Add Listing
    Clayton, NC
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Clayton, NC Medical Office Space for Lease

    Notify Me
    List
    Map
    Garner, NC Smithfield, NC Knightdale, NC
    Medical Office Space For Lease
    $29 SF/Yr
    10,000 SF

    Medical Office Space For Lease

    29 HealthPark Way, Clayton, NC 27520

    Medical office space available near Johnston UNC Health Clayton Hospital.

    • Located across from Johnston UNC Health Clayton Hospital
    • Governmental wastewater allocation secured
    • Generous Upfit Allowance
    • Prime Building Signage on Highway 42
    • Signalized Ingress and Egress
    Updated: Mar 6
    View details
    Medical Office Space in Clayton
    $30 SF/Yr
    29,588 SF

    Medical Office Space in Clayton

    166 Springbrook Ave, Clayton, NC 27520

    Class A medical office space available for lease in Clayton.

    • Class A medical office space in a desirable Clayton, NC location.
    • ±6,435 SF suite with flexible occupancy options: immediate availability for ±3,000 SF of shell space and ±3,000 SF occupied by WakeMed (available 9/1/26).
    • Located in an established healthcare corridor with strong medical co‑tenancy.
    • Easy access to Downtown Clayton, Johnston Health, and surrounding residential communities.
    • Conveniently located near US‑70 Business and minutes from I‑40, providing excellent regional connectivity.
    Updated: Nov 26, 2025
    View details
    Medical Office Building Near Downtown
    Contact for pricing

    Medical Office Building Near Downtown

    Two-story medical office building with ground-level entries near downtown.

    890 S Lombard, Clayton, NC 27520
    View details
    Medical Office Building Near Downtown
    Contact for pricing
    10,000 SF

    Medical Office Building Near Downtown

    Two-story medical office building near downtown Clayton available for lease.

    890 S Lombard St, Clayton, NC 27520
    View details
    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 4 Active listings in Clayton, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space For Lease
    $45 SF/Yr
    31,720 SF

    Medical Office Space For Lease

    Future medical office space in prime Garner location.

    803 Morris Dr, Garner, NC 27529
    View details
    Medical Office Near WakeMed Raleigh
    $25 SF/Yr
    14,016 SF

    Medical Office Near WakeMed Raleigh

    Single-story medical office building steps from WakeMed Raleigh.

    3305 Sungate Blvd, Raleigh, NC 27610
    View details
    Retail and Medical Office Spaces
    Contact for pricing

    Retail and Medical Office Spaces

    Retail and medical spaces in Raleigh, estimated delivery Q3 2025.

    5100 Forestville Rd, Raleigh, NC 27604
    View details
    Medical Office Development Opportunity
    Contact for pricing
    9,100 SF

    Medical Office Development Opportunity

    1.01-acre site ideal for medical office development in Garner, NC.

    225 Glen Road, Garner, NC 27529
    View details

    Similar Spaces for Sale in Clayton, NC

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Versatile Commercial Building in Clayton, NC
    $1,500,000
    10,010 SF
    Versatile Commercial Building in Clayton, NC

    9,489 sq ft commercial building on 0.85 acres for sale.

    100 Cunningham Lane, Clayton, NC 27527

    View details
    Medical Office Building Near Downtown
    Contact for pricing
    20,000 SF
    Medical Office Building Near Downtown

    Two-story medical office building near downtown Clayton for sale.

    890 S Lombard, Clayton, NC 27520

    View details
    Medical Park Development Opportunity
    Contact for pricing
    70,000 SF
    Medical Park Development Opportunity

    Medical park buildings for sale with highway visibility.

    2003 Hwy 42 West, Clayton, NC 27520

    View details
    Medical Office Building For Sale
    Contact for pricing
    20,000 SF
    Medical Office Building For Sale

    Two-story medical office building near downtown Clayton, North Carolina.

    890 S Lombard St, Clayton, NC 27520

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF

    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756
    View details
    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    Clayton, NC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Clayton, NC with 4 listings featured on our commercial real estate exchange. The current inventory includes 39,588 square feet of properties with an estimated lease value of $59 SF/Yr.

    Estimated lease rates for Medical Office Space in Clayton, NC begin at $29 SF/Yr, with an average of $29 SF/Yr and extend to $30 SF/Yr.
    List
    Map

    Popular Searches in Clayton, NC

    Popular Categories

    Most Searched ZIP Codes in Clayton, NC

    • 27520

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!