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Pioneer Building Office Space

300 4th Street San Francisco, CA 94107

300 4th Street, San Francisco, CA, 94107
$57,000/Mo
For Lease
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$38 SF/Yr $57,000/Mo (calc)

18,000 SF office space in the Pioneer Building.

Property Size18,000 SF
AddedJan 27
Days on Market168
Last RefreshApr 5 at 8:55 pm

Property Features for 300 4th Street

General Information

Standard status
Active
Size
18,000 SF
Property subtype
Office

Spaces For Lease

at 300 4th Street Contact us

Listing office Ground Matrix

Listing date Jan 27, 2026

Source Groundmatrix

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of Ground Matrix


Investment Insights

Based on property information with market context.

The Pioneer Building, located at 300 4th Street, offers a rare opportunity for a single tenant. Previously used as a museum, the 18,000 square-foot property features advanced HVAC and security systems. This office property is positioned directly across from Yerba Buena and the Moscone Center and is ADA accessible. The annual rental rate is $38 per square foot, NNN.

Key Highlights

  • Rare opportunity for a single tenant user in the Pioneer Building.
  • Located directly across from Yerba Buena & Moscone Center.
  • Top‑of‑the‑line HVAC and Security systems (previously used as a museum).

Property Analytics

Property Profile Location Intelligence

Current Use by Public Records

Society of California Pioneers Historical Society AltSchool High School

Suggested Use

Veterinary Clinic Tanning Salon Buffet Clothing & Fashion Store Pet Grooming Service Nursing Home Adult Day Care Fish Market Clothing & Fashion Store Butcher

Zoning and permitted uses should be independently verified with local authorities.

FAQs

What type of property is this?
Office building - 18,000 SF office space in the Pioneer Building.
Where is this office building located?
The property is located at 300 4th Street San Francisco, CA.
What is the lease rate?
The lease rate is $38 SF/Yr.
What are key features of this property?
This property features: Rare opportunity for a single tenant user in the Pioneer Building.; Located directly across from Yerba Buena & Moscone Center.; Top‑of‑the‑line HVAC and Security systems (previously used as a museum).
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