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Temecula, CA Medical Office Space for Lease

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8 results
Professional Medical Office Building For Rent
$1.75 SF/Yr
22,013 SF

Professional Medical Office Building For Rent

28999 Old Town Front St. |, Temecula, CA 92590

Well-maintained, two-story medical/professional office building with recent renovations.

  • Excellent access to Old Town Temecula and I‑15 via Temecula Pkwy Interchange.
  • Recently renovated common areas with high‑end LVT flooring and new landscaping.
  • Well‑maintained 2‑story professional & medical office building.
  • Flexible floor plans conducive to both medical & professional office users.
  • Elevator served.
Updated: Sep 25, 2025
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Temecula Office Space Available
$2 SF/Yr

Temecula Office Space Available

27555 Ynez Rd. |, Temecula, CA 92591

Office space for rent in Temecula, California.

  • Medical space available, perfect for your practice.
  • Suite 201 offers 1,923 SF.
  • Availability starting 10/1/2025.
  • Lease rates start at $2.75/SF.
  • Minimum 5 year lease term.
Updated: Sep 10, 2025
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Rancho California Medical Plaza
$1.95 SF/Yr
45,661 SF

Rancho California Medical Plaza

Medical and office spaces available for lease in Temecula, CA.

29645 Rancho California Rd. |, Temecula, CA 92591
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Temecula Office and Medical Suites
$1.80 SF/Yr
21,328 SF

Temecula Office and Medical Suites

Professional office and medical suites available for lease in Temecula.

27403 Ynez Rd. |, Temecula, CA 92591
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Premium Professional Office Space Available
Contact for pricing
37,621 SF

Premium Professional Office Space Available

High-image office space in Temecula, near Temecula Valley Hospital.

44045 Margarita Rd, Temecula, CA 92592
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Temecula Medical Center Office Space
Contact for pricing
57,600 SF

Temecula Medical Center Office Space

Medical office space for lease in Temecula, California.

27699 Jefferson Ave, Temecula, CA 92590
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Temecula Office/Medical Space Available
Contact for pricing
2,768 SF

Temecula Office/Medical Space Available

Professional office suites available for lease in Temecula, California.

43920 Margarita Road Suite B, Temecula, CA 92592
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Medical Office Space For Rent
$33 SF/Yr
1,800 SF

Medical Office Space For Rent

Turn-key medical office suite available across from Promenade Mall.

41238 Margarita Road, Suite 105, Temecula, CA 92590
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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 8 Active listings in Temecula, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space Available
Contact for pricing

Medical Office Space Available

Class A medical office space for lease or sale.

25470 Medical Center Drive, Murrieta, CA 92562
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Medical/Professional Office Suite For Rent
$1.59 SF/Yr
1,000 SF

Medical/Professional Office Suite For Rent

Medical or professional office suite available for rent.

933-937 Vale Terrace Dr, Vista, CA
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Medical/Professional Office Suites Available
$1.25 SF/Yr
1,000 SF

Medical/Professional Office Suites Available

Medical/professional office suites for lease with flexible layouts.

840-856 Townsite Dr, Vista, CA
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Premier Medical Facility Under Development
Contact for pricing
20,800 SF

Premier Medical Facility Under Development

Premium Murrieta medical office space with freeway visibility.

25130 Hancock Ave, Murrieta, CA 92562
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Explore Similar Spaces for Sale in Temecula, CA

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Prime Development Site in Temecula
$950,000
233,482.00 Acres

Prime Development Site in Temecula

5.36-acre corner lot ideal for medical, office, or institutional development.

0 Winchester Rd, Temecula, CA 92591
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Temecula Office/Medical Suites For Sale
$630,420
4,204 SF

Temecula Office/Medical Suites For Sale

Office and medical suites available near Promenade Mall and I-15.

41619 Margarita Rd. Suite 101 & 102, Temecula, CA 92591
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Dental/Medical Suite & Office Space
$1,751,860
4,204 SF

Dental/Medical Suite & Office Space

4,204 SF dental/medical suite and professional office for sale.

41619 Margarita Rd Suites 101 & 102, Temecula, CA 92591
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Grand Junction Commercial Land Lease
$9,656 /Mo

Grand Junction Commercial Land Lease

0.74 acre commercial land for lease in Grand Junction.

Highway 6&50, Grand Junction, CO 81505
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Grand Junction Commercial Land Opportunity
$17,728 /Mo

Grand Junction Commercial Land Opportunity

1.36 acre commercial land for lease in Grand Junction.

Sanford Drive, Grand Junction, CO 81505
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El Paso Commercial Land Lease
$3,600 /Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905
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Highway 72 Corner Lot
$6,500 /Mo
1,875 SF

Highway 72 Corner Lot

1.6 acre commercial lot for rent on Highway 72.

30472 Highway 72, Madison, AL 35756
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Temecula, CA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Temecula, CA with 8 listings featured on our commercial real estate exchange. The current inventory includes 0 square feet of properties with an estimated lease value of $7 SF/Yr.

Estimated lease rates for Medical Office Space in Temecula, CA begin at $1.75 SF/Yr, with an average of $1.96 SF/Yr and extend to $2 SF/Yr.
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