Oklahoma County, OK Medical Office Space for Rent & Lease

Updated: Sep 24, 2025

Renovated Medical Office Space

2812 W Hefner Road, Oklahoma City, OK 73120

$2,200/Mo

3,024 sqft 0.29 AC lot

3,024 SF medical office property with two units
Each unit offers over 1,500 square feet
East unit updated with new paint, flooring, and lighting
ADA‑compliant areas throughout the renovated east unit
Located at Hefner Road and May Avenue in Oklahoma City

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Updated: Jul 28

Medical Office Space with Clinic Layout

501 E 15th St Unit 101, Edmond, OK 73013

$3,960/Mo

4,096 sqft

2,500 SF medical office suite
Four clinic rooms plus a dedicated nurse’s station
Lobby and receptionist office at the suite entrance
Large open area for cubicles or office equipment
Private office, breakroom/laundry room, and two bathrooms

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Move-In Ready Office Suites

1409 NW 122nd Street Unit: Suite A, Oklahoma City, OK 73114

$2,500/Mo

1,550 sqft

Two professionally designed office suites are available, each with a reception area, private offices, restrooms, and break room.

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Medical Office with X-Ray Room

4525 S. Klein Avenue, Oklahoma City, OK 73109

$3,750/Mo

The office includes clinical rooms, administrative offices, staff workspace, and a breakroom.

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Office Space Near Tinker AFB

3404 South Douglas Boulevard, Oklahoma City, OK 73150

$32 SF/Yr

12,000 sqft

Office space for rent near I-40 and Douglas Blvd.

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Secured-Entry Office and Medical Space

6300 NW Expressway, Oklahoma City, OK 73132

Contact for pricing

3,393 sqft

Tastefully updated office or medical suite with secured entry and frontage facing NW Expressway.

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Parkway Medical Building Office Space

3500 Northwest 56th Street, Oklahoma City, OK 73112

$23.50 SF/Yr

25,186 sqft

Two-story medical building with prime location and unparalleled access.

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Renovated Stand-Alone Office Building

2033 Heritage Park Dr, Oklahoma City, OK 73120

Contact for pricing

5,300 sqft

O-2-zoned property with multiple rooms, in-floor plumbing, and flexibility for professional, medical, research, or childcare uses.

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Medical Office Space with Frontage Signage

8811 E Reno Ave, Oklahoma City, OK 73110

Contact for pricing

2,456 sqft

Medical office space with available frontage signage, maintained landscaping, and ample parking in Oklahoma City.

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New Medical Office Space

3030 NW 164th St, Edmond, OK 73013

$30 SF/Yr

Clinical layout includes exam rooms, reception, staff support areas, and direct elevator access.

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Strip Mall With Medical Suite

1317 Southeast 44th Street, Oklahoma City, OK 73129

$14 SF/Yr

Retail center near a highway exit includes a completed medical suite and additional spaces for retail and service users.

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Medical Office Space with Reception

2820 Linda Ln, Oklahoma City, OK 73115

Contact for pricing

2,039 sqft

Built-out reception, waiting, administrative, and support areas suit office or soft medical use.

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Medical Office Space

5611 MOSTELLER DR, Oklahoma City, OK 73112

Contact for pricing

3,405 sqft

Medical office space is available for lease within a commercial property built in 1974.

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Split-Floor-Plan Medical Clinic

7304 N Comanche Avenue, Warr Acres, OK 73132

$500/Mo

Turn-key medical clinic with a split floor plan and a large waiting area designed for multi-practice use.

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Medical Office Space Available

4215 N. Classen Boulevard, Oklahoma City, OK 73118

$14 SF/Yr

Medical office space with exam rooms and reception area.

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Remodeled Medical Office Space

4127 NW 122nd St, Oklahoma City, OK 73120

Contact for pricing

1,788 sqft

Recently updated space offers flexible planning with an open-concept area and signage along 122nd St.

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Medical Office Space with Exam Rooms

12516 N May Ave, Oklahoma City, OK 73120

$17.50 SF/Yr

C-3 zoning permits retail, office, and service uses.

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Built-Out Medical Clinic

13900 Quailbrook Dr, Oklahoma City, OK 73134

$17 SF/Yr

Eight exam rooms, treatment space, private offices, and multiple restrooms support clinical operations.

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Open-Plan Retail Office Sublease

101 NE 82nd St, Oklahoma City, OK 73114

$23 SF/Yr

Sublease space delivered as open plan in an up-and-coming mixed-use development at 101 NE 82nd.

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Retail Suite with Exposed Brick

Oklahoma City, OK 73103

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Move-in-ready space with natural light and flexible potential for wellness, office, or creative business use.

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Medical Office Space

6001 NW 139th St, Oklahoma City, OK 73142

Contact for pricing

2,695 sqft

Fully occupied medical office property with a multi-tenant clinical roster and 2016 construction.

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Renovated Medical Office with Exam Rooms

15809 NE 23rd Street, Choctaw, OK 73020

$6,000/Mo

Recently updated layout includes clinical rooms, offices, lab, and separate staff areas.

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Medical Office Building

5101 Gaillardia Corporate Pl, Oklahoma City, OK 73142

Contact for pricing

3,343 sqft

Office space positioned near leading medical providers including Mercy and Oklahoma Heart Hospital.

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Mixed-Use Commercial Property

3401 North May Avenue, Oklahoma City, OK 73112

Contact for pricing

Flexible commercial space described for medical, retail, fitness, event, storage, and light-industrial applications.

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Oklahoma County, OK Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Oklahoma County, OK with 35 listings featured on our commercial real estate exchange. The current inventory includes 83,706 square feet of properties with an estimated lease value of $199.08.

Estimated lease rates for Medical Office Space in Oklahoma County, OK begin at $8.73 SF/Yr, with an average of $19.91 SF/Yr and extend to $32 SF/Yr.

Featured Oklahoma County Real Estate Agencies

Realmo connects you with licensed Oklahoma County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Realty Central Oklahoma

10 East Campbell Edmond, OK 73034

Phone: 14053302626

kwcentralok.yourkwoffice.com/

Prestige Real Estate Services

1401 S. Douglas suite Q Midwest City, OK 73130

Phone: 14057370202

www.prestigereservices.com

Metro Brokers of Oklahoma

2300 S. Broadway, Suite 107 Edmond, OK 73013

Phone: 14053301859