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    Santa Maria, CA Office Spaces for Lease

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    16 properties
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    Second-Generation Retail & Medical Space
    Updated: Sep 3, 2025
    Second-Generation Retail & Medical Space

    345 Town Center W, Santa Maria, CA 93454

    Contact for pricing
    Second‑generation retail space in Town Center West Shopping Center, across from Town Center Mall
    Former Rite Aid tenant space with an expansive, open‑concept floor plan
    Future Heritage Walk Lofts project will add 104 loft‑style apartments in a connected former 85,900 SF building
    Suitable for retail, including large‑format apparel, home goods, discount stores, and sporting goods
    Suitable for medical uses such as urgent care, outpatient clinics, physical therapy, and large dental practices
    View details
    Turn-Key Building in Central Location
    Updated: Apr 24
    Turn-Key Building in Central Location

    135 Carmen Ln, Santa Maria, CA 93458

    $11,665/Mo
    3,280 sqft
    Turn‑key building in a central Santa Maria location with extensive renovations.
    Large parking lot with +30 spaces and ample street parking.
    Potential zoning modification to PD/C‑2 (Planned Development/General Commercial) expanding commercial/retail use possibilities.
    Building can be easily divided into two spaces, minimum divisible space is 3280 sq. ft.
    Easy access just off Broadway, a main thoroughfare.
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    Office and Warehouse Sublease
    Office and Warehouse Sublease

    2220 A Street, Santa Maria, CA 93455

    Contact for pricing
    8,411 sqft

    Sublease space includes a private office, restrooms, and a grade-level rollup door for flexible light-duty operations.

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    Single Tenant Office Space
    Single Tenant Office Space

    1467 Fairway Dr, Santa Maria, CA 93455

    $18 SF/Yr
    11,046 sqft

    Office space available for single tenant occupancy.

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    Fair Sky Park Office Suite
    Fair Sky Park Office Suite

    2601 Skyway Dr, Santa Maria, CA 93455

    $21 SF/Yr

    Office suite with private offices, conference room, and restrooms.

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    Updated Flex Warehouse with Roll-Ups
    Updated Flex Warehouse with Roll-Ups

    1131 Tama Lane, Santa Maria, CA 93455

    Contact for pricing
    3,800 sqft

    Updated flex warehouse with offices, HVAC, and multiple roll-up doors for flexible distribution and light industrial use.

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    Santa Maria Office Space Available
    Santa Maria Office Space Available

    3250 Skyway Dr, Santa Maria, CA 93455

    Contact for pricing
    5,812 sqft

    High-end office space in shell condition near Santa Maria Airport.

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    Santa Maria Office Space Available
    Santa Maria Office Space Available

    2353 S Broadway St, Santa Maria, CA 93454

    Contact for pricing
    1,270 sqft

    First floor office suites in professional building for lease.

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    Retail Space in Town Center
    Retail Space in Town Center

    345 Town Center West, Santa Maria, CA 93454

    Contact for pricing
    85,900 sqft

    Second-generation retail space in a busy shopping center.

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    Santa Maria Office Space Available
    Santa Maria Office Space Available

    3250 Skyway Dr, Santa Maria, CA

    Contact for pricing
    5,812 sqft

    Office spaces available from 1,000 to 5,812 square feet.

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    Stand-Alone Office Building For Rent
    Stand-Alone Office Building For Rent

    2353 S Broadway, Santa Maria, CA

    Contact for pricing
    1,253 sqft

    Stand-alone office building with on-site parking in Santa Maria.

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    Single-Tenant Retail/Office Building
    Single-Tenant Retail/Office Building

    528 S. Broadway, Santa Maria, CA 93454

    Contact for pricing

    Single-tenant building on Santa Maria’s South Broadway corridor with strong visibility, convenient access, and a large private parking lot.

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    Office Suite in Professional Building
    Office Suite in Professional Building

    222 CARMEN LN, Santa Maria, CA 93458

    Contact for pricing

    Lease a private office suite in a professional building with elevator service and ample parking.

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    Santa Maria Office Space Available
    Santa Maria Office Space Available

    2353 S Broadway St, Santa Maria, CA 93454

    Contact for pricing

    First floor office suites in professional building for lease.

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    Stand-Alone Office Building For Rent
    Stand-Alone Office Building For Rent

    302 CARMEN LN, Santa Maria, CA 93458

    Contact for pricing

    Single tenant office building with private parking lot.

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    Medical Office Space Available
    Medical Office Space Available

    525 Plaza Dr, Santa Maria, CA 93454

    Contact for pricing
    9,257 sqft

    Medical office suites available in Marian Medical Plaza.

