Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Palmetto, FL Office Properties & Spaces for Lease

    Notify Me
    List
    Map
    Stand Alone Building For Lease
    $18 SF/Yr
    2,640 SF

    Stand Alone Building For Lease

    1331 10th St E, Palmetto, FL

    Stand-alone building suitable for office, medical, or retail use.

    • Stand‑alone building: Only stand‑alone building in River North Business Center.
    • Flexible zoning: CG zoning designation suitable for office, medical, or retail use.
    • Ample parking: Abundance of parking spaces available for customers and employees.
    • Functional floorplan: Includes 10 private offices, reception area, open area, kitchenette, and 2 handicap restrooms.
    • Strategic location: Located between US 41/Business 41 and I‑75, with easy access to I‑275.
    Updated: Oct 28, 2025
    View details
    Renovated Building on US41/US19 Interchange
    Contact for pricing

    Renovated Building on US41/US19 Interchange

    3966 U.S. 41, Palmetto, FL

    Modernized freestanding building suitable for retail, restaurant, or offices.

    • Prime, highly visible location at the US41 and US19 interchange with high traffic exposure.
    • Completely renovated and modernized building suitable for retail, restaurant, or office use.
    • Ample parking and storage space.
    • All new plumbing, sewer, and electrical systems within the last 7 years.
    • Includes a 26kw generator and (3) full RV hook‑ups.
    Updated: Nov 25, 2025
    View details
    Palmetto Retail/Flex Space Available
    Contact for pricing
    2,240 SF

    Palmetto Retail/Flex Space Available

    Versatile 2,240 SF retail/flex space in Palmetto, Florida.

    925 10th St E, Palmetto, FL 34221
    View details
    Riverfront Office Space Available
    Contact for pricing

    Riverfront Office Space Available

    Renovated office space with river views in Palmetto, Florida.

    1001 Riverside Dr, Palmetto, FL 34221
    View details
    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 4 Active listings in Palmetto, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space Near Hospital
    $24 SF/Yr
    900 SF

    Medical Office Space Near Hospital

    Medical office suites available near Manatee Memorial Hospital in Bradenton.

    201 4th Ave E, Bradenton, FL 34208
    View details
    Class A Riverfront Office Space
    $14 SF/Yr
    5,871 SF

    Class A Riverfront Office Space

    Premier office space with Manatee River views and convenient access.

    101 Riverfront Blvd, Bradenton, FL
    View details
    Professional Office Building in Riverwalk
    Contact for pricing
    2,070 SF

    Professional Office Building in Riverwalk

    Well-maintained office building near Manatee Memorial Hospital.

    100 3rd Ave W, Bradenton, FL
    View details
    Medical Office Space Near Hospital
    $35 SF/Yr
    5,795 SF

    Medical Office Space Near Hospital

    Class A medical space available near Manatee Memorial Hospital.

    401 Manatee Avenue E, Bradenton, FL
    View details

    Explore Similar Spaces for Sale in Palmetto, FL

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    High-Visibility Land on Moccasin Wallow
    $1,399,999
    1,080 SF

    High-Visibility Land on Moccasin Wallow

    2.49 acre parcel with road frontage in rapidly growing area.

    2519 MOCCASIN WALLOW ROAD, Palmetto, FL 34221
    View details
    Downtown Palmetto Commercial Property
    $699,000
    4,600 SF

    Downtown Palmetto Commercial Property

    Two-story commercial property with retail and office space.

    435 10th Ave W, Palmetto, FL
    View details
    Palmetto Medical Building on 2.24 Acres
    $2,790,000
    16,382 SF

    Palmetto Medical Building on 2.24 Acres

    Strategically located medical building with flexible space and expansion potential.

    602 4th Avenue West, Palmetto, FL 34221
    View details
    High-Visibility Land on Moccasin Wallow
    $1,399,999
    1,080 SF

    High-Visibility Land on Moccasin Wallow

    2.5 acre parcel with road frontage in rapidly growing area.

    2519 MOCCASIN WALLOW ROAD, Palmetto, FL 34221
    View details
    High-Visibility Land on Moccasin Wallow
    $1,399,999
    2.49 Acres

    High-Visibility Land on Moccasin Wallow

    Prime ~2.5 acre parcel with road frontage in growing Parrish.

    2519 MOCCASIN WALLOW ROAD, Palmetto, FL 34221
    View details
    Palmetto Tower with Redevelopment Potential
    $6,000,000
    63,188 SF

    Palmetto Tower with Redevelopment Potential

    Multi-story office building with vacant lots in downtown Palmetto.

    600 W 8TH AVE, Palmetto, FL
    View details
    Free-Standing Industrial Facility For Sale
    $2,351,250
    12,375 SF

    Free-Standing Industrial Facility For Sale

    12,375 SF vacant industrial facility with showroom and warehouse space.

    1610 12th St E, Palmetto, FL 34221
    View details
    Versatile Retail and Office Center
    $1,750,000
    1,700 SF

    Versatile Retail and Office Center

    Retail and office center in downtown Palmetto, near Manatee River.

    701 8th Ave W, Palmetto, FL
    View details
    Palmetto Mixed-Use Development Opportunity
    $3,500,000
    3.40 Acres

    Palmetto Mixed-Use Development Opportunity

    Development site near Manatee River suitable for mixed-use projects.

    834 RIVERSIDE DRIVE, Palmetto, FL 34221
    View details
    Palmetto 52-Acre Assemblage Opportunity
    $10,500,000
    16,443 SF

    Palmetto 52-Acre Assemblage Opportunity

    52 acres with buildings, prime location, development potential.

    1321 77th St E, Palmetto, FL 34221
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land Lease Opportunity
    Contact for pricing

    Prime Land Lease Opportunity

    Land lease or build-to-suit opportunity in high-traffic location.

    120 Manatee Ave E, Bradenton, FL 34205
    View details
    Prime Commercial Corner Lot
    $30,000

    Prime Commercial Corner Lot

    Commercial land for rent in the heart of Bradenton.

    1614 9TH St W, Bradenton, FL 34205
    View details
    Commercial Parcel in Downtown Bradenton
    $2,500 /Mo
    520 SF

    Commercial Parcel in Downtown Bradenton

    Prime commercial land for rent in the heart of Bradenton.

    1614 9TH STREET W, Bradenton, FL 34205
    View details
    Commercial Land For Lease
    Contact for pricing

    Commercial Land For Lease

    Commercial land available for lease near major retailers.

    613 Cortez Rd W, Bradenton, FL
    View details

    Palmetto, FL Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Palmetto, FL with 4 listings featured on our commercial real estate exchange. The current inventory includes 114,998,400 square feet of properties with an estimated lease value of $18 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Palmetto, FL begin at $18 SF/Yr, with an average of $18 SF/Yr and extend to $18 SF/Yr.
    List
    Map

    Browse Office properties & Spaces for Lease Near Palmetto, FL

    Popular Searches in Palmetto, FL

    Popular Categories

    Most Searched ZIP Codes in Palmetto, FL

    • 34221

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!