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Palmdale, CA Mixed-use Properties for Sale

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Palmdale Mixed-Use Building For Sale
$400,000
1,599 SF

Palmdale Mixed-Use Building For Sale

38525 E 6Th St, Palmdale, CA 93550

Freestanding commercial building with yard and excellent visibility in Palmdale.

  • Freestanding commercial building on a large lot.
  • Excellent street visibility.
  • Secure yard.
  • Front and rear access.
  • Alleyway access.
Updated: Dec 12, 2025
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Challenger Business Park: Palmdale Investment
$9,200,000
25,306 SF

Challenger Business Park: Palmdale Investment

450 Palmdale Blvd, Palmdale, CA 93551

Mixed-use medical & retail investment. High NOI.

  • Excellent proximity to Palmdale Regional Hospital.
  • Convenient freeway access.
Updated: Dec 11, 2024
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450 Palmdale Blvd, Palmdale, CA 93551
$9,200,000
2.20 Acres

450 Palmdale Blvd, Palmdale, CA 93551

Mixed-use properties • 2.20 Acres

450 Palmdale Blvd, Palmdale, CA 93551
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Newcomb's Ranch: Iconic Mountain Retreat
$5,985,000
10.17 Acres

Newcomb's Ranch: Iconic Mountain Retreat

10-Acre Mountain Property, Huge Potential

CA-2 Mile Marker Ln 50.93, Palmdale, CA 91011
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Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 4 Active listings in Palmdale, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 26 Off-Market properties to explore as potential leads, plus 3 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Commercial Industrial Property on Highway
$1,600,000

Commercial Industrial Property on Highway

13,200 sq ft commercial industrial property with highway frontage.

42213 Sierra Hwy, Lancaster, CA 93535
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Lancaster Mixed-Use Zoned Property
$600,000

Lancaster Mixed-Use Zoned Property

Mixed-use property with commercial and retail potential in Lancaster, CA.

Sierra Hwy Hwy, Lancaster, CA 93535
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Pasadena Mixed-Use Investment Opportunity
$1,800,000
4,068 SF

Pasadena Mixed-Use Investment Opportunity

Prime Pasadena location, three buildings, high potential.

1736 Sierra Bonita Ave, Pasadena, CA 91104
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Prime Pasadena Mixed-Use Trio
$5,500,000
1,980 SF

Prime Pasadena Mixed-Use Trio

Three buildings, huge potential, Rose Bowl proximity.

451 Del Monte St, Pasadena, CA 91103
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Palmdale Land For Sale
$899,900

Palmdale Land For Sale

6.08 acre lot in West Palmdale, zoned for mixed-use.

Vic Av Avenue S, Palmdale, CA 93550
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Palmdale Commercial Development Opportunity
$90,000

Palmdale Commercial Development Opportunity

7,251 sq ft lot ready for development in Palmdale.

88 Vac Palmdale Blvd, Palmdale, CA 93552
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Palmdale Land For Sale
$899,900
264,819.00 Acres

Palmdale Land For Sale

6.08 acre lot in West Palmdale, zoned residential.

1 Vac/Avenue Ave S/Vic, Palmdale, CA 93551
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Explore Off-Market Properties in Palmdale, CA

Consider similar Off-Market properties in Palmdale, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

8701 Palmdale Blvd

8701 Palmdale Blvd

OFFICE/RESIDENTIAL (MIXED USE) • 3,050 SF
Value Estimation by Request
8701 Palmdale Blvd, Palmdale, CA 93552-2903
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853 Auto Ctr Dr

853 Auto Ctr Dr

STORE/OFFICE (MIXED USE) • 9,680 SF
Value Estimation
$2,465,000
853 Auto Ctr Dr, Palmdale, CA 93551-4492
View details
39553 Sierra Hwy

39553 Sierra Hwy

STORE/OFFICE (MIXED USE) • 6,950 SF
Value Estimation
$1,630,000
39553 Sierra Hwy, Palmdale, CA 93550-3300
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1854 Palmdale Blvd

