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    Comal County, TX Medical Office Space for Lease

    88 results
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    Serene Office Park Setting
    $16 SF/Yr
    3,275 SF

    Serene Office Park Setting

    14855 Blanco Road, San Antonio, TX 78216

    Office space in a well-located, highly visible office park.

    • Premier business environment in a serene office park setting.
    • Highly visible location at the Blanco and Bitters intersection.
    • Effortless access to 1604, 281, and Wurzbach Parkway.
    • Ample parking available.
    • Anchored by the well‑known Melting Pot Restaurant.
    Updated: Mar 25
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    Medical Office Space Near Hospital
    $24 SF/Yr
    7,000 SF

    Medical Office Space Near Hospital

    921 Lakeview Blvd, New Braunfels, TX 78130

    Second-generation medical office space available near Christus Hospital.

    • Prime location, just 2‑3 blocks from Christus Hospital and Christus Santa Rosa Hospital.
    • Functional medical office space with approximately 3,500 SF, featuring multiple exam rooms, waiting rooms, and office space.
    • Second‑generation medical space ready for immediate use.
    • Elevator access provides easy access to the 2nd‑floor suite.
    • Ample parking available.
    Updated: Nov 21, 2025
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    Generations Drive Professional Office Space
    $25 SF/Yr
    5,294 SF

    Generations Drive Professional Office Space

    Shell space available in medical office development near Resolute Health.

    790 Generations Drive, New Braunfels, TX 78130
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    New Braunfels Medical/Office Space
    $25 SF/Yr
    13,411 SF

    New Braunfels Medical/Office Space

    Move-in ready office space near hospitals and major routes.

    66 Gruene Park Dr, New Braunfels, TX 78130
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    New Braunfels Medical/Professional Office Space
    $36 SF/Yr
    20,128 SF

    New Braunfels Medical/Professional Office Space

    New medical and professional office building for lease in New Braunfels.

    671 Ridge Hill Dr, New Braunfels, TX 78130
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    Class A Medical Office Space
    $25 SF/Yr
    18,600 SF

    Class A Medical Office Space

    New Class A medical/retail space for lease, ready for occupancy.

    1750 East Common Street, New Braunfels, TX 78130
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    Renovated Office Space in Oak Hills
    $25 SF/Yr
    4,540 SF

    Renovated Office Space in Oak Hills

    Medical/Office space for lease, convenient location, undergoing renovation.

    1735 Babcock Rd, San Antonio, TX
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    Medical Office on Broadway Street
    $28 SF/Yr
    2,515 SF

    Medical Office on Broadway Street

    Second-generation medical office space available for lease.

    8005 Broadway St, San Antonio, TX
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    Medical/Office Space Near Methodist Hospital
    $18 SF/Yr

    Medical/Office Space Near Methodist Hospital

    Medical/office space available near Methodist Stone Oak Hospital.

    116 Gallery Cir, San Antonio, TX 78258
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    Medical Office Space Available
    $18 SF/Yr
    12,014 SF

    Medical Office Space Available

    Office space for rent near Methodist Stone Oak Hospital.

    116 Gallery Cir, San Antonio, TX 78258
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    Medical Office Space For Lease
    Contact for pricing

    Medical Office Space For Lease

    First-floor medical office space with Loop 1604 visibility.

    4515 N Loop 1604 W, San Antonio, TX 78249
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    Office/Medical Office Space Available
    Contact for pricing
    5,078 SF

    Office/Medical Office Space Available

    Office and medical suites for lease with immediate occupancy.

    876 Loop 337, New Braunfels, TX 78130
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    Versatile Space in New Braunfels
    $28 SF/Yr
    3,800 SF

    Versatile Space in New Braunfels

    Spacious property ideal for retail, office, or medical use.

    901 Loop 337, New Braunfels, TX
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    Medical Office Sublease Opportunity
    $21 SF/Yr
    7,646 SF

    Medical Office Sublease Opportunity

    Sublease opportunity: 7,646 SF fully built-out medical space.

    700 E Sonterra Blvd, San Antonio, TX
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    Medical Office Space IH-35 Frontage
    $22 SF/Yr
    1,424 SF

    Medical Office Space IH-35 Frontage

    Shell space in Texas MedClinic-anchored medical office building for lease.

    958 N Interstate 35, New Braunfels, TX
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    Modernized Medical Office Building
    Contact for pricing
    25,000 SF

    Modernized Medical Office Building

    Extensively renovated medical office building with ambulatory surgical center.

    1804 NE Loop 410, San Antonio, TX
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    Medical Office Space Available
    $16 SF/Yr
    12,342 SF

    Medical Office Space Available

    Move-in ready medical office space in San Antonio.

    6623 S Zarzamora St, San Antonio, TX
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    Dominion Drive Office Space Available
    $30 SF/Yr
    1,489 SF

    Dominion Drive Office Space Available

    Professionally designed office space near The Dominion Country Club.

    4 Dominion Drive, San Antonio, TX
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    Alamo Heights Medical Office Space
    Contact for pricing
    2,627 SF

    Alamo Heights Medical Office Space

    Class A medical office space for lease in San Antonio.

    3338 Oakwell Ct, San Antonio, TX
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    Turnkey Medical Space Available
    $24 SF/Yr
    1,720 SF

    Turnkey Medical Space Available

    Second-generation medical space in a vibrant trade area.

    2327 Sw Military Dr, San Antonio, TX
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    Medical/Office Space Near I-10
    $30 SF/Yr
    27,675 SF

    Medical/Office Space Near I-10

    27,675 SF medical/office space undergoing renovation, completion mid-2025.

    9100 McDermott Fwy, San Antonio, TX
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    Medical Office Space Available
    Contact for pricing
    115,918 SF

    Medical Office Space Available

    Medical office space for rent on hospital campus.

    1139 E Sonterra Blvd, San Antonio, TX
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    Medical Office in Stone Oak
    $31 SF/Yr
    2,325 SF

    Medical Office in Stone Oak

    Medical office space available in a growing San Antonio area.

    19114 US-281, San Antonio, TX 78221
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    Medical Office Space Available
    Contact for pricing
    67,026 SF

    Medical Office Space Available

    Medical office space for rent on Methodist Main campus.

    4330 MEDICAL DR, San Antonio, TX
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    Comal County, TX Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Comal County, TX with 88 listings featured on our commercial real estate exchange. The current inventory includes 2,357,859,240 square feet of properties with an estimated lease value of $273 SF/Yr.

    Estimated lease rates for Medical Office Space in Comal County, TX begin at $16 SF/Yr, with an average of $22 SF/Yr and extend to $28 SF/Yr.
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    Browse Medical Office Space for Lease Near Comal, TX

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