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    Clayton, NC Medical Office Space for Sale

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    Commercial Land in Clayton, NC
    $167,000
    0.42 Acres

    Commercial Land in Clayton, NC

    141 State Ave, Clayton, NC 27520

    Prime commercial land with B-3 zoning in Clayton, North Carolina.

    • Prime commercial location in the heart of Clayton with excellent visibility near US‑70 Business.
    • Flexible B‑3 zoning suitable for various commercial uses (medical, retail, food/beverage, office).
    • Two adjacent parcels totaling +/-0.42 acres with city water and sewer.
    • High‑traffic location surrounded by growing residential neighborhoods, retail hubs, and medical uses.
    • Conceptual site plans available for a +/-4,000 SF medical/dental/eye clinic or a +/-2,500 SF cafe/bakery.
    Updated: Jan 14
    View details
    Versatile Commercial Building in Clayton, NC
    $1,500,000
    10,010 SF

    Versatile Commercial Building in Clayton, NC

    100 Cunningham Ln, Clayton, NC 27527

    9,489 sq ft commercial building on 0.85 acres for sale.

    • Income‑producing property with five units currently leased to tenants.
    • 2,736 sq. ft. of available space for owner‑user or additional rental income.
    • Located in the desirable Riverwood Athletic Community.
    • Flexible commercial zoning allows for a wide variety of uses.
    • Ample parking available.
    Updated: Sep 12, 2025
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    Medical Office Building Near Downtown
    Contact for pricing
    20,000 SF

    Medical Office Building Near Downtown

    Two-story medical office building near downtown Clayton for sale.

    890 S Lombard St, Clayton, NC 27520
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    Medical Park Development Opportunity
    Contact for pricing
    70,000 SF

    Medical Park Development Opportunity

    Medical park buildings for sale with highway visibility.

    2003 Hwy 42 West, Clayton, NC 27520
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    Clayton Medical Office Building
    Contact for pricing
    20,000 SF

    Clayton Medical Office Building

    Prime Medical Office Space in Clayton, NC

    890 Lombard St, Clayton, NC 27520
    View details
    Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 5 Active listings in Clayton, NC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 39 Off-Market properties to explore as potential leads, plus 3 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Garner Retail Opportunity
    Contact for pricing
    1.56 Acres

    Prime Garner Retail Opportunity

    High-visibility NC Hwy 42 retail site, build-to-suit.

    42 & Old Drugstore Rd, Garner, NC 27529
    View details
    Garner Retail Outparcel Investment
    Contact for pricing
    1.35 Acres

    Garner Retail Outparcel Investment

    High-visibility NC Hwy 42 retail site.

    42 & Old Drugstore Rd, Garner, NC 27529
    View details
    Medical Office Condo Investment Opportunity
    $900,000
    3,128 SF

    Medical Office Condo Investment Opportunity

    Well-maintained medical office condo in prime Raleigh location for sale.

    3396 Six Forks Rd, Raleigh, NC 27609
    View details
    Medical Office Condo For Sale
    $900,000
    3,128 SF

    Medical Office Condo For Sale

    3,128 SF medical office condo in prime Raleigh location.

    3396 Six Forks Rd, Raleigh, NC 27609
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lots on Highway 42
    $299,900
    0.62 Acres

    Commercial Lots on Highway 42

    Two vacant commercial lots, cleared and flat, ready to build.

    212 Butternut Ln, Clayton, NC 27520
    View details
    Cleared Commercial Land in Clayton
    $89,000
    0.24 Acres

    Cleared Commercial Land in Clayton

    0.24-acre corner lot zoned for office and institutional uses.

    117 Butternut Ln, Clayton, NC 27520
    View details
    Commercial Land in Growing Clayton
    $89,000
    0.26 Acres

    Commercial Land in Growing Clayton

    Cleared commercial lot in Clayton, NC, ready for development.

