Medical Space

Oklahoma City, OK Medical Office Space for Lease

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39 properties
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Renovated Medical Office Space
Updated: Sep 24, 2025
Renovated Medical Office Space

2812 W Hefner Road, Oklahoma City, OK 73120

$2,200/Mo
3,024 sqft 0.29 AC lot
3,024 SF medical office property with two units
Each unit offers over 1,500 square feet
East unit updated with new paint, flooring, and lighting
ADA‑compliant areas throughout the renovated east unit
Located at Hefner Road and May Avenue in Oklahoma City
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Medical Office Suite with Conference Room
Updated: Aug 16
Medical Office Suite with Conference Room

6510 S Western Ave Unit 213, Oklahoma City, OK 73139

$3,000/Mo
2,800 sqft
Approximately 2,800 SF of medical office space
More than 10 rooms with reception area and conference room
Multiple restrooms and a breakroom
Parking for over 25 cars
Easy access to I‑240, I‑35, and I‑44
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Move-In Ready Office Suites
Move-In Ready Office Suites

1409 NW 122nd Street Unit: Suite A, Oklahoma City, OK 73114

$2,500/Mo
1,550 sqft

Two professionally designed office suites are available, each with a reception area, private offices, restrooms, and break room.

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Medical Office Building with Ample Parking
Medical Office Building with Ample Parking

937 SW 89th St, Oklahoma City, OK 73139

$16 SF/Yr
8,530 sqft

Three-suite medical office building with ample parking, strong signage, and two currently vacant built-out suites.

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1,300 - 6,500 SF of Retail Space Available in Oklahoma City, OK 73128
1,300 - 6,500 SF of Retail Space Available in Oklahoma City, OK 73128

1600 S Morgan Rd, Oklahoma City, OK 73128

$14 SF/Yr
1,300 sqft

Growing Neighborhood Retail Center

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Medical Office with X-Ray Room
Medical Office with X-Ray Room

4525 S. Klein Avenue, Oklahoma City, OK 73109

$3,750/Mo

The office includes clinical rooms, administrative offices, staff workspace, and a breakroom.

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Office Space Near Tinker AFB
Office Space Near Tinker AFB

3404 South Douglas Boulevard, Oklahoma City, OK 73150

$32 SF/Yr
12,000 sqft

Office space for rent near I-40 and Douglas Blvd.

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Secured-Entry Office and Medical Space
Secured-Entry Office and Medical Space

6300 NW Expressway, Oklahoma City, OK 73132

Contact for pricing
3,393 sqft

Tastefully updated office or medical suite with secured entry and frontage facing NW Expressway.

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Parkway Medical Building Office Space
Parkway Medical Building Office Space

3500 Northwest 56th Street, Oklahoma City, OK 73112

$23.50 SF/Yr
25,186 sqft

Two-story medical building with prime location and unparalleled access.

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Renovated Stand-Alone Office Building
Renovated Stand-Alone Office Building

2033 Heritage Park Dr, Oklahoma City, OK 73120

Contact for pricing
5,300 sqft

O-2-zoned property with multiple rooms, in-floor plumbing, and flexibility for professional, medical, research, or childcare uses.

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Medical Office Suite with X-Ray
Medical Office Suite with X-Ray

810 SW 89th Street, Oklahoma City, OK 73139

$16 SF/Yr

Former medical suite available with an X-ray room and treatment offices in a retail shopping center environment.

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Medical Office Space with Clear Span
Medical Office Space with Clear Span

12312 Market Dr, Oklahoma City, OK 73114

Contact for pricing
2,702 sqft

New construction medical/professional office space with clear-span design and flexible floor planning.

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Medical Office Space with Frontage Signage
Medical Office Space with Frontage Signage

8811 E Reno Ave, Oklahoma City, OK 73110

Contact for pricing
2,456 sqft

Medical office space with available frontage signage, maintained landscaping, and ample parking in Oklahoma City.

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Strip Mall With Medical Suite
Strip Mall With Medical Suite

1317 Southeast 44th Street, Oklahoma City, OK 73129

$14 SF/Yr

Retail center near a highway exit includes a completed medical suite and additional spaces for retail and service users.

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Medical Office Space with Reception
Medical Office Space with Reception

2820 Linda Ln, Oklahoma City, OK 73115

Contact for pricing
2,039 sqft

Built-out reception, waiting, administrative, and support areas suit office or soft medical use.

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Medical Office Space
Medical Office Space

5611 MOSTELLER DR, Oklahoma City, OK 73112

Contact for pricing
3,405 sqft

Medical office space is available for lease within a commercial property built in 1974.

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Medical Office Space Available
Medical Office Space Available

4215 N. Classen Boulevard, Oklahoma City, OK 73118

$14 SF/Yr

Medical office space with exam rooms and reception area.

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Medical Office Space
Medical Office Space

8516 S Portland Ave, Oklahoma City, OK 73159

Contact for pricing
5,971 sqft

Newly built clinical suites offer a ready-to-occupy setting with on-site parking.

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Versatile Office Space with Warehouse
Versatile Office Space with Warehouse

2800 S Glenn Ave, Oklahoma City, OK

Contact for pricing
4,761 sqft 0.61 AC lot

Office space with warehouse, suitable for medical or co-working use.

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Remodeled Medical Office Space
Remodeled Medical Office Space

4127 NW 122nd St, Oklahoma City, OK 73120

Contact for pricing
1,788 sqft

Recently updated space offers flexible planning with an open-concept area and signage along 122nd St.

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Multi-Floor Medical Office Space
Multi-Floor Medical Office Space

3110 SW 89th, Oklahoma City, OK 73159

$28 SF/Yr

Move-in-ready medical space with multiple floor plan options and ample parking.

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Medical Office Space with Exam Rooms
Medical Office Space with Exam Rooms

12516 N May Ave, Oklahoma City, OK 73120

$17.50 SF/Yr

C-3 zoning permits retail, office, and service uses.

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Built-Out Medical Clinic
Built-Out Medical Clinic

13900 Quailbrook Dr, Oklahoma City, OK 73134

$17 SF/Yr

Eight exam rooms, treatment space, private offices, and multiple restrooms support clinical operations.

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Open-Plan Retail Office Sublease
Open-Plan Retail Office Sublease

101 NE 82nd St, Oklahoma City, OK 73114

$23 SF/Yr

Sublease space delivered as open plan in an up-and-coming mixed-use development at 101 NE 82nd.

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Oklahoma City, OK Medical Office Space Lease Rates & Market Statistics

Browse 39 Medical Office Space listings for lease in Oklahoma City, OK on Realmo, a commercial real estate marketplace serving the Oklahoma City area. The current inventory totals 118,585 square feet of properties — an average of ~3,050 SF per listing.

Asking lease rates for Medical Office Space in Oklahoma City start at $8.73 SF/Yr, average $18.28 SF/Yr, and reach $32 SF/Yr at the top of the market. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $18.28 SF/Yr is 7% below the Oklahoma state average of $19.67 SF/Yr.

Medical Office Space listings make up 11% of the 358 Office Spaces currently for lease in Oklahoma City, with asking rates in line with the citywide Office Spaces average. Also worth a look for tenants weighing alternatives: Office Units (229 listings) and Office buildings (94 listings) elsewhere in the Oklahoma City market.

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