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Frederick, MD Retail Properties & Spaces for Lease

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55 results
Retail Space in Shell Condition
$20 SF/Yr

Retail Space in Shell Condition

358 W PATRICK Street, Frederick, MD 21701

2,279 SF retail or restaurant space for lease.

  • Prime restaurant or retail location in historic Downtown Frederick
  • 2,279 SF first floor space
  • Great visibility and walkability to downtown amenities
  • Free off‑street parking
  • Zoned DB Downtown Business
Updated: Jan 19
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Frederick Commercial Space with Drive-Through
$18 SF/Yr

Frederick Commercial Space with Drive-Through

198 THOMAS JOHNSON Drive, Frederick, MD 21701

Versatile commercial space in Frederick, ideal for various businesses.

  • High‑visibility location in Frederick City with heavy traffic flow.
  • Versatile +/- 1,890sf space suitable for various businesses.
  • Benefit from Drive‑through access (formerly a bank).
  • ADA accessibility with main‑level ramp.
  • Large parking lot.
Updated: Nov 9, 2025
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Frederick Commercial Space with Drive-Through
$18 SF/Yr

Frederick Commercial Space with Drive-Through

Versatile commercial space in Frederick, ideal for various businesses.

198 THOMAS JOHNSON Drive, Frederick, MD 21701
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Frederick Warehouse Retail Sublease Available
$8 SF/Yr

Frederick Warehouse Retail Sublease Available

4,800 SF warehouse retail sublease in Frederick, Maryland.

622 N MARKET Street, Frederick, MD 21701
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Downtown Frederick Retail Space Available
$63,685 SF/Yr

Downtown Frederick Retail Space Available

Street-level retail space in a prime downtown Frederick location.

244 E Patrick St, Frederick, MD 21701
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Turnkey Salon Space Available
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1,200 SF

Turnkey Salon Space Available

Salon space for lease at Clemson Corner, Frederick, Maryland.

7830 Wormans Mill Rd, Frederick, MD 21701
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Retail Space with Drive-Thru Potential
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4,790 SF

Retail Space with Drive-Thru Potential

4,790 SF retail space on 0.79 acres for lease.

1220 W Patrick St, Frederick, MD 20006
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Retail Space Near I-270
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Retail Space Near I-270

Retail space in fast-growing Frederick, Maryland near Westview Promenade.

4959-4969 Westview Drive, Frederick, MD 21703
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Urbana Pike Retail/Office Space
$3,875/Mo

Urbana Pike Retail/Office Space

Professional suites off 355 in Urbana, available in 2023.

3535 URBANA Pike, Frederick, MD 21704
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Retail Space Available For Rent
Contact for pricing
1,540 SF

Retail Space Available For Rent

Single tenant retail space available, approximately 1,540 square feet.

706 N East St, Frederick, MD 21701
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Landon Crossing Retail Opportunity
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36,123 SF

Landon Crossing Retail Opportunity

Ground lease and build-to-suit opportunities available at Landon Crossing.

3401 Urbana Pike, Frederick, MD 21704
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Downtown Frederick Retail Space Available
$3,010/Mo
2,094 SF

Downtown Frederick Retail Space Available

Retail space in downtown Frederick with onsite parking.

54 E Patrick St, Frederick, MD
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Retail Space in Growing Frederick
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4,700 SF

Retail Space in Growing Frederick

Retail space available in Frederick, Maryland's growing city.

403-419 S Jefferson St, Frederick, MD
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Upscale Shopping Center Space
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2,097 SF

Upscale Shopping Center Space

Retail space in affluent residential community near Rte. 270.

3501 John Simmons St, Frederick, MD
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Retail Space in Key Plaza
$22 SF/Yr
10,624 SF

Retail Space in Key Plaza

Mini-anchor space available in Key Plaza, Frederick, MD.

5600 Urbana Pike, Frederick, MD
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Frederick Retail Shopping Center Space
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21,262 SF

Frederick Retail Shopping Center Space

Retail space available in Frederick, Maryland shopping center.

5213-5227 Presidents Court, Frederick, MD
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Retail Space for Lease
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Retail Space for Lease

Retail property available for lease in Frederick, Maryland.

5316 New Design Road, Frederick, MD 21701
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Premier Lifestyle Center Retail Space
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2,024 SF

Premier Lifestyle Center Retail Space

Retail space available in Frederick County's premier lifestyle center.

5205-5253 Buckeystown Pike, Frederick, MD
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Flex Space in Biotech Hub
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21,200 SF

Flex Space in Biotech Hub

Flex/R&D space in Frederick County's premier biotech hub.

432 Mohican Dr, Frederick, MD
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Retail Space in Urbana Center
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5,546 SF

Retail Space in Urbana Center

Retail space available in high-volume, grocery-anchored shopping center.

3510 Sugarloaf Pkwy, Frederick, MD
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Flex/R&D Space in Biotech Hub
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2,900 SF

Flex/R&D Space in Biotech Hub

Flex/R&D space in Frederick's premier biotech hub.

8106 E Church St, Frederick, MD
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Flex Space in Biotech Hub
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5,500 SF

Flex Space in Biotech Hub

Flex/R&D space in Frederick's EastPark business community.

801 East Church St, Frederick, MD
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Urbana Pike Retail/Office Space
$5,935/Mo

Urbana Pike Retail/Office Space

Retail and office suites available for lease in Frederick, MD.

3535 URBANA Pike, Frederick, MD 21704
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Flex/R&D Space in Biotech Hub
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2,325 SF

Flex/R&D Space in Biotech Hub

Flex/R&D space in Frederick's dynamic EastPark business community.

Schifferstadt Blvd, Frederick, MD
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Frederick, MD Retail properties & Spaces Leasing Opportunities Market Analysis

Explore Retail properties & Spaces leasing options in Frederick, MD with 55 listings featured on our commercial real estate exchange. The current inventory includes 14,101,888,156 square feet of properties with an estimated lease value of $121 SF/Yr.

Estimated lease rates for Retail properties & Spaces in Frederick, MD begin at $2 SF/Yr, with an average of $17 SF/Yr and extend to $37 SF/Yr.
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