 SF, with select space combinable up to approximately 5,800 SF.

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Office Unit in Six-Story Building
Office Unit in Six-Story Building

2600 Dr Martin Luther King Jr St N, Saint Petersburg, FL 33704

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3,713 sqft

Office unit supporting professional, medical, dental, or law office use.

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Ground-Floor Office and Medical Suites
Ground-Floor Office and Medical Suites

St Petersburg, FL 33709

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1,450 sqft

Ground-floor office and medical suites from 1,350 to 2,600 SF, featuring move-in-ready layouts, on-site parking, and strong visibility.

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Ground-Floor Office Units
Ground-Floor Office Units

St Petersburg, FL 33709

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1,350 sqft

Move-in-ready suites offer on-site parking, prominent signage, and convenient access for professional service users.

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Furnished Medical Office Suite
Furnished Medical Office Suite

1201 FIFTH AVE N #302, St Petersburg, FL 33715

$1,296-$1,944/Mo
300 sqft

Third-floor shared medical suite with furnished rooms, exam areas, a generous waiting room, and included utilities.

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Medical Office Near Bayfront Hospital
Medical Office Near Bayfront Hospital

St Petersburg, FL 33701

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3,704 sqft 0.68 AC lot

Medical office space for lease near Bayfront and All Children's.

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Hospital Medical Pavilion
Hospital Medical Pavilion

St Petersburg, FL 33701

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21,009 sqft

Healthcare-oriented space within a 480-bed tertiary academic medical center in downtown St. Petersburg.

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Turnkey Medical Office Suite
Turnkey Medical Office Suite

St Petersburg, FL 33710

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2,000 sqft 0.28 AC lot

Turnkey medical space with exam rooms, X-ray room, and lab setup, plus 15 parking spaces and immediate availability.

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Class A Medical Office Building
Class A Medical Office Building

St Petersburg, FL 33701

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710 sqft

Five-story Class A medical office building with an upscale lobby, in-building café, and on-site security and property management.

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Two-Story Office Building with Suite
Two-Story Office Building with Suite

St Petersburg, FL 33704

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649 sqft 1.62 AC lot

Highly visible two-story office building with a second-floor office suite and atrium lobby.

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Private Medical Office Room
Private Medical Office Room

Saint Petersburg, FL 33710

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188 sqft

Private treatment room with connected storage, shared client amenities, utilities included, and access to on-site parking.

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Medical Office Sublease Suite
Medical Office Sublease Suite

St Petersburg, FL 33713

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3,711 sqft

Second-floor medical suite includes five exam rooms, three in-suite restrooms, and multiple private offices.

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Five-Story Medical Office Building with Cafe
Five-Story Medical Office Building with Cafe

St Petersburg, FL 33701

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755 sqft

Five-story Class A medical office with an in-building cafe, valet parking, and connected public access to nearby Bayfront Health.

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Medical Office Space For Lease
Medical Office Space For Lease

St Petersburg, FL 33710

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1,400 sqft 0.72 AC lot

1,400 SF warm shell space in high-traffic medical complex.

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Class A Medical Office Space
Class A Medical Office Space

St Petersburg, FL

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2,641 sqft 3.52 AC lot

Upscale medical office building near hospitals and downtown St. Petersburg.

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Six-Story Office Building
Six-Story Office Building

2600 Dr Martin Luther King Jr St N, Saint Petersburg, FL 33704

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1,700 sqft

Six-story suburban office building offering professional and medical/dental or law office space.

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Suburban Office Building Near Hospital
Suburban Office Building Near Hospital

2600 Dr Martin Luther King Jr St N, Saint Petersburg, FL

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1,700 sqft 1.21 AC lot

Six-story office building suitable for professional or medical use.

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St Petersburg, FL Medical Office Space Lease Rates & Market Statistics

Explore 33 Medical Office Space listings for lease in St Petersburg, FL on Realmo, a commercial real estate exchange covering the St Petersburg area. The current inventory totals 115,168 square feet of properties — an average of ~3,500 SF per listing.

Medical Office Space lease rates in St Petersburg range from $20 SF/Yr at the entry level to $103.68 SF/Yr at the top of the market, averaging $58.36 SF/Yr. That's a 5x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $58.36 SF/Yr, the local average runs 103% above Florida's state average of $28.76 SF/Yr.

St Petersburg accounts for 32% of the 102 medical office space listings currently available across Pinellas County, where nearby markets include Largo and Clearwater. Medical Office Space listings make up 22% of the 151 Office Spaces currently for lease in St Petersburg, with asking rates averaging $58.36 SF/Yr — 65% above the citywide Office Spaces average of $35.41 SF/Yr. Tenants comparing options may also consider Office Units (81 listings) and Office buildings (51 listings) elsewhere in the St Petersburg market.

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