Poughkeepsie, NY Mixed-use properties for sale

Mixed-Use Building in Downtown Poughkeepsie

$1,290,000

0.08 Acres

Mixed-Use Building in Downtown Poughkeepsie

302-304 Main St, Poughkeepsie, NY 12601

Mixed-use building with commercial and residential units in prime location.

Prime location in the heart of Poughkeepsie's Downtown Business District, near the Civic Center, Hotel, Bardavon, restaurants, and bars.
Mixed‑use building with 5 levels of rental space, offering a diverse mix of commercial and residential units.
Existing commercial unit suitable for a bar/cafe/restaurant, spanning 5,000 sq. ft. across two levels.
Includes three residential units: a studio, a 1‑bedroom apartment, and a 3‑bedroom apartment, all currently occupied.
Rear exit provides access to shared public parking.

Updated: Dec 19, 2025

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Mixed-Use Rowhouses in Downtown Poughkeepsie

$1,450,000

0.12 Acres

Mixed-Use Rowhouses in Downtown Poughkeepsie

328-330 Main St, Poughkeepsie, NY 12601

Twin mixed-use buildings with commercial space and apartments in Poughkeepsie.

Twin, fully renovated 4‑story mixed‑use buildings in Downtown Poughkeepsie
Each building features a 1,900SF ground‑floor commercial space with basement access and three apartments
Modern amenities include central heating/AC, video security system, and kitchen appliances
Exterior facade restored to its original 1925 look, with interior hardwood floors
Each unit is inspected annually and updated as needed

Updated: Jan 3

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Mixed-Use Property in Downtown Poughkeepsie

Pending

$375,000

5,181 SF

Mixed-Use Property in Downtown Poughkeepsie

Mixed-use property with office, apartment, and warehouse spaces in Poughkeepsie.

218 Main St, Poughkeepsie, NY 12601

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Historic Trolley Barn Mixed-Use Property

$1,250,000

16,926 SF

Historic Trolley Barn Mixed-Use Property

Partially renovated mixed-use property in historic Poughkeepsie Trolley Barn.

489 Main St, Poughkeepsie, NY 12601

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$950,000

Mixed-Use Investment Opportunity Near Vassar

Turnkey 5-unit mixed-use building with parking near Vassar Brothers.

48 Columbia St, Poughkeepsie, NY 12601

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$1,075,000

8,170 SF

Poughkeepsie Flex Space Investment

8,170 SF Flex Space, Redevelopment Potential

4 Buckingham Ave, Poughkeepsie, NY 12601

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$689,000

Mixed-Use Property with Apartments

Mixed-use property featuring a store and two apartments.

2748 W Main St, Poughkeepsie, NY 12590

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$699,900

Mixed-Use Building in Opportunity Zone

Mixed-use building with retail, office, and residential spaces.

39 Market St, Poughkeepsie, NY 12601

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$375,000

Mixed-Use Property with Parking

Mixed-use property with off-street parking in historic district.

59 Montgomery St, Poughkeepsie, NY 12601

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Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

$950,000

Highland Mixed-Use Investment Opportunity

Prime Highland location, high potential, $950,000.

10 Roberts Rd, Highland, NY 12528

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$2,100,000

70.00 Acres

Highland 70-Acre Multi-Use Property

70 acres, 4 buildings, prime location.

243 Vineyard Ave, Highland, NY 12528

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$725,000

Mixed-Use Property with Development Potential

4.63-acre mixed-use property with road frontage and development opportunities.

1380 Route 44, Pleasant Valley, NY 12569

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$929,000

Versatile Mixed-Use Property For Sale

Two-for-one property with retail/warehouse and residential home.

1-7 West Rd, Pleasant Valley, NY 12569

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$2,900,000

0.11 Acres

Poughkeepsie Redevelopment Opportunity

Mixed-use redevelopment opportunity in Poughkeepsie's growing Innovation District.

194 Church St, Poughkeepsie, NY 12601

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Explore Off-Market Properties in Poughkeepsie, NY

Consider similar Off-Market properties in Poughkeepsie, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

70 Lent St

Mixed-use properties

Value Estimation by Request

70 Lent St, Poughkeepsie, NY 12601

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931 Dutchess Tpke

Individual retail properties • 1,948 SF

Value Estimation by Request

931 Dutchess Tpke, Arlington, NY 12603

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OFFICE/RESIDENTIAL (MIXED USE) • 164,097 SF

Value Estimation by Request

332 Main St, Poughkeepsie, NY 12601-3110

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1 Gate Dr

STORE/OFFICE (MIXED USE) • 2,956 SF

Value Estimation

$390,000

1 Gate Dr, Poughkeepsie, NY 12601-5621

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341 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 27,580 SF

Value Estimation by Request

341 Main St, Poughkeepsie, NY 12601-3116

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Poughkeepsie, NY Mixed-Use Properties Investment Opportunities Market Analysis

Explore 459 mixed-use properties for sale in Poughkeepsie, NY, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 8,645,342 square feet of properties for sale, with an estimated market value of $142,775,000.

Prices for multi use buildings in Poughkeepsie, NY start at $50,000, averaging $382,774, and reaching up to $4,395,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

Poughkeepsie, NY Mixed-use Properties for Sale

Mixed-Use Building in Downtown Poughkeepsie

Mixed-use building with commercial and residential units in prime location.

Mixed-Use Rowhouses in Downtown Poughkeepsie

Twin mixed-use buildings with commercial space and apartments in Poughkeepsie.