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    Poughkeepsie, NY Mixed-use Properties for Sale

    13 results
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    Restored Mixed-Use Poughkeepsie Rowhouse
    $875,000
    1,900 SF

    Restored Mixed-Use Poughkeepsie Rowhouse

    328 Main St, Poughkeepsie, NY 12601

    Restored mixed-use building with commercial space and apartments in Poughkeepsie.

    • Restored 4‑story mixed‑use building in Downtown Poughkeepsie.
    • Features a 1,900SF occupied ground‑floor commercial space.
    • Includes three occupied apartments with annual inspections and updates.
    • Rebuilt in 2010/2011 with modern amenities like central heating/AC and video security.
    • Restored hardwood floors and original exterior facade.
    Updated: Jan 24
    View details
    Mixed-Use Building in Downtown Poughkeepsie
    $1,290,000
    0.08 Acres

    Mixed-Use Building in Downtown Poughkeepsie

    302-304 Main St, Poughkeepsie, NY 12601

    Mixed-use building with commercial and residential units in prime location.

    • Prime location in the heart of Poughkeepsie's Downtown Business District, near the Civic Center, Hotel, Bardavon, restaurants, and bars.
    • Mixed‑use building with 5 levels of rental space, offering a diverse mix of commercial and residential units.
    • Existing commercial unit suitable for a bar/cafe/restaurant, spanning 5,000 sq. ft. across two levels.
    • Includes three residential units: a studio, a 1‑bedroom apartment, and a 3‑bedroom apartment, all currently occupied.
    • Rear exit provides access to shared public parking.
    Updated: Dec 19, 2025
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    Restored Mixed-Use Poughkeepsie Rowhouse
    $875,000
    1,900 SF

    Restored Mixed-Use Poughkeepsie Rowhouse

    Restored mixed-use building with storefront and apartments in downtown Poughkeepsie.

    330 Main St, Poughkeepsie, NY 12601
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    Mixed-Use Rowhouses in Downtown Poughkeepsie
    $1,450,000
    0.12 Acres

    Mixed-Use Rowhouses in Downtown Poughkeepsie

    Twin mixed-use buildings with commercial space and apartments in Poughkeepsie.

    328-330 Main St, Poughkeepsie, NY 12601
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    Mixed-Use Property in Downtown Poughkeepsie
    Pending
    $375,000
    5,181 SF

    Mixed-Use Property in Downtown Poughkeepsie

    Mixed-use property with office, apartment, and warehouse spaces in Poughkeepsie.

    218 Main St, Poughkeepsie, NY 12601
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    Historic Trolley Barn Mixed-Use Property
    $1,250,000
    16,926 SF

    Historic Trolley Barn Mixed-Use Property

    Partially renovated mixed-use property in historic Poughkeepsie Trolley Barn.

    489 Main St, Poughkeepsie, NY 12601
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    Poughkeepsie Redevelopment Opportunity
    $2,900,000
    0.11 Acres

    Poughkeepsie Redevelopment Opportunity

    Mixed-use redevelopment opportunity in Poughkeepsie's growing Innovation District.

    194 Church St, Poughkeepsie, NY 12601
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    Mixed-Use Building in Opportunity Zone
    $699,900

    Mixed-Use Building in Opportunity Zone

    Mixed-use building with retail, office, and residential spaces.

    39 Market St, Poughkeepsie, NY 12601
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    Mixed-Use Property with Parking
    $375,000

    Mixed-Use Property with Parking

    Mixed-use property with off-street parking in historic district.

    59 Montgomery St, Poughkeepsie, NY 12601
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    Mixed-Use Property with Apartments
    $689,000

    Mixed-Use Property with Apartments

    Mixed-use property featuring a store and two apartments.

    2748 W Main St, Poughkeepsie, NY 12590
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    Mixed-Use Investment Opportunity Near Vassar
    $950,000

    Mixed-Use Investment Opportunity Near Vassar

    Turnkey 5-unit mixed-use building with parking near Vassar Brothers.

    48 Columbia St, Poughkeepsie, NY 12601
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    Poughkeepsie Flex Space Investment
    $1,075,000
    8,170 SF

    Poughkeepsie Flex Space Investment

    8,170 SF Flex Space, Redevelopment Potential

    4 Buckingham Ave, Poughkeepsie, NY 12601
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    Poughkeepsie CBD Development Opportunity
    $1,750,000
    0.97 Acres

    Poughkeepsie CBD Development Opportunity

    Mixed-use property, high potential, in-place income.

