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    Frederick, MD Office Buildings for Lease

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    Baltimore, MD Rockville, MD Columbia, MD
    8 results
    Stand-Alone Building in Frederick, MD
    $14 SF/Yr

    Stand-Alone Building in Frederick, MD

    6008 FAIR OAKS Drive, Frederick, MD 21703

    7,844 SF stand-alone building with second floor available for lease.

    • Stand‑alone 7,844 SF building on 0.68‑acre lot.
    • Income‑producing property with fully leased first floor.
    • ORI (Office Research Industrial) zoning.
    • Up to 12 parking spaces available.
    • 3‑Phase Electric Power.
    Updated: Jan 12
    View details
    Historic Downtown Frederick Office Space
    $20 SF/Yr

    Historic Downtown Frederick Office Space

    22 SECOND Street E, Frederick, MD 21701

    Charming office building in historic Downtown Frederick.

    • Prime location in historic Downtown Frederick.
    • Flexible configuration with up to seven individual offices across three levels.
    • Suitable for various professional uses (office, mental health, consulting, wellness).
    • Full kitchen for convenience.
    • Washer/dryer hookups for practicality.
    Updated: Nov 17, 2025
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    Renovated Commercial Space Available
    $213,480

    Renovated Commercial Space Available

    Premier commercial lease opportunity with recent renovations and high-end features.

    5301 Buckeystown Pike, Frederick, MD 21704
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    New Class A Office Space
    $22 SF/Yr
    8,000 SF

    New Class A Office Space

    Brand new Class A office building with flexible suite sizes.

    7100 Guilford Dr, Frederick, MD
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    Frederick Office Space Available
    Contact for pricing
    59,520 SF

    Frederick Office Space Available

    59,520 SF office space for rent in Frederick, MD.

    5275 Westview Dr, Frederick, MD
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    Class A Single Story Office
    Contact for pricing
    5,545 SF

    Class A Single Story Office

    Modern office building with convenient access and ample parking.

    4991 New Design Rd, Frederick, MD
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    Governors Place Medical Building Suites
    $23 SF/Yr
    25,000 SF

    Governors Place Medical Building Suites

    Class A medical building with flexible, customizable suite sizes.

    112 Thomas Johnson Dr, Frederick, MD
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    Frederick Office Space For Rent
    Contact for pricing
    82,205 SF

    Frederick Office Space For Rent

    82,205 square foot office building in Frederick, Maryland.

    5255 Westview Dr, Frederick, MD
    View details
    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 8 Active listings in Frederick, MD, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Office buildings for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Belward Campus Life Science Hub
    Contact for pricing
    1,500,000 SF

    Belward Campus Life Science Hub

    1.5 million sq ft campus for biotech trailblazers.

    9951 Key West Avenue, Rockville, MD 20850
    View details
    Class A Office Building
    Contact for pricing
    25,000 SF

    Class A Office Building

    Class A office building with flexible floor plans and amenities.

    15245 Shady Grove Rd, Rockville, MD
    View details
    Two-Story Building in Kentlands
    Contact for pricing
    19,364 SF

    Two-Story Building in Kentlands

    19,364 SF two-story building in downtown Kentlands, Gaithersburg.

    189 Kentlands Blvd, Gaithersburg, MD
    View details
    West Diamond Office Center Space
    Contact for pricing
    2,200 SF

    West Diamond Office Center Space

    Commercial office space for lease in Gaithersburg, Maryland.

    806 & 818 W. Diamond Ave, Gaithersburg, MD 20878
    View details

    Explore Similar Spaces for Sale in Frederick, MD

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Freestanding Office/Medical Building For Sale
    $3,250,000
    10,600 SF

    Freestanding Office/Medical Building For Sale

    10,600 SF office/medical building with parking and natural light.

    195 Thomas Johnson Dr, Frederick, MD 21702
    View details
    Historic Mixed-Use Property For Sale
    $1,350,000
    0.08 Acres

    Historic Mixed-Use Property For Sale

    Historic property with commercial and residential potential in Frederick, MD.

    110 N Court St, Frederick, MD 21701
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land at Major Intersection
    $400,000

    Commercial Land at Major Intersection

    8 acres of commercial land for ground lease.

    12640 Lord Fairfax Hwy, Boyce, VA 22620
    View details
    Commercial Land For Ground Lease
    $10,000 /Mo

    Commercial Land For Ground Lease

    Land available for ground lease in a high-traffic retail corridor.

    550 William Floyd Parkway, Shirley, NY 11967
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    Commercial Land on Montauk Highway
    $2,500 /Mo

    Commercial Land on Montauk Highway

    0.55-acre commercial lot on busy Montauk Highway.

    1467 Montauk Highway, Mastic, NY 11967
    View details
    Commercial Space on Trent Boulevard
    $1,200 /Mo
    1,000 SF

    Commercial Space on Trent Boulevard

    Versatile commercial space ready for customization in a prime location.

    3709 Trent Road, New Bern, NC 28562
    View details

    Frederick, MD Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Frederick, MD with 8 listings featured on our commercial real estate exchange. The current inventory includes 1,358,021,891 square feet of properties with an estimated lease value of $34 SF/Yr.

    Estimated lease rates for Office buildings in Frederick, MD begin at $14 SF/Yr, with an average of $17 SF/Yr and extend to $20 SF/Yr.
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    Popular Searches in Frederick, MD

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    Most Searched ZIP Codes in Frederick, MD

    • 21703
    • 21704

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