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300 4th Street San Francisco, CA 94107

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For Lease
$38 SF/Yr

18,000 SF office space in the Pioneer Building.

Type:Office
Property size:
18,000 SF
Added:
Jan 27, 2026
Days on Market:
63
Last Refresh:
Mar 25 at 9:12 pm

Property Features for 300 4th Street

General Information

Standard status
Active
Size
18,000 SF
Property subtype
Office

Spaces For Lease

at 300 4th Street Contact us

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Listing Contact
Jake Levinson

Listing agent Jake Levinson License #CalDRE #02021931

Listing office Ground Matrix

Listing date Jan 27, 2026

Source Groundmatrix

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of Ground Matrix


Overview

Pioneer Building Office Space

The Pioneer Building, located at 300 4th Street, offers a rare opportunity for a single tenant. Previously used as a museum, the 18,000 square-foot property features advanced HVAC and security systems. This office property is positioned directly across from Yerba Buena and the Moscone Center and is ADA accessible. The annual rental rate is $38 per square foot, NNN.
Location Intelligence

Current Use by Public Records

Society of California Pioneers Historical Society AltSchool High School

Suggested Use

Restaurant Real Estate Agency Spa & Massage Center Hair Salon Dental Office Nail Salon Food Market Law Firm Grocery & Convenience Store Daycare Center

Zoning and permitted uses should be independently verified with local authorities.

Location Insight

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City
San Francisco
County
San Mateo
State
California
Longitude
-122.401
Latitude
37.7817

FAQs

What type of property is this?
Office building - 18,000 SF office space in the Pioneer Building.
Where is this office building located?
The property is located at 300 4th Street San Francisco, CA.
What is the lease rate?
The lease rate is $38 SF/Yr.
What are key features of this property?
This property features: Rare opportunity for a single tenant user in the Pioneer Building.; Located directly across from Yerba Buena & Moscone Center.; Top‑of‑the‑line HVAC and Security systems (previously used as a museum).
More about this property
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