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    Middlesex County, MA Mixed-use Properties for Lease

    12 results
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    Landmark Building in Downtown Natick
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    Landmark Building in Downtown Natick

    2 Summer St, Natick, MA 01760

    Prime retail and office spaces in a signature building.

    • Prime location in the heart of Downtown Natick at the intersection of Main Street (Route 27) and West Central Street (Route 135).
    • High visibility and accessibility, steps from Natick Common.
    • Character‑rich spaces within a signature landmark building.
    • Suitable for various uses: Retail, Office, Education, Showroom, and more.
    • Located in the center of local dining, shopping, and entertainment options.
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    Mixed-Use Building in Melrose
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    Mixed-Use Building in Melrose

    681-697 Main St, Melrose, MA 02176

    New construction mixed-use building with retail and commercial space.

    • Prime Main Street location in Melrose.
    • New construction, mixed‑use building.
    • Flexible commercial space layouts to fit tenant needs.
    • 42 free municipal parking spots adjacent to the property.
    • Full height basements included with Main St retail spaces.
    Updated: Sep 23, 2025
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    Watertown Flex/Office Space Available
    $25 SF/Yr
    3,700 SF

    Watertown Flex/Office Space Available

    Versatile flex/office space in a vibrant, growing Watertown neighborhood.

    385 Pleasant St, Watertown, MA 02472
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    Unique Loft in Davis Square
    $9,750 / Mo

    Unique Loft in Davis Square

    Rare live/work loft with commercial kitchen and private yard.

    70 Howard St, Somerville, MA 02144
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    Loft Office Suites For Rent
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    530 SF

    Loft Office Suites For Rent

    Shared office suites with common kitchenette in mixed-use building.

    1121 Washington St, Newton, MA 02465
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    New Retail Space in Everett
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    2,917 SF

    New Retail Space in Everett

    New mixed-use development with retail space for lease.

    202 Mill Rd, Everett, MA
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    Downtown Marlborough Mixed-Use Development
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    Downtown Marlborough Mixed-Use Development

    Mixed-use property with retail space in a high-traffic downtown location.

    57 Main St, Marlborough, MA 01752
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    Vibrant Mixed-Use Neighborhood Retail Space
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    2,406 SF

    Vibrant Mixed-Use Neighborhood Retail Space

    Retail space in a popular mixed-use destination.

    88 Arsenal Yards Blvd, Watertown, MA
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    Retail/Restaurant Space in Chestnut Hill
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    5,140 SF

    Retail/Restaurant Space in Chestnut Hill

    New mixed-use building with retail space for lease.

    1180 Boylston St, Brookline, MA 02445
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    Live-Work-Play Community Retail Space
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    7,047 SF

    Live-Work-Play Community Retail Space

    Mixed-use community with retail and luxury residential units for rent.

    525 Common St, Belmont, MA 02478
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    Victorian Style Office Suite
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    Victorian Style Office Suite

    First floor office suite in mixed-use commercial building.

    629 Main St, Woburn, MA 01801
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    Retail Space in Mixed-Use Development
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    2,446 SF

    Retail Space in Mixed-Use Development

    New retail space in a dynamic mixed-use development.

    35 Garvey St, Everett, MA 02149
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    Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 12 Active listings in Middlesex County, MA, we suggest exploring alternatives. Similar 39 Properties for Sales.

    Explore Similar Spaces for Sale in Middlesex County, MA

    Consider Similar Space for Sale. We found 12 Spaces in Nearby Locations matching your search parameters.

    Lowell Mixed-Use Investment Opportunity
    $795,000
    3,774 SF

    Lowell Mixed-Use Investment Opportunity

    Mixed-use property with commercial space and residential unit in Lowell.

    525 Chelmsford St, Lowell, MA 01851
    View details
    Somerville Mixed-Use Building For Sale
    $1,749,000
    3,115 SF

    Somerville Mixed-Use Building For Sale

    Mixed-use building with income potential or condo conversion opportunity.

    148 Pearl St, Somerville, MA 02145
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    Mixed-Use Building Near UMASS Lowell
    $1,300,000
    7,178 SF

    Mixed-Use Building Near UMASS Lowell

    Five-unit mixed-use building with retail space and residential units.

    169-171 Salem St, Lowell, MA 01854
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    Victorian Mixed-Use Building in Melrose
    $1,450,000
    4,497 SF

    Victorian Mixed-Use Building in Melrose

    Mixed-use property with residential and commercial units in downtown Melrose.

    3-5 E Foster St, Melrose, MA 02176
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    Maplewood Square Investment Opportunity
    $1,599,900
    7,000 SF

    Maplewood Square Investment Opportunity

    Four-unit commercial building and two-family home in prime location.

    697-705 Salem St, Malden, MA 02148
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    Renovated Mixed-Use Building Near I-495
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    Renovated Mixed-Use Building Near I-495

    Two-story renovated building with medical office and luxury apartment.

    205 Chelmsford St, Chelmsford, MA 01824
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    Wakefield Mixed-Use Value-Add Opportunity
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    Wakefield Mixed-Use Value-Add Opportunity

    Mixed-use property in Wakefield center with value-add potential.

    401-411 Main St, Wakefield, MA 01880
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    Value-Add Real Estate Assemblage Opportunity
    Contact for pricing
    20,970 SF

    Value-Add Real Estate Assemblage Opportunity

    Multi-parcel assemblage in Everett, MA, with redevelopment potential.

    1911-1919 Revere Beach Pkwy, Everett, MA 02149
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    Melrose Mixed-Use Investment Opportunity
    Contact for pricing
    4,448 SF

    Melrose Mixed-Use Investment Opportunity

    4,448 SF building in Melrose Market with BA-2 zoning.

    437-445 Franklin St, Melrose, MA 02176
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    Multifamily with Commercial Space
    $1,995,000

    Multifamily with Commercial Space

    Multi-family property with commercial space and licensed rooming house.

    55-57 Crescent St, Waltham, MA 02453
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    Downtown Natick Retail Opportunity
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    Downtown Natick Retail Opportunity

    Retail space in a newly developed mixed-use building.

    21 Summer St, Natick, MA 01760
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    Versatile Arlington Commercial Property
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    Versatile Arlington Commercial Property

    Mixed-use property with residential, commercial, and industrial components.

    52-56 Dudley Street Pl, Arlington, MA 02476
    View details

    Middlesex County, MA Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Middlesex County, MA with 12 listings featured on our commercial real estate exchange. The current inventory includes 161,172,000 square feet of properties with an estimated lease value of $25 SF/Yr.

    Estimated lease rates for Mixed-use properties in Middlesex County, MA begin at $25 SF/Yr, with an average of $25 SF/Yr and extend to $25 SF/Yr.
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    Mixed-use properties by market

    Browse Mixed-use properties for Lease Near Middlesex, MA

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