    113 Butternut Ln, Clayton, NC 27520
    View details

    Explore Off-Market Properties in Clayton, NC

    Consider similar Off-Market properties in Clayton, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2003 Nc-42

    2003 Nc-42

    Medical Office Space • 70,000 SF
    Value Estimation by Request
    2003 Nc-42, Clayton, NC 27520
    View details
    555 Medical Park Pl

    555 Medical Park Pl

    MEDICAL BUILDING • 38,428 SF
    Value Estimation
    $1,975,000
    555 Medical Park Pl, Clayton, NC 27520-2174
    View details
    100 Butternut Ln

    100 Butternut Ln

    MEDICAL BUILDING • 5,302 SF
    Value Estimation
    $590,000
    100 Butternut Ln, Clayton, NC 27520-5868
    View details
    649 Guy Rd

    649 Guy Rd

    MEDICAL BUILDING • 6,092 SF
    Value Estimation
    $815,000
    649 Guy Rd, Clayton, NC 27520-4173
    View details
    Guy Rd

    Guy Rd

    MEDICAL BUILDING • 2,920 SF
    Value Estimation by Request
    Guy Rd, Clayton, NC 27520
    View details
    900 Lombard St

    900 Lombard St

    MEDICAL BUILDING • 7,290 SF
    Value Estimation
    $835,000
    900 Lombard St, Clayton, NC 27520-2737
    View details
    920 Lombard St

    920 Lombard St

    MEDICAL BUILDING • 9,800 SF
    Value Estimation
    $1,850,000
    920 Lombard St, Clayton, NC 27520-2728
    View details
    2196 Nc Hwy 42nd W

    2196 Nc Hwy 42nd W

    MEDICAL BUILDING • 11,000 SF
    Value Estimation
    $6,110,000
    2196 Nc Hwy 42nd W, Clayton, NC 27520-8343
    View details
    37 Pineville Blvd

    37 Pineville Blvd

    MEDICAL BUILDING • 9,975 SF
    Value Estimation
    $1,115,000
    37 Pineville Blvd, Clayton, NC 27527-9355
    View details
    45 Shotwell Rd

    45 Shotwell Rd

    MEDICAL BUILDING • 4,616 SF
    Value Estimation
    $580,000
    45 Shotwell Rd, Clayton, NC 27520-5501
    View details
    5400 Barber Ml Rd

    5400 Barber Ml Rd

    MEDICAL BUILDING • 3,200 SF
    Value Estimation by Request
    5400 Barber Ml Rd, Clayton, NC 27520-7260
    View details
    31 Oleander Dr

    31 Oleander Dr

    MEDICAL BUILDING • 8,577 SF
    Value Estimation
    $1,165,000
    31 Oleander Dr, Clayton, NC 27527-4561
    View details
    300 Guy Rd

    300 Guy Rd

    MEDICAL BUILDING • 5,325 SF
    Value Estimation
    $600,000
    300 Guy Rd, Clayton, NC 27520-6790
    View details
    11618 Us 70th Business W Hwy

    11618 Us 70th Business W Hwy

    MEDICAL BUILDING • 31,536 SF
    Value Estimation
    $5,495,000
    11618 Us 70th Business W Hwy, Clayton, NC 27520-2275
    View details
    201 Main St

    201 Main St

    MEDICAL BUILDING • 1,200 SF
    Value Estimation by Request
    201 Main St, Clayton, NC 27520-2449
    View details
    101 Winding Wood Dr

    101 Winding Wood Dr

    MEDICAL BUILDING • 2,750 SF
    Value Estimation by Request
    101 Winding Wood Dr, Clayton, NC 27520-4493
    View details
    890 Lombard St

    890 Lombard St

    Medical Office Space • 20,000 SF
    Value Estimation by Request
    890 Lombard St, Clayton, NC 27520
    View details
    452 Shotwell Rd

    452 Shotwell Rd

    MEDICAL BUILDING • 3,448 SF
    Value Estimation by Request
    452 Shotwell Rd, Clayton, NC 27520-7397
    View details
    105 Ellington St

    105 Ellington St

    MEDICAL BUILDING • 1,400 SF
    Value Estimation by Request
    105 Ellington St, Clayton, NC 27520-2305
    View details

    Clayton, NC Medical Office Space Investment Opportunities Market Analysis

    Explore 44 medical office space for sale in Clayton, NC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 851,412 square feet of properties for sale, with an estimated market value of $32,872,000.

    Sale prices for medical spaces in Clayton, NC start at $145,000, averaging $2,528,615, and reaching up to $12,710,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Medical Office Space for Sale Near Clayton, NC

    Popular Searches in Clayton, NC

    Most Searched ZIP Codes in Clayton, NC

    • 27520
    • 27527

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