Medical Space

Temecula, CA Medical Office Space for Lease

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Temecula Office/Medical Space Available
Updated: Oct 4, 2025
Temecula Office/Medical Space Available

43920 Margarita Road Suite B, Temecula, CA 92592

$23.40 SF/Yr
2,768 sqft
Prime location on corner of Margarita Road and De Portola Road with easy access to I‑15.
Suitable for Office or Medical Use.
Ample parking with a ratio of 4:1,000 plus reciprocal parking agreements.
Architecturally designed professional office space.
Within walking distance to shopping, dining, and Temecula Valley Hospital.
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Temecula Professional and Medical Office
Updated: Mar 12
Temecula Professional and Medical Office

27349 Jefferson Ave, Temecula, CA 92590

Contact for pricing
36,474 sqft
Prime location with immediate access to Interstate 15 and proximity to The Promenade regional shopping center.
Move‑in ready suites suitable for professional, medical, or dental use.
Attractive architecture with high‑quality interior finishes and a landscaped courtyard garden.
Efficient layouts with no core or load factor.
Historically high occupancy and consistent lease performance.
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Temecula Office Space Available
Temecula Office Space Available

27555 Ynez Rd. |, Temecula, CA 92591

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72 sqft

Office space for rent in Temecula, California.

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Temecula Office and Medical Suites
Temecula Office and Medical Suites

27403 Ynez Rd. |, Temecula, CA 92591

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21,328 sqft

Professional office and medical suites available for lease in Temecula.

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Temecula Medical Center Office Space
Temecula Medical Center Office Space

27699 Jefferson Ave, Temecula, CA 92590

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57,600 sqft

Medical office space for lease in Temecula, California.

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Rancho California Medical Plaza
Rancho California Medical Plaza

29645 Rancho California Rd. |, Temecula, CA 92591

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45,661 sqft

Medical and office spaces available for lease in Temecula, CA.

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Medical Office Space For Rent
Medical Office Space For Rent

41238 Margarita Road, Suite 105, Temecula, CA 92590

$33 SF/Yr
1,800 sqft

Turn-key medical office suite available across from Promenade Mall.

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Medical Office Suite For Lease
Medical Office Suite For Lease

31565 Rancho Pueblo, Suite 102B, Temecula, CA 92592

$30 SF/Yr
2,439 sqft

Class A medical office suite available for lease.

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Medical Office Space Available
Medical Office Space Available

44274 George Cushman Court, Temecula, CA 92592

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32,471 SF medical office near Temecula Valley Hospital.

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Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 9 Active listings in Temecula, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical/Office Space for Lease
Medical/Office Space for Lease

25485 Medical Center Dr., Murrieta, CA 92562

Contact for pricing
5,464 sqft

Medical and office space available for lease.

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Medical/Professional Office Suite For Rent
Medical/Professional Office Suite For Rent

933-937 Vale Terrace Dr, Vista, CA

Contact for pricing
1,000 sqft

Medical or professional office suite available for rent.

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Medical Office Space Available
Medical Office Space Available

25467 Medical Center Drive, Murrieta, CA 92562

Contact for pricing

High-end medical office space for lease, attractive TI packages.

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Medical/Professional Office Suites Available
Medical/Professional Office Suites Available

840-856 Townsite Dr, Vista, CA

Contact for pricing
1,000 sqft

Medical/professional office suites for lease with flexible layouts.

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Similar Spaces for Sale in Temecula, CA

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Prime Development Site in Temecula
Prime Development Site in Temecula

Winchester Rd, Temecula, CA 92591

$950,000
5.36 AC lot

5.36-acre corner lot ideal for medical, office, or institutional development.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land for Long-Term Lease
Commercial Land for Long-Term Lease

5538 E Paisano Drive, El Paso, TX 79905

$5,950/Mo

Lease a C4-zoned lot with easy interstate access, suited for a range of business and professional uses.

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Office Development Land For Lease
Office Development Land For Lease

1323 Strawfloor Drive, Jonesboro, AR 72401

Contact for pricing
4,000 sqft

2.43 acres for office development with build-to-suit opportunity.

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Corner Lot on Highway 72
Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo
1,875 sqft

1.7 acre corner lot zoned for commercial, medical, residential.

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Prime Lexington Outlot Opportunity
Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

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Temecula, CA Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Temecula, CA with 9 listings featured on our commercial real estate exchange. The current inventory includes 7,007 square feet of properties with an estimated lease value of $86.40 SF/Yr.

Estimated lease rates for Medical Office Space in Temecula, CA begin at $23.40 SF/Yr, with an average of $28.80 SF/Yr and extend to $33 SF/Yr.
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