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    Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 16 Active listings in Santa Maria, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class A Office Park with Highway Visibility
    Class A Office Park with Highway Visibility

    300 James Way, Pismo Beach, CA 93449

    Contact for pricing

    Class A office park offering highway visibility and a professional tenant mix, available for lease on NNN terms.

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    Class A Office Park Suite
    Class A Office Park Suite

    330 James Way, Pismo Beach, CA 93449

    Contact for pricing

    Class A office park with highway visibility, offering an NNN rental option in Pismo Beach.

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    Mixed-Use Building in Village Creek
    Mixed-Use Building in Village Creek

    200 Station Way C, Arroyo Grande, CA 93420

    Contact for pricing
    1,748 sqft

    Mixed-use building with medical/office space in Village Creek Promenade.

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    Arroyo Grande Office Space Available
    Arroyo Grande Office Space Available

    200 Station Way, Arroyo Grande, CA

    Contact for pricing
    1,748 sqft

    Office suite with exam rooms, private restroom, and patio.

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    Similar Spaces for Sale in Santa Maria, CA

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Converted Office Building with Parking
    Converted Office Building with Parking

    117 E Fesler Street, Santa Maria, CA 93454

    $695,000
    1,402 sqft 0.17 AC lot

    Converted residence offers private offices, a reception area, and onsite parking for client-facing professional services.

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    Medical Office Investment Opportunity
    Medical Office Investment Opportunity

    523 Barcellus Ave, Santa Maria, CA 93454

    $3,875,000
    4,335 sqft 0.51 AC lot

    Medical office building in Santa Maria, CA, fully leased.

    View details
    Mixed-Use Commercial Building
    Mixed-Use Commercial Building

    155 E Clark, Santa Maria, CA 93455

    $3,100,000
    7,516 sqft

    Modern 2021 office and commercial building with flexible space and a third-floor balcony for client-facing use.

    View details
    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    821 E Chapel St, Santa Maria, CA 93454

    $400,000
    1,306 sqft

    Well-appointed medical office suite with exam rooms, waiting and reception areas, and ample parking.

    View details
    Multi-Tenant Office/Industrial/Flex Building For Sale
    Multi-Tenant Office/Industrial/Flex Building For Sale

    2370 Skyway Dr, Santa Maria, CA 93455

    $3,350,000
    14,583 sqft 1.00 AC lot

    Fully leased investment opportunity in a thriving Central Coast market.

    View details
    Modern Dental Office Suite
    Modern Dental Office Suite

    426 Barcellus Ave, Santa Maria, CA 93454

    $649,000
    2,121 sqft

    Fully equipped dental suite in growing Santa Maria market.

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    Santa Maria Medical/Dental Office Building
    Santa Maria Medical/Dental Office Building

    504 E Church, Santa Maria, CA 93454

    $848,000
    3,342 sqft 0.18 AC lot

    Turnkey medical/dental office building in Santa Maria, California.

    View details
    Versatile Santa Maria Commercial Property
    Versatile Santa Maria Commercial Property

    3510 Black Rd, Santa Maria, CA 93455

    $6,900,000
    40,000 sqft 6.37 AC lot

    6.37 acre site with 40,000 SF in improvements.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Neighborhood Commercial Land for Development
    Neighborhood Commercial Land for Development

    2040 Prado Road, San Luis Obispo, CA 93401

    Contact for pricing

    Develop a neighborhood commercial site with retail, office, and medical uses, positioned for strong freeway visibility.

    View details
    Service Commercial Land For Rent
    Service Commercial Land For Rent

    1798 Hanford Armona Road, Hanford, CA 93230

    Contact for pricing

    3-acre service commercial land in high-traffic Hanford location.

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    High Visibility Land For Lease
    High Visibility Land For Lease

    1400 Willow Pass Rd, Concord, CA 94520

    Contact for pricing
    1 sqft

    1.41 acres at signalized intersection available for ground lease.

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    Build-to-Suit Corner Commercial Land
    Build-to-Suit Corner Commercial Land

    996 E 1st Avenue, Chico, CA 95926

    $5,000/Mo

    Corner commercial land with power onsite and city services on the street for a customizable build-to-suit project.

    View details

    Santa Maria, CA Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Santa Maria, CA with 16 listings featured on our commercial real estate exchange. The current inventory includes 21,391 square feet of properties with an estimated lease value of $65.18 SF/Yr.

    Estimated lease rates for Office Spaces in Santa Maria, CA begin at $2.00 SF/Yr, with an average of $16.30 SF/Yr and extend to $42.68 SF/Yr.
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    Most Searched ZIP Codes in Santa Maria, CA

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    • 93455
    • 93458

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