    355 Mill St, Poughkeepsie, NY 12601
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    Based on your search, we've compiled 468 Potential Opportunities for your consideration. Besides 13 Active listings in Poughkeepsie, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 450 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Highland Riverfront Development Opportunity
    $24,500,000

    Highland Riverfront Development Opportunity

    Prime Hudson River location, massive development potential.

    200 Blue Point Rd, Highland, NY 12528
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    Highland Mixed-Use Investment Opportunity
    $950,000

    Highland Mixed-Use Investment Opportunity

    Prime Highland location, high potential, $950,000.

    10 Roberts Rd, Highland, NY 12528
    View details
    Mixed-Use Property with Development Potential
    $725,000

    Mixed-Use Property with Development Potential

    4.63-acre mixed-use property with road frontage and development opportunities.

    1380 Route 44, Pleasant Valley, NY 12569
    View details
    Versatile Mixed-Use Property For Sale
    $929,000

    Versatile Mixed-Use Property For Sale

    Two-for-one property with retail/warehouse and residential home.

    1-7 West Rd, Pleasant Valley, NY 12569
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Poughkeepsie Redevelopment Opportunity
    $2,900,000
    0.11 Acres

    Poughkeepsie Redevelopment Opportunity

    Mixed-use redevelopment opportunity in Poughkeepsie's growing Innovation District.

    194 Church St, Poughkeepsie, NY 12601
    View details

    Explore Off-Market Properties in Poughkeepsie, NY

    Consider similar Off-Market properties in Poughkeepsie, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    8 Cherry St

    8 Cherry St

    OFFICE/RESIDENTIAL (MIXED USE) • 25,272 SF
    Value Estimation
    $2,175,000
    8 Cherry St, Poughkeepsie, NY 12601-3494
    View details
    25 Husky Hl Rd

    25 Husky Hl Rd

    STORE/OFFICE (MIXED USE) • 1,529 SF
    Value Estimation by Request
    25 Husky Hl Rd, Poughkeepsie, NY 12601-5583
    View details
    800 Main St

    800 Main St

    STORE/OFFICE (MIXED USE) • 17,303 SF
    Value Estimation
    $1,645,000
    800 Main St, Poughkeepsie, NY 12603-1846
    View details
    28 Pershing Ave

    28 Pershing Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 2,090 SF
    Value Estimation by Request
    28 Pershing Ave, Poughkeepsie, NY 12601-2730
    View details
    43 Raymond Ave, Unit 53

    43 Raymond Ave, Unit 53

    STORE/OFFICE (MIXED USE) • 7,980 SF
    Value Estimation
    $1,195,000
    43 Raymond Ave, Poughkeepsie, NY 12603-2317
    View details
    70 Lent St

    70 Lent St

    Mixed-use properties
    Value Estimation by Request
    70 Lent St, Poughkeepsie, NY 12601
    View details
    297 Ml St

    297 Ml St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,080 SF
    Value Estimation by Request
    297 Ml St, Poughkeepsie, NY 12601-3113
    View details
    399 Main St

    399 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 9,600 SF
    Value Estimation
    $580,000
    399 Main St, Poughkeepsie, NY 12601-3331
    View details
    300 Main St

    300 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,655 SF
    Value Estimation by Request
    300 Main St, Poughkeepsie, NY 12601-3110
    View details
    458-460 Main St

    458-460 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 9,246 SF
    Value Estimation
    $630,000
    458-460 Main St, Poughkeepsie, NY 12601
    View details
    35 Main St

    35 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 20,920 SF
    Value Estimation
    $3,340,000
    35 Main St, Poughkeepsie, NY 12601-2935
    View details

    Poughkeepsie, NY Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 463 mixed-use properties for sale in Poughkeepsie, NY, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 8,652,312 square feet of properties for sale, with an estimated market value of $144,525,000.

    Sale prices for multi use buildings in Poughkeepsie, NY start at $50,000, averaging $385,400, and reaching up to $4,395,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Mixed-use properties for Sale Near Poughkeepsie, NY

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    Most Searched ZIP Codes in Poughkeepsie, NY

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    • 12603

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