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    Hesperia, CA Medical Office Space for Lease

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    Medical Office Space Available
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    678 SF

    Medical Office Space Available

    15462 Main St, Hesperia, CA 92345

    Private office space in medical professional building for rent.

    • Private office space within an attractive medical professional building.
    • Landlord covers trash, water, common area expenses (parking lot, landscaping).
    • Private exterior entrance.
    • Includes a large open office area, a private office, and a restroom.
    • Good visibility and easy access to Main St.
    Updated: Mar 18, 2025
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    Freestanding Medical Office Sublease Opportunity
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    5,200 SF

    Freestanding Medical Office Sublease Opportunity

    11959 Mariposa Rd, Hesperia, CA 92345

    Single-story medical office building available for sublease in Hesperia, CA.

    • Freestanding, Single‑Story Medical Office Building (5,200 SF)
    • Turnkey opthamology space with existing build‑out
    • Current lease in place through 2/28/33
    • Immediate access to I‑15, high‑traffic location with visibility
    • Prime location within 3 miles of Desert Valley Hospital
    Updated: Aug 15, 2025
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    Hesperia Center Retail/Office Suites
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    2,651 SF

    Hesperia Center Retail/Office Suites

    Retail and office suites available for lease in Hesperia.

    16455 Main St, Hesperia, CA 92345
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    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 3 Active listings in Hesperia, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Victorville Professional Office Space
    $9,837 /Mo
    4,186 SF

    Victorville Professional Office Space

    Well-maintained office building in central Victorville, ideal for medical/office.

    12998 Hesperia Rd 203, Victorville, CA 92395
    View details
    Versatile Space for Healthcare Providers
    $1.00 SF/Yr
    15,042 SF

    Versatile Space for Healthcare Providers

    Well-maintained 3,000 SF suite ideal for healthcare or professional offices.

    18031 HWY 18 Suite #B, Apple Valley, CA 92307
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    Premium Office Space Available
    Contact for pricing
    3,000 SF

    Premium Office Space Available

    Nearly 3,000 sq. ft. office space in Apple Valley.

    19341 Bear Valley Rd, Apple Valley, CA 92308
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    Prime Retail and Office Spaces
    Contact for pricing
    18,200 SF

    Prime Retail and Office Spaces

    Retail and office spaces available near the 15 freeway.

    12550 Amargosa Rd, Victorville, CA 92392
    View details

    Explore Similar Spaces for Sale in Hesperia, CA

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Medical Office Suite For Sale
    Contact for pricing
    15,520 SF

    Medical Office Suite For Sale

    Medical office suite in a professionally managed building.

    17450 Street Unit H Unit H, Hesperia, CA 92345
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land for Lease
    Contact for pricing

    Commercial Land for Lease

    Commercial land with high traffic counts available for lease.

    15901 Main St, Hesperia, CA 92345
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    Retail Space on Main Street
    Contact for pricing
    1,712 SF

    Retail Space on Main Street

    Retail space available on Hesperia's Main Street retail corridor.

    14101 Main St, Hesperia, CA 92345
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    Hesperia Land with Shop and Yard
    $0.12 SF/Yr
    375,052 SF

    Hesperia Land with Shop and Yard

    8.61 acres available with shop, house/office, and canopies.

    9927 C Ave, Hesperia, CA 92345
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    Hesperia Land for Lease
    Contact for pricing
    80,150 SF

    Hesperia Land for Lease

    1.84 acres of commercial land available for lease.

    NW of Mariposa Rd and Sunset St, Hesperia, CA
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    Hesperia, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Hesperia, CA with 3 listings featured on our commercial real estate exchange. The current inventory includes 0 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Medical Office Space in Hesperia, CA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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