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Clyde, NC Medical Office Space for Sale

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Custom Designed Medical Office Building
$1,900,000
11,260 SF

Custom Designed Medical Office Building

540 Hospital Drive, Clyde, NC 28721

Multipurpose 11,000+ sq ft building near I-40 and hospital.

  • Multipurpose 11,000+ sq ft custom‑designed building.
  • Prime location with high traffic count and close proximity to Interstate 40.
  • Minutes from Duke Lifepoint Hospital and other medical practices.
  • Quality construction by Charles Lanning, designed by Randy Cunningham.
  • Luxurious interior suitable for medical office or custom home.
Updated: Jul 24, 2025
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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 1 Active listings in Clyde, NC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 20 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Historic Waynesville Commercial Landmark
$1,925,000
1.38 Acres

Historic Waynesville Commercial Landmark

Haywood County landmark with business and residential potential.

123 S Main Street, Waynesville, NC 28786
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Patton Avenue Commercial Building
$625,000

Patton Avenue Commercial Building

Charming office building on Patton Avenue, Asheville, for sale.

1473 Patton Avenue, Asheville, NC 28806
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West Asheville Medical Office Assemblage
$962,200
2,290 SF

West Asheville Medical Office Assemblage

Medical office with development opportunity in West Asheville.

1708 & 1710 Old Haywood Road, Asheville, NC 28806
View details
Medical Office Park For Sale
$6,500,000
38,421 SF

Medical Office Park For Sale

Leased medical office park in western North Carolina.

90 Haywood Office Park, Waynesville, NC 28785
View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Near Western Carolina
$989,000
0.90 Acres

Commercial Land Near Western Carolina

0.9 acre commercial land near Western Carolina University.

628 E Main Street, Sylva, NC 28779
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Commercial Opportunity in Straus Park
$69,000
0.20 Acres

Commercial Opportunity in Straus Park

Premier commercial land in Brevard's Straus Park community.

42 Park Place, Brevard, NC 28712
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Commercial Land Near Medical Center
$299,000
0.80 Acres

Commercial Land Near Medical Center

Highly visible commercial land suitable for medical offices or services.

Macon Center Drive lot: B, Franklin, NC 28734
View details
Sevierville Development Land Opportunity
$7,128,000
11.88 Acres

Sevierville Development Land Opportunity

Prime 11.88-acre development land near medical and RV facilities.

Middle Creek Road, Sevierville, TN 37862
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Explore Off-Market Properties in Clyde, NC

Consider similar Off-Market properties in Clyde, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

78 Nelson St

78 Nelson St

MEDICAL BUILDING • 4,384 SF
Value Estimation by Request
78 Nelson St, Clyde, NC 28721-9661
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581 Leroy George Dr

581 Leroy George Dr

MEDICAL BUILDING • 16,836 SF
Value Estimation
$895,000
581 Leroy George Dr, Clyde, NC 28721-8084
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40 Nelson St

40 Nelson St

MEDICAL BUILDING • 2,621 SF
Value Estimation
$690,000
40 Nelson St, Clyde, NC 28721-9661
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486 Hospital Dr

486 Hospital Dr

MEDICAL BUILDING • 6,765 SF
Value Estimation by Request
486 Hospital Dr, Clyde, NC 28721-8026
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243 Jones Cv Rd

243 Jones Cv Rd

MEDICAL BUILDING • 2,372 SF
Value Estimation by Request
243 Jones Cv Rd, Clyde, NC 28721-9483
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11 Falcon Crst Ln

11 Falcon Crst Ln

MEDICAL BUILDING • 5,420 SF
Value Estimation by Request
11 Falcon Crst Ln, Clyde, NC 28721-6620
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490 Hospital Dr

490 Hospital Dr

MEDICAL BUILDING • 5,404 SF
Value Estimation by Request
490 Hospital Dr, Clyde, NC 28721-8026
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40 Brettwood Trce

40 Brettwood Trce

MEDICAL BUILDING • 4,977 SF
Value Estimation by Request
40 Brettwood Trce, Clyde, NC 28721-8021
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32 Physician Dr

32 Physician Dr

MEDICAL BUILDING • 6,202 SF
Value Estimation by Request
32 Physician Dr, Clyde, NC 28721-8486
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177 Paragon Pkwy

177 Paragon Pkwy

Medical Office Space
Value Estimation by Request
177 Paragon Pkwy, Clyde, NC 28721
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49 Spicewood Dr

49 Spicewood Dr

MEDICAL BUILDING • 6,910 SF
Value Estimation by Request
49 Spicewood Dr, Clyde, NC 28721
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16 Physician Dr

16 Physician Dr

MEDICAL BUILDING • 3,048 SF
Value Estimation by Request
16 Physician Dr, Clyde, NC 28721-8486
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8 Physician Dr

8 Physician Dr

MEDICAL BUILDING • 6,633 SF
Value Estimation by Request
8 Physician Dr, Clyde, NC 28721-8486
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42 Physician Dr

42 Physician Dr

MEDICAL BUILDING • 6,250 SF
Value Estimation by Request
42 Physician Dr, Clyde, NC 28721
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11 Park Ter Dr

11 Park Ter Dr

MEDICAL BUILDING • 8,370 SF
Value Estimation by Request
11 Park Ter Dr, Clyde, NC 28721-7445
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600 Hospital Dr

600 Hospital Dr

MEDICAL BUILDING • 4,006 SF
Value Estimation by Request
600 Hospital Dr, Clyde, NC 28721-8024
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540 Hospital Dr

540 Hospital Dr

MEDICAL BUILDING • 7,878 SF
Value Estimation by Request
540 Hospital Dr, Clyde, NC 28721-8027
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63 Haywood Park Dr

63 Haywood Park Dr

MEDICAL BUILDING • 7,592 SF
Value Estimation by Request
63 Haywood Park Dr, Clyde, NC 28721-4404
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6750 Carolina Blvd

6750 Carolina Blvd

MEDICAL BUILDING • 8,724 SF
Value Estimation by Request
6750 Carolina Blvd, Clyde, NC 28721-7052
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15 Brettwood Trce

15 Brettwood Trce

MEDICAL BUILDING • 4,878 SF
Value Estimation by Request
15 Brettwood Trce, Clyde, NC 28721-8021
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Clyde, NC Medical Office Space Investment Opportunities Market Analysis

Explore 21 medical office space for sale in Clyde, NC on our real estate platform. These investment opportunities span a total of 125,248 square feet of properties for sale, with an estimated market value of $1,525,000.

Sale prices for medical spaces in Clyde, NC start at $260,000, averaging $381,250, and reaching up to $600,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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