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    South Dakota Medical Space for Sale

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    Versatile Commercial Building on Sioux Avenue
    Contact for pricing
    2,085 SF

    Versatile Commercial Building on Sioux Avenue

    604 E Sioux Ave, Pierre, SD 57501

    Adaptable commercial property with high visibility and drive-through canopy.

    • Excellent frontage at the signalized intersection of Sioux Avenue and Ree Street
    • 13,980 average vehicles per day
    • Drive through canopy
    • 10 parking spots
    • Possible use could serve medical, office or retail opportunities
    View details
    Based on your search, we've compiled 204 Potential Opportunities for your consideration. Besides 1 Active listings in South Dakota, we suggest exploring several alternatives: similar 203 Off-Market properties to explore as potential leads

    Explore Off-Market Properties in South Dakota

    Consider similar Off-Market properties in South Dakota. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    5422 Arrowhead Pkwy

    5422 Arrowhead Pkwy

    Restaurants • 20,026 SF
    Value Estimation by Request
    5422 Arrowhead Pkwy, Sioux Falls, SD 57110
    View details
    5418 Arrowhead Pkwy

    5418 Arrowhead Pkwy

    Individual retail properties • 2,055 SF
    Value Estimation by Request
    5418 Arrowhead Pkwy, Sioux Falls, SD 57110
    View details
    520 22nd St

    520 22nd St

    MEDICAL BUILDING • 4,981 SF
    Value Estimation by Request
    520 22nd St, Sioux Falls, SD 57105-1702
    View details
    3401 Kelley Ave

    3401 Kelley Ave

    MEDICAL BUILDING • 4,376 SF
    Value Estimation by Request
    3401 Kelley Ave, Sioux Falls, SD 57106-6300
    View details
    108 4th St

    108 4th St

    DENTAL BUILDING • 5,670 SF
    Value Estimation by Request
    108 4th St, Dell Rapids, SD 57022-1508
    View details
    510 24th St

    510 24th St

    MEDICAL BUILDING • 1,350 SF
    Value Estimation by Request
    510 24th St, Sioux Falls, SD 57105-1700
    View details
    4601 Homefield Dr

    4601 Homefield Dr

    DENTAL BUILDING • 13,064 SF
    Value Estimation
    $640,000
    4601 Homefield Dr, Sioux Falls, SD 57106-3506
    View details
    1205 Grange Ave

    1205 Grange Ave

    MEDICAL BUILDING • 87,762 SF
    Value Estimation
    $3,610,000
    1205 Grange Ave, Sioux Falls, SD 57105-0407
    View details
    1310 22nd St

    1310 22nd St

    MEDICAL BUILDING • 51,004 SF
    Value Estimation
    $2,120,000
    1310 22nd St, Sioux Falls, SD 57105-1501
    View details
    1105 Holly Blvd

    1105 Holly Blvd

    MEDICAL BUILDING • 6,672 SF
    Value Estimation by Request
    1105 Holly Blvd, Brandon, SD 57005-1426
    View details
    1700 Southeastern Ave

    1700 Southeastern Ave

    DENTAL BUILDING • 12,664 SF
    Value Estimation
    $610,000
    1700 Southeastern Ave, Sioux Falls, SD 57103-3227
    View details
    613 41st St

    613 41st St

    DENTAL BUILDING • 4,937 SF
    Value Estimation by Request
    613 41st St, Sioux Falls, SD 57105-6403
    View details
    801 Minnesota Ave

    801 Minnesota Ave

    MEDICAL BUILDING • 2,088 SF
    Value Estimation by Request
    801 Minnesota Ave, Sioux Falls, SD 57104-4828
    View details
    2910 26th St

    2910 26th St

    MEDICAL BUILDING • 8,599 SF
    Value Estimation by Request
    2910 26th St, Sioux Falls, SD 57103-4034
    View details
    1400 22nd St

    1400 22nd St

    MEDICAL BUILDING • 85,407 SF
    Value Estimation
    $5,290,000
    1400 22nd St, Sioux Falls, SD 57105-1505
    View details
    2600 Western Ave

    2600 Western Ave

    DENTAL BUILDING • 2,948 SF
    Value Estimation by Request
    2600 Western Ave, Sioux Falls, SD 57105-4429
    View details
    117 Holly Blvd

    117 Holly Blvd

    MEDICAL BUILDING • 4,224 SF
    Value Estimation by Request
    117 Holly Blvd, Brandon, SD 57005-1131
    View details
    607 18th St

    607 18th St

    MEDICAL BUILDING • 7,560 SF
    Value Estimation by Request
    607 18th St, Sioux Falls, SD 57105
    View details
    2400 41st St

    2400 41st St

    DENTAL BUILDING • 6,770 SF
    Value Estimation by Request
    2400 41st St, Sioux Falls, SD 57105-6119
    View details
    3813 Kiwanis Cir, Unit 100

    3813 Kiwanis Cir, Unit 100

    MEDICAL BUILDING • 2,095 SF
    Value Estimation by Request
    3813 Kiwanis Cir, Sioux Falls, SD 57105-4266
    View details
    1737 Cleveland Ave

    1737 Cleveland Ave

    MEDICAL BUILDING • 6,284 SF
    Value Estimation by Request
    1737 Cleveland Ave, Sioux Falls, SD 57103-3245
    View details
    101 Cleveland Ave

    101 Cleveland Ave

    MEDICAL BUILDING • 3,913 SF
    Value Estimation by Request
    101 Cleveland Ave, Sioux Falls, SD 57103-2188
    View details
    1727 Cleveland Ave

    1727 Cleveland Ave

    MEDICAL BUILDING • 7,676 SF
    Value Estimation by Request
    1727 Cleveland Ave, Sioux Falls, SD 57103-3245
    View details

    South Dakota Medical Space Investment Opportunities Market Analysis

    Explore 204 medical space for sale in South Dakota on our real estate platform. These investment opportunities span a total of 2,828,642 square feet of properties for sale, with an estimated market value of $31,270,000.

    Sale prices for medical space in South Dakota start at $155,000, averaging $363,604, and reaching up to $2,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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