Oklahoma County, OK Medical Office Space for Rent & Lease

Updated: Sep 24, 2025

Renovated Office Units

2812 W Hefner Road, Oklahoma City, OK 73120

$2,200/Mo

3,024 sqft 0.29 AC lot

3,024 SF office property with two units
Each side measures over 1,500 square feet
East unit renovated with new paint, flooring, and lighting
ADA‑compliant areas in the east unit
Commercial zoning on 0.287 acres

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Updated: Jul 28

Medical Office Space with Clinic Layout

501 E 15th St Unit 101, Edmond, OK 73013

$3,960/Mo

4,096 sqft

2,500 SF medical office suite
Four clinic rooms plus a dedicated nurse’s station
Lobby and receptionist office at the suite entrance
Large open area for cubicles or office equipment
Private office, breakroom/laundry room, and two bathrooms

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Move-In Ready Office Suites

1409 NW 122nd Street Unit: Suite A, Oklahoma City, OK 73114

$2,500/Mo

1,550 sqft

Two professionally designed office suites are available, each with a reception area, private offices, restrooms, and break room.

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New Medical Office Space

14901 N Rockwell Ave, Oklahoma City, OK 73142

$25 SF/Yr

3,000 sqft

A dental practice facility is offered alongside adjoining land for build-to-suit development.

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1,300 - 6,500 SF of Retail Space Available in Oklahoma City, OK 73128

1600 S Morgan Rd, Oklahoma City, OK 73128

$14 SF/Yr

1,300 sqft

Growing Neighborhood Retail Center

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Medical Office with X-Ray Room

4525 S. Klein Avenue, Oklahoma City, OK 73109

$3,750/Mo

The office includes clinical rooms, administrative offices, staff workspace, and a breakroom.

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Office Space Near Tinker AFB

3404 South Douglas Boulevard, Oklahoma City, OK 73150

$32 SF/Yr

12,000 sqft

Office space for rent near I-40 and Douglas Blvd.

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New Office Units with Healthcare Plumbing

14413 N. MacArthur Boulevard, Oklahoma City, OK 73142

$26 SF/Yr

Custom-built space supports general office and healthcare users.

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Secured-Entry Office and Medical Space

6300 NW Expressway, Oklahoma City, OK 73132

Contact for pricing

3,393 sqft

Tastefully updated office or medical suite with secured entry and frontage facing NW Expressway.

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Medical Office Suite

3414 NW 135th St., Ste B, Oklahoma City, OK 73120

$18 SF/Yr

Clinical rooms, an executive office, and nursing stations provide a practice-oriented layout.

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Parkway Medical Building Office Space

3500 Northwest 56th Street, Oklahoma City, OK 73112

$23.50 SF/Yr

25,186 sqft

Two-story medical building with prime location and unparalleled access.

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New Medical Office Space

3030 NW 164th St, Edmond, OK 73013

$30 SF/Yr

Clinical layout includes exam rooms, reception, staff support areas, and direct elevator access.

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Open-Plan Retail Office Sublease

101 NE 82nd St, Oklahoma City, OK 73114

$23 SF/Yr

Sublease space delivered as open plan in an up-and-coming mixed-use development at 101 NE 82nd.

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Medical Office Space with Clear Span

12312 Market Dr, Oklahoma City, OK 73114

Contact for pricing

2,702 sqft

New construction medical/professional office space with clear-span design and flexible floor planning.

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Medical Office Space with Frontage Signage

8811 E Reno Ave, Oklahoma City, OK 73110

Contact for pricing

2,456 sqft

Medical office space with available frontage signage, maintained landscaping, and ample parking in Oklahoma City.

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Medical Office Space with Exam Rooms

12516 N May Ave, Oklahoma City, OK 73120

$17.50 SF/Yr

C-3 zoning permits retail, office, and service uses.

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Strip Mall With Medical Suite

1317 Southeast 44th Street, Oklahoma City, OK 73129

$14 SF/Yr

Retail center near a highway exit includes a completed medical suite and additional spaces for retail and service users.

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Medical Office Space

5611 MOSTELLER DR, Oklahoma City, OK 73112

Contact for pricing

3,405 sqft

Medical office space is available for lease within a commercial property built in 1974.

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Split-Floor-Plan Medical Clinic

7304 N Comanche Avenue, Warr Acres, OK 73132

$500/Mo

Turn-key medical clinic with a split floor plan and a large waiting area designed for multi-practice use.

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Medical Office Space Available

4215 N. Classen Boulevard, Oklahoma City, OK 73118

$14 SF/Yr

Medical office space with exam rooms and reception area.

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Retail Suite with Exposed Brick

Oklahoma City, OK 73103

Contact for pricing

Move-in-ready space with natural light and flexible potential for wellness, office, or creative business use.

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Medical Office Space

6001 NW 139th St, Oklahoma City, OK 73142

Contact for pricing

2,695 sqft

Fully occupied medical office property with a multi-tenant clinical roster and 2016 construction.

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Medical Office Building

5101 Gaillardia Corporate Pl, Oklahoma City, OK 73142

Contact for pricing

3,343 sqft

Office space positioned near leading medical providers including Mercy and Oklahoma Heart Hospital.

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Office Building with Ample Parking

13900 S Western Ave, Oklahoma City, OK 73170

Contact for pricing

3,010 sqft

Newly constructed office building with ample parking and visibility for healthcare or professional use.

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Oklahoma County, OK Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Oklahoma County, OK with 29 listings featured on our commercial real estate exchange. The current inventory includes 88,081 square feet of properties with an estimated lease value of $265.08.

Estimated lease rates for Medical Office Space in Oklahoma County, OK begin at $8.73 SF/Yr, with an average of $20.39 SF/Yr and extend to $32 SF/Yr.

Featured Oklahoma County Real Estate Agencies

Realmo connects you with licensed Oklahoma County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Realty Central Oklahoma

10 East Campbell Edmond, OK 73034

Phone: 14053302626

kwcentralok.yourkwoffice.com/

Prestige Real Estate Services

1401 S. Douglas suite Q Midwest City, OK 73130

Phone: 14057370202

www.prestigereservices.com

Metro Brokers of Oklahoma

2300 S. Broadway, Suite 107 Edmond, OK 73013

Phone: 14053301859