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Cayce, SC Office Buildings for Lease

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Cayce Class A Office Space
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Cayce Class A Office Space

1300 12Th St, Cayce, SC 29033

Two-story office building with Class A space for rent.

  • Up to 5,555 square feet of Class A office space.
  • Convenient location with easy access to Columbia's Central Business District, Interstate 26, Columbia Metropolitan Airport, and the State Capitol Complex.
  • High‑speed internet connectivity with Cat 6 fiber optic cable availability.
  • Free parking adjacent to the building.
  • High‑traffic location on Knox Abbott Drive corridor (±28,000 vehicles per day).
Updated: Mar 12
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Cayce Office/Medical Space Available
$20 SF/Yr
5,670 SF

Cayce Office/Medical Space Available

1105 State St, Cayce, SC 29033

5,670 SF building suitable for office or medical use.

  • Large fenced parking lot
  • Ideal for professional or medical office use
  • ±5,670 SF one‑story building
  • ADA accessible
  • Walking distance to Guignard Park, pharmacy, grocery store and restaurants
Updated: Aug 8, 2025
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Based on your search, we've compiled 7 Potential Opportunities for your consideration. Besides 2 Active listings in Cayce, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Explore Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Elgin Office Space For Lease
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146,483 SF

Elgin Office Space For Lease

Office space available for lease in Elgin, South Carolina.

501 Spears Creek Church Rd, Columbia, SC
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Office Space Near Golf Club
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42,000 SF

Office Space Near Golf Club

Office building with convenient access and ample parking.

101 Research Ct, Columbia, SC
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Renovated Office Building Near Sunset
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4,000 SF

Renovated Office Building Near Sunset

Renovated 4,000 SF office building in Lexington County.

108 Tom Corley Pl, Lexington, SC
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New Class A Office Building
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New Class A Office Building

Class A office building for lease on W. Main Street.

322 W Main St, Lexington, SC 29072
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Explore Similar Spaces for Sale in Cayce, SC

Consider Similar Space for Sale. We found 1 Spaces in Nearby Locations matching your search parameters.

Office Building Near Downtown Columbia
$685,000
5,128 SF

Office Building Near Downtown Columbia

Office building with multiple suites, ideal for owner occupant.

1202 Indigo Ave, Cayce, SC 29033
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Cayce, SC Office buildings Leasing Opportunities Market Analysis

Explore Office buildings leasing options in Cayce, SC with 2 listings featured on our commercial real estate exchange. The current inventory includes 246,985,200 square feet of properties with an estimated lease value of $20 SF/Yr.

Estimated lease rates for Office buildings in Cayce, SC begin at $20 SF/Yr, with an average of $20 SF/Yr and extend to $20 SF/Yr.
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