Greenville, NC Medical centers for Lease & Rent: Medical Buildings Near You

Updated: Apr 27

Medical Office Building

905 Johns Hopkins Drive, Greenville, NC 27834

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20,458 sqft 4.35 AC lot

20,458 SF medical office building built in 1989 on a 4.35‑acre site in Greenville, NC.
Adjacent to ECU Health Medical Center and the Brody School of Medicine.
Fully leased to ECU Physicians with State of North Carolina rent‑backed credit (AA-).
Lease provides 2% annual rent escalations through Feb. 2028.
Projected 2026 gross rental income of $465,243.78 and estimated operating expenses of $107,973.12 for NOI of $357,270.66.

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Updated: Jun 25

Renovated Medical Office Building

2450 Emerald Place, Greenville, NC 27834

$22 SF/Yr

Fully renovated in 2026 stand‑alone medical building
6,019 SF medical building with 11 exam rooms and a large reception/lobby area
Includes 6 offices in addition to exam room and reception space
Built in 2002
Located in Greenville’s medical district, near ECU Health Hospital campus

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 6 Potential Opportunities for your consideration. Besides 2 Active listings in Greenville, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Medical centers for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Renovated Medical Office with Exam Rooms

610 N Jefferson Avenue, Goldsboro, NC 27530

$4,000/Mo

2,184 sqft 0.93 AC lot

Flexible professional layout with reception, private offices, patient areas, and parking access from two streets.

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Renovated Medical Office Space

610 N Jefferson Ave, Goldsboro, NC 27530

$4,000/Mo

2,184 sqft

Medical office layout with exam rooms, reception, private offices, bathrooms, and a newly paved parking lot.

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Medical Outpatient and R&D Building

4225 Macon Pond Road, Raleigh, NC 27607

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62,246 sqft

State-of-the-art Class A medical and R&D space available.

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Medical Plaza at Rex

4414 Lake Boone Trail, Raleigh, NC 27607

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103,500 sqft

Class A medical office building on Rex Hospital campus.

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Greenville, NC Medical centers Lease Rates & Market Statistics

Browse 2 Medical centers for lease in Greenville, NC on Realmo, a commercial real estate marketplace serving the Greenville area. The current inventory totals 20,458 square feet of properties.

Medical centers lease rates in Greenville range from $22 SF/Yr at the entry level to $22 SF/Yr at the top of the market, averaging $22 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $22 SF/Yr, the local average runs 8% above North Carolina's state average of $20.43 SF/Yr.

Greenville accounts for 100% of the 2 medical centers currently available across Pitt County. Medical centers are one of the more limited space types in Greenville, with just 2 listings currently available — a scarcity worth factoring into lease negotiations.