Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Medical Space
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Clay County, FL Medical Office Space for Lease

    List
    Map
    Miami, FL Jacksonville, FL Tampa, FL
    17 results
    Shell Office Space Available
    $22,344
    11,172 SF

    Shell Office Space Available

    1811 BLANDING Boulevard, Middleburg, FL 32068

    Shell office space with flexible suite sizes in Middleburg, FL.

    • Flexible suite sizes available, ranging from +/-5,259 SF to +/-11,172 SF.
    • Shell office space allows for custom layout design.
    • High visibility location on Blanding Blvd.
    • Convenient access to Orange Park, Middleburg, and Jacksonville's Westside.
    • Suitable for medical or professional users.
    Updated: Mar 24
    View details
    Updated Medical Office in Orange
    $2,500 /Mo
    1,444 SF

    Updated Medical Office in Orange

    2140 KINGSLEY Avenue, Orange Park, FL 32073

    Updated medical office space near HCA Florida Orange Park Hospital.

    • Prime location in the Medical Arts Center of Orange Park, near HCA Florida Orange Park Hospital.
    • Updated interior with fresh paint, modern hardware, and new baseboards.
    • Functional layout with reception/waiting area, business office, flex room, kitchenette, and three exam rooms.
    • CAM, taxes, and insurance included in lease.
    • Brick construction and ample parking.
    Updated: Nov 17, 2025
    View details
    Retail Hub at Plantation Crossing
    Contact for pricing

    Retail Hub at Plantation Crossing

    Retail, medical, restaurant, and service spaces for lease.

    1782 Blanding Boulevard, Middleburg, FL 32068
    View details
    Retail Hub at Plantation Crossing
    Contact for pricing
    64,808 SF

    Retail Hub at Plantation Crossing

    Retail, medical, restaurant, and service spaces available in Middleburg, FL.

    1782 Blanding Boulevard, Middleburg, FL 32068
    View details
    Single Story Office Building
    Contact for pricing
    17,563 SF

    Single Story Office Building

    Single story office building for lease near I-295.

    560 Wells Road, Orange Park, FL 32073
    View details
    Class A Medical Office Space
    Contact for pricing
    6,612 SF

    Class A Medical Office Space

    New medical office building with high parking ratio.

    1847 Kingsley Ave, Orange Park, FL
    View details
    Medical Building in Medical Row
    Contact for pricing
    4,579 SF

    Medical Building in Medical Row

    Freestanding medical building in the heart of Medical Row.

    1605 Kingsley Avenue, Orange Park, FL 32073
    View details
    Fleming Island Medical Office Space
    $22 SF/Yr
    12,088 SF

    Fleming Island Medical Office Space

    Class A medical office buildings in a growing community.

    4575 US 17 Fleming Island, Orange Park, FL
    View details
    Medical Office Space Available
    Contact for pricing
    30,000 SF

    Medical Office Space Available

    Prime location near hospital hub, customizable layout up to 30,000SF.

    1716 Blanding Blvd, Middleburg, FL
    View details
    Move-In Ready Medical Office Space
    Contact for pricing
    1,170 SF

    Move-In Ready Medical Office Space

    Well-maintained commercial space suitable for medical or professional uses.

    3180 County Rd 220, Middleburg, FL 32068
    View details
    Move-in Ready Office Space
    Contact for pricing
    2,704 SF

    Move-in Ready Office Space

    Office space available in high-demand Orange Park location.

    1409 Kingsley Ave, Orange Park, FL 32073
    View details
    Medical Office Space For Rent
    Contact for pricing
    8,740 SF

    Medical Office Space For Rent

    Move-in ready medical office space near Hwy 17.

    1681 Eagle Harbor Parkway, Fleming Island, FL
    View details
    Move-in Ready Medical Suites Available
    Contact for pricing
    2,200 SF

    Move-in Ready Medical Suites Available

    Medical suites available for lease in Fleming Island.

    1679 Eagle Harbor Parkway, Fleming Island, FL
    View details
    Move-in Ready Medical Space
    Contact for pricing
    4,620 SF

    Move-in Ready Medical Space

    Medical space for rent in Fleming Island medical campus.

    1675 Eagle Harbor Pkwy, Fleming Island, FL
    View details
    Medical Office Space For Rent
    $18 SF/Yr
    1,364 SF

    Medical Office Space For Rent

    Office space available in a dense medical corridor.

    2020 Kingsley Ave, Orange Park, FL
    View details
    Orange Park Medical/Professional Office
    Contact for pricing

    Orange Park Medical/Professional Office

    Second generation medical/professional office space in Orange Park, Florida.

    1329 Kingsley Ave, Orange Park, FL 32073
    View details
    Medical Office Space For Lease
    Contact for pricing

    Medical Office Space For Lease

    Medical office space available for lease.

    400 College Dr, Middleburg, FL 32068
    View details
    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 17 Active listings in Clay County, FL, we suggest exploring alternatives. Similar 10 Properties for Sales.

    Explore Similar Spaces for Sale in Clay County, FL

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Orange Park Commercial Property For Sale
    $975,000
    9,650 SF

    Orange Park Commercial Property For Sale

    Commercial property in high-traffic area suitable for various applications.

    1017 BLANDING Boulevard, Orange Park, FL 32065
    View details
    Orange Park Medical Office Investment
    $465,000
    2,280 SF

    Orange Park Medical Office Investment

    Medical office near Orange Park Medical Center, leased under contract.

    1555 KINGSLEY Avenue, Orange Park, FL 32073
    View details
    Medical Facility in Orange Park
    $1,199,000
    3,408 SF

    Medical Facility in Orange Park

    Equipped medical facility or business location in Orange Park, Florida.

    1906 DEBARRY Avenue, Orange Park, FL 32073
    View details
    Middleburg Commercial Investment Opportunity
    $1,200,000
    12,500 SF

    Middleburg Commercial Investment Opportunity

    Flexible commercial space ideal for investors or owner-users.

    430 College Drive, Middleburg, FL 32068
    View details
    Blanding Boulevard Commercial Property
    $975,000

    Blanding Boulevard Commercial Property

    Mixed-use retail property on Blanding Blvd with conversion potential.

    1017 Blanding Boulevard, Orange Park, FL 32065
    View details
    Professional Office Building For Sale
    $295,500
    1,421 SF

    Professional Office Building For Sale

    Professional office building with eight rooms in Green Cove Springs.

    625 OAK Street, Green Cove Springs, FL 32043
    View details
    Blanding Boulevard Mixed-Use Retail
    $975,000
    9,650 SF

    Blanding Boulevard Mixed-Use Retail

    Commercial property in high-traffic area, suitable for various applications.

    1017 Blanding Boulevard, Orange Park, FL 32065
    View details

    Clay County, FL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Clay County, FL with 17 listings featured on our commercial real estate exchange. The current inventory includes 484,735,680 square feet of properties with an estimated lease value of $58 SF/Yr.

    Estimated lease rates for Medical Office Space in Clay County, FL begin at $18 SF/Yr, with an average of $19 SF/Yr and extend to $20 SF/Yr.
    List
    Map

    Medical Office Space by market

    Browse Medical Office Space for Lease Near Clay, FL

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!