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    Santa Maria, CA
    Medical Space

    Santa Maria, CA Medical Office Space for Lease

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    Orcutt, CA Nipomo, CA Arroyo Grande, CA Pismo Beach, CA Grover Beach, CA Lompoc, CA San Luis Obispo, CA
    Second-Generation Retail & Medical Space
    Updated: Sep 3, 2025
    Second-Generation Retail & Medical Space

    345 Town Center W, Santa Maria, CA 93454

    Contact for pricing
    Second‑generation retail space in Town Center West Shopping Center, across from Town Center Mall
    Former Rite Aid tenant space with an expansive, open‑concept floor plan
    Future Heritage Walk Lofts project will add 104 loft‑style apartments in a connected former 85,900 SF building
    Suitable for retail, including large‑format apparel, home goods, discount stores, and sporting goods
    Suitable for medical uses such as urgent care, outpatient clinics, physical therapy, and large dental practices
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    Turn-Key Building in Central Location
    Updated: Apr 24
    Turn-Key Building in Central Location

    135 Carmen Ln, Santa Maria, CA 93458

    $11,665/Mo
    3,280 sqft
    Turn‑key building in a central Santa Maria location with extensive renovations.
    Large parking lot with +30 spaces and ample street parking.
    Potential zoning modification to PD/C‑2 (Planned Development/General Commercial) expanding commercial/retail use possibilities.
    Building can be easily divided into two spaces, minimum divisible space is 3280 sq. ft.
    Easy access just off Broadway, a main thoroughfare.
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    Retail Space in Town Center
    Retail Space in Town Center

    345 Town Center West, Santa Maria, CA 93454

    Contact for pricing
    85,900 sqft

    Second-generation retail space in a busy shopping center.

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    Medical Office Space Available
    Medical Office Space Available

    525 Plaza Dr, Santa Maria, CA 93454

    Contact for pricing
    9,257 sqft

    Medical office suites available in Marian Medical Plaza.

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 4 Active listings in Santa Maria, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Mixed-Use Building in Village Creek
    Mixed-Use Building in Village Creek

    200 Station Way C, Arroyo Grande, CA 93420

    Contact for pricing
    1,748 sqft

    Mixed-use building with medical/office space in Village Creek Promenade.

    View details
    Medical Office Suite with Patio
    Medical Office Suite with Patio

    200 Station Way, Arroyo Grande, CA 93420

    Contact for pricing
    1,748 sqft

    Suite C offers reception, nurse’s station, exam/physician offices, and a private outdoor patio.

    View details
    Medical Suite Near Highway 101
    Medical Suite Near Highway 101

    620 California G, San Luis Obispo, CA 93401

    Contact for pricing

    Medical suite available for rent near Highway 101.

    View details
    1288 Morro St, Suite 100
    1288 Morro St, Suite 100

    1288 Morro Street, Suite 100 | San Luis Obispo, CA 93401, San Luis Obispo, CA 93401

    Contact for pricing

    Medical Office | San Luis Obispo, CA

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    Similar Spaces for Sale in Santa Maria, CA

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Converted Residential Office Building
    Converted Residential Office Building

    117 E Fesler Street, Santa Maria, CA 93454

    $595,000
    1,402 sqft 0.17 AC lot

    Converted home with multiple private offices, reception area, and onsite parking in Santa Maria.

    View details
    Medical Office Investment Opportunity
    Medical Office Investment Opportunity

    523 Barcellus Ave, Santa Maria, CA 93454

    Contact for pricing
    4,335 sqft 0.51 AC lot

    Medical office building in Santa Maria, CA, fully leased.

    View details
    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    821 E Chapel St, Santa Maria, CA 93454

    Contact for pricing
    1,306 sqft

    Well-appointed medical office suite with exam rooms, waiting and reception areas, and ample parking.

    View details
    Multi-Tenant Office/Industrial/Flex Building For Sale
    Multi-Tenant Office/Industrial/Flex Building For Sale

    2370 Skyway Dr, Santa Maria, CA 93455

    Contact for pricing
    14,583 sqft 1.00 AC lot

    Fully leased investment opportunity in a thriving Central Coast market.

    View details
    Modern Dental Office Suite
    Modern Dental Office Suite

    426 Barcellus Ave, Santa Maria, CA 93454

    Contact for pricing
    2,121 sqft

    Fully equipped dental suite in growing Santa Maria market.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land for Long-Term Lease
    Commercial Land for Long-Term Lease

    5538 E Paisano Drive, El Paso, TX 79905

    $5,950/Mo

    Lease a C4-zoned lot with easy interstate access, suited for a range of business and professional uses.

    View details
    Office Development Land For Lease
    Office Development Land For Lease

    1323 Strawfloor Drive, Jonesboro, AR 72401

    Contact for pricing
    4,000 sqft

    2.43 acres for office development with build-to-suit opportunity.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details
    Prime Lexington Outlot Opportunity
    Prime Lexington Outlot Opportunity

    3330 Partner Place, Lexington, KY 40503

    Contact for pricing

    Outlot for ground lease or build-to-suit in South Lexington.

    View details

    Santa Maria, CA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Santa Maria, CA with 4 listings featured on our commercial real estate exchange. The current inventory includes 3,280 square feet of properties with an estimated lease value of $42.68 SF/Yr.

    Estimated lease rates for Medical Office Space in Santa Maria, CA average $42.68 SF/Yr.
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    Most Searched ZIP Codes in Santa Maria, CA

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    • 93458

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