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    Little Elm, TX Medical Office Space for Lease

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    New Mixed-Use Development Available
    Contact for pricing
    1,350 SF

    New Mixed-Use Development Available

    2135 Oak Grove Pkwy, Little Elm, TX 75068

    Upscale professional, medical, retail, and restaurant spaces available Fall 2025.

    • Location on Oak Grove Pkwy near the entrance into Little Elm/Frisco off the fast growing 380 corridor
    • Upscale mixed use development
    • Professional / Medical Office Suites available
    • Fully Finished Out Suites
    • Three Professional / Medical Office Buildings
    Updated: May 21, 2025
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    Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 1 Active listings in Little Elm, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    West Frisco Medical Office Space
    $30 SF/Yr
    10,400 SF

    West Frisco Medical Office Space

    Modern medical suites, 1300-2600 sqft

    25663 Smotherman Rd, Frisco, TX 75033
    View details
    Frisco Office/Medical Building For Lease
    $8,167 / Mo
    118,178 SF

    Frisco Office/Medical Building For Lease

    Move-in ready office/medical building in Frisco, TX available for lease.

    425 Old Newman Rd, Frisco, TX 75036
    View details
    Medical Facility Near Hospitals
    Contact for pricing
    40,365 SF

    Medical Facility Near Hospitals

    Medical facility with easy access to hospitals and Interstate 35.

    2809 S Mayhill Rd, Denton, TX 76208
    View details
    Move-In Ready Medical Office Space
    Contact for pricing
    2,764 SF

    Move-In Ready Medical Office Space

    Medical office space adjacent to Medical City Denton.

    3324 Colorado Blvd, Denton, TX 76210
    View details

    Explore Similar Spaces for Sale in Little Elm, TX

    Consider Similar Space for Sale. We found 3 Spaces in Nearby Locations matching your search parameters.

    Prime Office/Retail Location
    $419,000
    9.70 Acres

    Prime Office/Retail Location

    Excellent location suitable for various businesses, medical use, or retail.

    2601 Little Elm Pkwy, Little Elm, TX 75068
    View details
    Modern Office Suite in Little Elm
    $430,000
    0.03 Acres

    Modern Office Suite in Little Elm

    New office suite near FM 720 and FM 423 intersection.

    2601 Little Elm Pkwy, Little Elm, TX 75068
    View details
    Restaurant/Retail and Medical Space
    Contact for pricing
    11,602 SF

    Restaurant/Retail and Medical Space

    Restaurant/Retail and Medical space available for sale.

    1180 E Eldorado Pkwy, Little Elm, TX 75068
    View details

    Little Elm, TX Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Little Elm, TX with 4 listings featured on our commercial real estate exchange. The current inventory includes 58,806,000 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Medical Office Space in Little Elm, TX begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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