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Charleston, SC Mixed-use Properties for Sale

7 results
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Charleston Mixed-Use Investment Opportunity
$2,545,000
0.07 Acres

Charleston Mixed-Use Investment Opportunity

132 Spring St, Charleston, SC 29403

Flagship mixed-use property in downtown Charleston with commercial and residential units.

  • Prime downtown Charleston location in Elliotborough, ideal for hospitality and short‑term rentals.
  • Flagship mixed‑use property with commercial space (currently leased) and two renovated residential units.
  • Consistent revenue generation from short‑term rentals in both residential units.
  • Six possible off‑street parking spaces on Ashley Avenue.
  • Fully renovated in 2016 with high‑end finishes, original hardwood flooring, and high ceilings.
Updated: Dec 19, 2025
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Historic Mixed-Use Income Property
$4,399,000
0.07 Acres

Historic Mixed-Use Income Property

21 Broad St, Charleston, SC 29401

Renovated mixed-use building in downtown Charleston with income streams.

  • Income‑generating historic property grossing $242,000 annually with tenants in place.
  • Rare, grandfathered B&B license for the 2‑bedroom short‑term rental unit.
  • Fully renovated in 2018 (with additional improvements in 2023) with updated systems and finishes.
  • Prime downtown Charleston location within walking distance to key attractions.
  • Mixed‑use building with commercial office space and residential units offering versatile income streams.
Updated: Nov 20, 2025
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Charleston Mixed-Use Investment Opportunity
$6,000,000
8,317 SF

Charleston Mixed-Use Investment Opportunity

Prime Location, Modern Building, High ROI Potential

83 Mary St, Charleston, SC 29403
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King Street Loft - Live/Work Space
$675,000
840 SF

King Street Loft - Live/Work Space

Charleston Live/Work Loft, $675,000

487 King St, Charleston, SC 29403
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Rutledge Avenue Mixed-Use Building
$2,975,000
4,167 SF

Rutledge Avenue Mixed-Use Building

Mixed-use property with retail and residential units in Charleston.

107 Rutledge Ave, Charleston, SC 29401
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Mixed-Use Development in Charleston Gateway
Contact for pricing
4 SF

Mixed-Use Development in Charleston Gateway

Mixed-use development with apartments and retail in Charleston's Medical District.

102 President St, Charleston, SC 29403
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Charleston Mixed-Use Investment Opportunity
$8,490,000
12,000 SF

Charleston Mixed-Use Investment Opportunity

Mixed-use property with retail and residential units in downtown Charleston.

119 Spring St, Charleston, SC 29403
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Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 7 Active listings in Charleston, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 24 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Corner Properties on Cosgrove Avenue
$550,000
2 SF

Corner Properties on Cosgrove Avenue

High-traffic corner properties near Rivers Avenue with redevelopment potential.

2122 Cosgrove Ave North Charleston, North Charleston, SC 29405
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North Charleston Office Building
$1,200,000
6,674 SF

North Charleston Office Building

Prime location, high occupancy, great potential.

1495 Remount Rd, North Charleston, SC 29406
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Summerville Mixed-Use Development
$1,525,000
3,400 SF

Summerville Mixed-Use Development

Prime Summerville location, 25 units, ready to build.

2215 Central Ave, Summerville, SC 29483
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Summerville Mixed-Use Land
Contact for pricing
0.25 Acres

Summerville Mixed-Use Land

Three development options available. Fully permitted.

2215 Central Ave, Summerville, SC 29483
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Explore Off-Market Properties in Charleston, SC

Consider similar Off-Market properties in Charleston, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

387 Sumter St

387 Sumter St

Churches & religious facilities • 3,829 SF
Value Estimation by Request
387 Sumter St, Charleston, SC 29403
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1412 Savannah Hwy

1412 Savannah Hwy

Individual retail properties
Value Estimation by Request
1412 Savannah Hwy, Charleston, SC 29407
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184 Bay St

184 Bay St

Office space • 1,606 SF
Value Estimation by Request
184 Bay St, Charleston, SC 29401
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1176 Folly Rd

1176 Folly Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,951 SF
Value Estimation by Request
1176 Folly Rd, Charleston, SC 29412-4114
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2029 Ashley Riv Rd

2029 Ashley Riv Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,176 SF
Value Estimation by Request
2029 Ashley Riv Rd, Charleston, SC 29407-4714
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1930 Summerville Ave

1930 Summerville Ave

OFFICE/RESIDENTIAL (MIXED USE) • 1,040 SF
Value Estimation by Request
1930 Summerville Ave, Charleston, SC 29405-9373
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2 Simons St

2 Simons St

OFFICE/RESIDENTIAL (MIXED USE) • 1,949 SF
Value Estimation by Request
2 Simons St, Charleston, SC 29403-3716
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1136 Old Towne Rd

1136 Old Towne Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,452 SF
Value Estimation
$355,000
1136 Old Towne Rd, Charleston, SC 29407-6063
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2441 Ashley Riv Rd

2441 Ashley Riv Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,741 SF
Value Estimation by Request
2441 Ashley Riv Rd, Charleston, SC 29414-4601
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2464 Savannah Hwy

2464 Savannah Hwy

OFFICE/RESIDENTIAL (MIXED USE) • 1,508 SF
Value Estimation by Request
2464 Savannah Hwy, Charleston, SC 29414-5324
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830 Savage Rd

830 Savage Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,524 SF
Value Estimation by Request
830 Savage Rd, Charleston, SC 29414-5651
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1565 Folly Rd

1565 Folly Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,073 SF
Value Estimation by Request
1565 Folly Rd, Charleston, SC 29412-9563
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1993 Ashley Riv Rd

1993 Ashley Riv Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,884 SF
Value Estimation by Request
1993 Ashley Riv Rd, Charleston, SC 29407-4736
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2013 Herbert St

2013 Herbert St

OFFICE/RESIDENTIAL (MIXED USE) • 1,630 SF
Value Estimation by Request
2013 Herbert St, Charleston, SC 29405-9363
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905 Hbr Vw Rd

905 Hbr Vw Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,347 SF
Value Estimation by Request
905 Hbr Vw Rd, Charleston, SC 29412-4910
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502 Meeting St

502 Meeting St

OFFICE/RESIDENTIAL (MIXED USE) • 2,664 SF
Value Estimation by Request
502 Meeting St, Charleston, SC 29403-5071
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219 Rutledge Ave

219 Rutledge Ave

OFFICE/RESIDENTIAL (MIXED USE) • 3,889 SF
Value Estimation by Request
219 Rutledge Ave, Charleston, SC 29403-5791
View details

Charleston, SC Mixed-Use Properties Investment Opportunities Market Analysis

Explore 30 mixed-use properties for sale in Charleston, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 625,826 square feet of properties for sale, with an estimated market value of $38,594,000.

Prices for multi use buildings in Charleston, SC start at $65,000, averaging $3,508,545, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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