New York City, NY Medical Office Space for Rent & Lease

Updated: Jun 28

Storefront with Full Basement

60-06 Fresh Pond Road, Maspeth N Y, Ny, NY 11378

$4,500/Mo

2,470 sqft 0.04 AC lot

1,235 sq' storefront on Fresh Pond Road
High ceilings with open floor plan and waiting area
Three separate rooms support varied interior layouts
Newly renovated bathroom
Full‑length basement provides storage space

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Updated: Aug 3

First-Floor Medical Office Space

23 W 73rd Street #101 Room 4, New York (, Manhattan, NY 10023

$3,600/Mo

Approximately 553 SF total, including a 236 SF private office and 317 SF common area
First‑floor location positioned off the lobby
Shared waiting area and two shared bathrooms
Configured as a private psychiatrist’s office
Immediate possession with negotiable lease term

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Medical Office Space with Two Bathrooms

120-08 131 Street, New York, NY 11420

$4,999/Mo

Flexible multi-room layout with open, treatment, private office, and support areas for professional service operations.

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Medical Office Condo with Exam Rooms

198 Canal St 303, New York, NY 10013

$6,500/Mo

1,847 sqft

Five-room clinical layout with reception, storage, and a private bathroom.

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Medical Office Suite with Exam Rooms

198 Canal Street, New York (, Manhattan, NY 10013

$6,500/Mo

Configured for medical or professional practice with reception, storage, and a private bathroom.

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Medical Office Suite with Exam Rooms

139 Centre St 506, New York, NY 10013

$4,700/Mo

1,023 sqft

Configured for clinical use with sink hookups, a pantry, and a private half bathroom.

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Medical Office Build-to-Spec Space

47-01 Queens Boulevard, New York, NY 11104

$45 SF/Yr

5,181 sqft

Medical office space with ADA elevators and ADA-compliant bathrooms, configured for build-out to practice specifications.

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Medical Office Suite

160 East 56th Street, New York, NY 10022

$65 SF/Yr

3,875 sqft

Medical suite with plumbing, 220V outlets, and natural light, with immediate possession available.

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Turn-Key Medical Office in Gramercy

7 Lexington Avenue, New York, NY 10010

$3,500/Mo

700 sqft

Medical office space for lease in Gramercy Park neighborhood.

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Renovated Second-Floor Office

134 W 32nd St, New York, NY 10016

$5,500/Mo

1,700 sqft

Newly renovated second-floor office space with two half bathrooms and two included parking spaces.

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Boutique Office/Medical Building Near Park

250 West 57th Street, New York, NY 10107

$65 SF/Yr

5,300 sqft

16-story office/medical building near Central Park and Carnegie Hall.

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Midtown Building with Private Lobby

133 West 52nd Street, New York, NY 10019

$65 SF/Yr

12,789 sqft

55,000 sq ft vacant building ideal for healthcare, education.

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Lenox Hill Medical Office Space

20 East 68th Street, New York, NY 10065

$6,050/Mo

854 sqft

Professional/medical office for lease in Lenox Hill, Manhattan.

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First-Floor Medical Office Suite

23 West 73rd Street #101 Room 4, New York, NY 10023

$3,600/Mo

Private psychiatrist office with shared waiting area and two shared bathrooms.

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Office Suite with Two Rooms

7 Chatham Sq 202, New York, NY 10038

$2,300/Mo

Neat two-room office suite inside an elevator building with 24-hour doorman service.

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Medical Office Suite Above CVS

324 West 125th Street, New York, NY 10027

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6,780 sqft

Second-floor corner suite with elevator access above CVS and high-capacity electrical service for power-intensive medical uses.

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Flexible Office Units

197 3rd Ave, New York, NY 10003

Contact for pricing

3,108 sqft

Office space supports medical, community, daycare, and education uses with flexible division options and an onsite parking garage.

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Medical Office Suite at Transit Hub

185 Greenwich Street, New York, NY 10007

Contact for pricing

2,606 sqft

West Concourse Level 2 suite with 41+ feet of frontage along a high-traffic pedestrian corridor in a major downtown retail complex.

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Medical Office Space with Exam Rooms

250 W 57th St, New York, NY 10019

Contact for pricing

3,022 sqft

Medical office faces 57th Street and includes four exam rooms, an x-ray room, reception, and two private restrooms.

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Transit-Connected Medical Office Space

175 Greenwich St, New York, NY 10006

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1,684 sqft

West Concourse suite positioned along a pedestrian corridor connecting office, rail, subway, and ferry destinations.

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Flexible Office Space

C14-3370 Prince Street, New York, NY 11354

$2,500/Mo

Flexible office space available for lease in Flushing’s commercial district, suitable for professional, medical, or service use.

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Flexible Office Suite

C13-3370 Prince Street, New York, NY 11354

$2,500/Mo

Flexible office space available for lease in Flushing’s commercial district.

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Class-A Medical Office Building

110 E 60th St, New York, NY 10022

Contact for pricing

58,511 sqft

Prebuilt suites and medical infrastructure support Article 28 users.

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Built-Out Medical Office Space

159 E 30th St, New York, NY 10016

Contact for pricing

1,100 sqft

Second-floor and lower-level availability with a dedicated entrance from Third Avenue.

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New York City, NY Medical Office Space Lease Rates & Market Statistics

Browse 112 Medical Office Space listings for lease in New York City, NY on Realmo, a commercial real estate marketplace serving the New York City area. The current inventory totals 401,463 square feet of properties — an average of ~3,600 SF per listing.

Medical Office Space lease rates in New York City range from $21.86 SF/Yr at the entry level to $85.01 SF/Yr at the top of the market, averaging $51.84 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $51.84 SF/Yr, the local average runs 50% above New York's state average of $34.45 SF/Yr.

Medical Office Space listings make up 7% of the 1,506 Office Spaces currently for lease in New York City, with asking rates in line with the citywide Office Spaces average. Also worth a look for tenants weighing alternatives: Office Units (880 listings) and Office buildings (533 listings) elsewhere in the New York City market.