Murrysville, PA Medical Office Space for sale

Updated: Dec 3, 2025

Murrysville Office Building For Sale

4212 Old William Penn Hwy, Murrysville, PA 15668

$540,000

1,450 sqft 0.45 AC lot

High‑traffic location in the heart of Murrysville with over 6,000 vehicles passing daily.
Suitable for medical practices, chiropractic offices, med‑spas, or other businesses.
Solid brick two‑story building with 2,700 total square feet.
First floor features a large reception area, multiple exam rooms, office space, kitchenette, and two restrooms (one ADA accessible).
Second floor includes a waiting room, exam rooms, office space, lab area, and break room.

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This listing looks promising.

Here's a quick look at some key insights for

4212 Old William Penn Hwy, Murrysville, PA, 15668-1901

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Est. Cap Rate

3.4%
NOI ÷ price
Est. NOI

$19K
Annual
Mortgage

$415K
Sep 2024
Last Sold

May 2024
$487K

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Updated: Jan 26

Retail Center on High Visibility Corner

3700 Old William Penn Hwy, Murrysville, PA 15668

$699,000

1.34 AC lot

High‑visibility corner location at Rt 22 and Old William Penn Hwy
Ideal opportunity for an owner‑user
Two vacant units, one built out for medical use
Excellent signage opportunities with internally lit signs
Handicap accessible units with convenient front parking

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Two-Story Office Building

4212 Old William Penn Hwy, Murrysville, PA 15668

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2,700 sqft

Two-story office building with separate utilities and exam-room layout suited to medical or med-spa use.

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Medical Office Building with Multi-Tenant

4262 Old William Penn Highway, Murrysville, PA 15668

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22,286 sqft

Two-story medical office building with 89% occupancy and a diversified physician and specialty rent roll.

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Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 4 Active listings in Murrysville, PA, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Monroeville Commercial Space For Sale

4351 Old William Penn Hwy, Monroeville, PA 15146

$665,000

3,200 sqft 1.90 AC lot

High-visibility commercial space in a sought-after Monroeville location.

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Mixed-Use Multi-Family Building

848 Pittsburgh St, Springdale, PA 15144

$380,000

0.08 AC lot

Mixed-use property with two street-facing commercial spaces and upper-level apartment potential for about five units.

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Medical Office Building with 4 Floors

200 James Pl, Monroeville, PA 15146

Contact for pricing

30,933 sqft

Four-story medical office building with elevator access, common restrooms, and on-site parking.

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Mixed-Use Building with Apartment

848 Pittsburgh Street, Springdale, PA 15144

$380,000

Front commercial spaces face Pittsburgh Street, with upper-level residential space set up for short-term rental.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Cleared Level Commercial Land Parcel

State Rd 130, Irwin, PA 15642

$700,000

1.01 AC lot

A level, cleared 1-acre site along Route 130 with public utilities available and strong visibility for development.

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Vacant Lot Prime Location

105 Welton Drive, Cumberland, MD 21502

$699,900

1.46 AC lot

1.46 acre vacant lot, convenient access, great possibilities.

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Prime Corner Lot Opportunity

2937 Woodlawn Avenue Northwest, Canton, OH 44708

$1,250,000

2.39 AC lot

High-visibility commercial land in thriving Jackson Township.

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Prime Commercial Land Opportunity, Elkins

Plantation Drive, Elkins, WV 26241

$2,000,000

11.86 AC lot

11.86 acres of commercial land adjacent to Hampton Inn.

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Murrysville, PA Medical Office Space Market Trends and Statistics

Explore 4 medical office space for sale in Murrysville, PA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 26,436 square feet of properties for sale, with an estimated market value of $1,239,000.

Sale prices for medical spaces in Murrysville, PA start at $540,000, averaging $619,500, and reaching up to $699,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
15668	$619.5K

Neighborhood

Average Price

15668

$619.5K

Murrysville, PA Medical Office Space for Sale

4212 Old William Penn Hwy, Murrysville, PA 15668

3700 Old William Penn Hwy, Murrysville, PA 15668

4212 Old William Penn Hwy, Murrysville, PA 15668

4262 Old William Penn Highway, Murrysville, PA 15668