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    Knoxville, TN Medical Offices for Lease

    17 results
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    Knoxville Office Building For Lease
    Pending
    $1,925,000
    10,002 SF

    Knoxville Office Building For Lease

    4624 Chambliss Ave, Knoxville, TN 37919

    Well-maintained office building with modern upgrades, ideal for various uses.

    • Meticulously maintained and upgraded in 2021 with a new roof (with warranty), HVAC system, water heater, and Cat6 wiring.
    • 10,002 SF office building with flexible space suitable for professional, medical, or institutional users.
    • Excellent location near the University of Tennessee, Downtown Knoxville, and I‑40/I‑75.
    • Functional basement warehouse space in addition to two stories.
    • Ample on‑site parking.
    Updated: Nov 25, 2025
    View details
    Lakemoor Medical Office Space
    $11 SF/Yr
    14,500 SF

    Lakemoor Medical Office Space

    3105 Alcoa Hwy, Knoxville, TN 37920

    Knoxville medical office building, 3,300 SF available.

    • 14,500 SF single‑story medical office building in Knoxville, TN on a 2.5‑acre lot.
    • Located on high‑traffic Alcoa Highway with excellent visibility.
    • Class C building, constructed in 1987, with 3,300 SF of vacant space divisible into units ranging from 1,000‑3,300 SF.
    • Recently renovated with a new facade, roof, and parking lot ($300,000 in capital improvements).
    • Zoned C‑G‑1 General Business (APN 135HB007, Knox County); ample parking.
    Updated: Dec 11, 2024
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    Bearden Hill Office/Retail Space
    $21 SF/Yr
    3,406 SF

    Bearden Hill Office/Retail Space

    Kingston Pike, Knoxville - 3,406 sq ft

    6601 Kingston Pike, Knoxville, TN 37919
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    Chapman Hwy Medical Office Space
    $15 SF/Yr
    78,968 SF

    Chapman Hwy Medical Office Space

    Knoxville medical office building, high visibility

    4512 Chapman Hwy, Knoxville, TN 37920
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    Knoxville Office/Medical Space Available
    $998,000
    3,755 SF

    Knoxville Office/Medical Space Available

    Office or medical space with ample parking, convenient location.

    2507 Mineral Springs Ave, Knoxville, TN 37917
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    Office Suites with Pellissippi Visibility
    $23 SF/Yr
    7,200 SF

    Office Suites with Pellissippi Visibility

    Office suites available with high visibility and flexible buildouts.

    10641 Braden Dickey Ln, Knoxville, TN 37932
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    Professional Office Space in Knoxville
    $18 SF/Yr
    7,755 SF

    Professional Office Space in Knoxville

    Sub-lease available in the heart of Cedar Bluff.

    8930 Cross Park Dr, Knoxville, TN 37923
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    Professional Office/Medical Space For Lease
    $18 SF/Yr
    2,054 SF

    Professional Office/Medical Space For Lease

    Well-appointed office space with flexible layout, ideal for various practices.

    1341 Branton Blvd, Knoxville, TN 37922
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    Turn-Key Medical Office Space
    $1,304,600
    4,744 SF

    Turn-Key Medical Office Space

    4,744 SF medical office in West Knoxville, TN.

    6348 Lonas Spring Dr, Knoxville, TN 37909
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    Farragut Office Space on Kingston
    $18 SF/Yr
    1,600 SF

    Farragut Office Space on Kingston

    1,600 SF office space in the heart of Farragut.

    10805 Kingston Pike, Knoxville, TN 37934
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    New Dental/Professional Office Space
    $28 SF/Yr
    9,335 SF

    New Dental/Professional Office Space

    New development in Karns, near schools, prominent signage.

    7693 Oak Ridge Hwy, Knoxville, TN 37931
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    Turn-Key Medical Facility For Lease
    $18 SF/Yr
    7,927 SF

    Turn-Key Medical Facility For Lease

    Ready-to-launch medical clinic with exam and X-ray rooms.