1854 Palmdale Blvd

STORE/OFFICE (MIXED USE) • 7,132 SF
Value Estimation
$960,000
1854 Palmdale Blvd, Palmdale, CA 93550-4852
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42164 40th E St

42164 40th E St

OFFICE/RESIDENTIAL (MIXED USE) • 3,874 SF
Value Estimation
$2,960,000
42164 40th E St, Palmdale, CA 93552
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38000 Sierra Hwy

38000 Sierra Hwy

STORE/OFFICE (MIXED USE) • 1,306 SF
Value Estimation
$815,000
38000 Sierra Hwy, Palmdale, CA 93550-4605
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4621 Ave S Ave

4621 Ave S Ave

STORE/OFFICE (MIXED USE) • 48,894 SF
Value Estimation
$6,585,000
4621 Ave S Ave, Palmdale, CA 93552-4484
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CA-2 Mile Marker Ln 50.93

CA-2 Mile Marker Ln 50.93

Restaurants • 10,026 SF
Value Estimation by Request
CA-2 Mile Marker Ln 50.93, Palmdale, CA 91011
View details
2045 Palmdale Blvd

2045 Palmdale Blvd

STORE/OFFICE (MIXED USE) • 9,480 SF
Value Estimation
$1,725,000
2045 Palmdale Blvd, Palmdale, CA 93550-4036
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38125 6th E St

38125 6th E St

STORE/OFFICE (MIXED USE) • 2,574 SF
Value Estimation by Request
38125 6th E St, Palmdale, CA 93550-4632
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927 Palmdale Blvd

927 Palmdale Blvd

OFFICE/RESIDENTIAL (MIXED USE) • 1,527 SF
Value Estimation by Request
927 Palmdale Blvd, Palmdale, CA 93550-4711
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826 Blvd

826 Blvd

Mixed-use properties • 2,000 SF
Value Estimation by Request
826 Blvd, Palmdale, CA 93550
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818 Ave Q6

818 Ave Q6

OFFICE/RESIDENTIAL (MIXED USE) • 1,575 SF
Value Estimation by Request
818 Ave Q6, Palmdale, CA 93550-4716
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38434 9th E St

38434 9th E St

OFFICE/RESIDENTIAL (MIXED USE) • 7,499 SF
Value Estimation
$965,000
38434 9th E St, Palmdale, CA 93550-4707
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35656 Sierra Hwy

35656 Sierra Hwy

STORE/OFFICE (MIXED USE) • 640 SF
Value Estimation by Request
35656 Sierra Hwy, Palmdale, CA 93550-9335
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40005 10th W St

40005 10th W St

STORE/OFFICE (MIXED USE) • 27,564 SF
Value Estimation
$5,950,000
40005 10th W St, Palmdale, CA 93551-3037
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5645 Ave T T

5645 Ave T T

OFFICE/RESIDENTIAL (MIXED USE) • 1,150 SF
Value Estimation by Request
5645 Ave T T, Palmdale, CA 93552-6002
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40106 12th W St

40106 12th W St

OFFICE/RESIDENTIAL (MIXED USE) • 3,173 SF
Value Estimation
$845,000
40106 12th W St, Palmdale, CA 93551-3025
View details
957 Ave Q9

957 Ave Q9

OFFICE/RESIDENTIAL (MIXED USE) • 820 SF
Value Estimation by Request
957 Ave Q9, Palmdale, CA 93550-4734
View details
935 Palmdale Blvd

935 Palmdale Blvd

OFFICE/RESIDENTIAL (MIXED USE) • 1,533 SF
Value Estimation by Request
935 Palmdale Blvd, Palmdale, CA 93550
View details

Palmdale, CA Mixed-Use Properties Investment Opportunities Market Analysis

Explore 30 mixed-use properties for sale in Palmdale, CA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 2,893,631 square feet of properties for sale, with an estimated market value of $33,925,000.

Sale prices for multi use buildings in Palmdale, CA start at $240,000, averaging $1,696,250, and reaching up to $9,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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