    315 Gill Ave, Knoxville, TN 37917
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    Medical Office Space in Farragut
    $24 SF/Yr
    2,215 SF

    Medical Office Space in Farragut

    Medical office space available for rent in Farragut, TN.

    116 Concord Rd, Farragut, TN 37934
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    Kingston Pike Office Space Available
    $23 SF/Yr
    2,200 SF

    Kingston Pike Office Space Available

    First floor office space with multiple rooms and open area.

    8874 Kingston Pike, Knoxville, TN 37923
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    Professional/Medical Office Center For Rent
    $34 SF/Yr
    3,000 SF

    Professional/Medical Office Center For Rent

    New professional/medical office center with high visibility, available Summer/Fall 2025.

    Dutchtown Rd, Knoxville, TN 37923
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    West Knoxville Professional Office Suites
    $23 SF/Yr
    11,015 SF

    West Knoxville Professional Office Suites

    Professional office suites for lease in prime West Knoxville location.

    9950 Kingston Pike, Knoxville, TN 37922
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    Renovated Office Space Near Downtown
    $5,500 / Mo
    3,148 SF

    Renovated Office Space Near Downtown

    Partially furnished 3,148 SF dental/medical office space for rent.

    2607 Kingston Pike, Knoxville, TN 37919
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    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 17 Active listings in Knoxville, TN, we suggest exploring alternatives. Similar 12 Properties for Sales.

    Explore Similar Spaces for Sale in Knoxville, TN

    Consider Similar Space for Sale. We found 12 Spaces in Nearby Locations matching your search parameters.

    Former Veterinary Office For Sale
    $725,000
    3,400 SF

    Former Veterinary Office For Sale

    3,400 SF office building suitable for medical or office use.

    7426 Maynardville Pike, Knoxville, TN 37938
    View details
    Turn-Key Medical Office in Knoxville
    $1,304,600
    4,744 SF

    Turn-Key Medical Office in Knoxville

    4,744 SF medical office in West Knoxville for sale.

    6348 Lonas Knoxville, Knoxville, TN 37909
    View details
    West Knoxville Commercial Property
    $1,700,000
    10,182 SF

    West Knoxville Commercial Property

    10,182 SF commercial property in West Knoxville for sale.

    430 Montbrook Ln, Knoxville, TN 37919
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    Knoxville Medical Office Space Available
    Contact for pricing
    32,302 SF

    Knoxville Medical Office Space Available

    Medical office space for sale in West Knoxville's Cedar Bluff.

    9051 Executive Park Dr, Knoxville, TN 37923
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    West Knoxville Medical Office Space
    $799,000
    3,000 SF

    West Knoxville Medical Office Space

    3,000 SF medical office in high-activity office park.

    312 Prosperity Dr, Knoxville, TN
    View details
    Medical/Office Space Near Parkwest Hospital
    $820,000
    3,900 SF

    Medical/Office Space Near Parkwest Hospital

    3,900 SF open space suitable for medical or office use.

    10133 Sherrill Dr, Knoxville, TN
    View details
    New Medical Office Space Available
    Contact for pricing
    3,200 SF

    New Medical Office Space Available

    3,200 SF to-be-constructed medical office space for sale.

    Bexhill Dr, Knoxville, TN 37922
    View details

    Knoxville, TN Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in Knoxville, TN with 29 listings featured on our commercial real estate exchange. The current inventory includes 6,722,309,880 square feet of properties with an estimated lease value of $295 SF/Yr.

    Estimated lease rates for Medical offices in Knoxville, TN begin at $11 SF/Yr, with an average of $21 SF/Yr and extend to $34 SF/Yr.
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    Popular Searches in Knoxville, TN

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    Most Searched ZIP Codes in Knoxville, TN

    • 37919
    • 37923
    • 37917
    • 37920
    • 37922
    • 37934
    • 37909
    • 37931
    • 37932
    • 37916

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