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For lease
Office Units
NY
Buffalo
14214
2290 Main Street

First-Floor Office and Medical Space

2290 Main Street, Buffalo, NY 14214

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For Lease

$2,400/Mo $6 SF/Yr (calc)

COMMERCIAL - Buffalo, NY

Property size:

4,620 SF

Lot size:

0.13 Acres

HighLights

High visibility location on busy Main Street corridor.
Flexible layout suitable for office, medical, or retail use.
Welcoming entrance lobby for a positive first impression.
Multiple private office rooms.
Easy transition with minimal modifications needed.
Well‑maintained, professional setting.

We can help!

Listing Contact

Thejan Kodituwakku

For Lease

$2,400/Mo $6 SF/Yr (calc)

COMMERCIAL - Buffalo, NY

Property size:

4,620 SF

Lot size:

0.13 Acres

Added:: Feb 28, 2026
Days on Market:: 108
Last Refresh:: Jun 16 at 12:06 pm

Property Features for 2290 Main Street

General Information

Property type: Commercial Lease
Property subtype: Other
Zoning: N-3
Parking: 1
Standard status: Active
APN: 140200-089-500-0003-010-000
Size: 4,620 SF
Lot size: 0.13 Acres

Utilities

Sewer type: Public Sewer
Heating system: Forced Air, Natural Gas
Water source: Public

Building Details

Year built: 1950
Floors in Building: 3
Roof type: Flat

We can help!

Listing Contact

Thejan Kodituwakku

Listing agent Thejan Kodituwakku License #10401342241

Listing office Keller Williams Realty WNY 5500 Main St. Ste. 108, Williamsville, NY

Listing date Feb 28, 2026

MLS# B1660444

Copyright © 2026 New York State Alliance of MLSs, LLC. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

HighLights

High visibility location on busy Main Street corridor.
Flexible layout suitable for office, medical, or retail use.
Welcoming entrance lobby for a positive first impression.
Multiple private office rooms.
Easy transition with minimal modifications needed.
Well‑maintained, professional setting.

Overview

First-floor commercial suite designed for professional use, featuring a welcoming entrance lobby and multiple private office rooms. The interior configuration is set up to support businesses that need both a reception-oriented entry and dedicated working areas, with the flexibility to accommodate medical, dental, professional office, or retail operations based on the existing layout.

The property is located on the Main Street corridor in Buffalo, NY, positioned for strong day-to-day visibility and street presence. The space is described as clean, functional, and well maintained, offering a practical setting for teams that want to serve clients from a prominent frontage location.

For tenants seeking a ready-to-work arrangement, the combination of a client-facing lobby and private offices can streamline day-to-day operations. The layout is particularly aligned with medical and dental use, while remaining workable for professional office users or retail operators looking for an established, first-floor setting with direct customer access.

Property Profile Location Intelligence

Current Use by Public Records

Blackley John C ... Physician Mathew E. Sendker, ... Physician Crinzi Alexander R ... Physician Leonard Patti L ... Physician Matthew E. Shepherd Physician

Suggested Use

Location Insight

Map
Local Demand

City: Buffalo
County: Erie
State: New York
Longitude: -78.847492
Latitude: 42.932077

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For lease
Office Units
NY
Buffalo
14214
2290 Main Street

What type of property is this?

Office units - First-floor commercial space with a client lobby and multiple private offices suited for medical, dental, or professional use.

Where is this office units located?

The property is located at 2290 Main Street Buffalo, NY.

What is the lease rate?

The lease rate is $2,400 /Mo.

What are key features of this property?

This property features: High visibility location on busy Main Street corridor.; Flexible layout suitable for office, medical, or retail use.; Welcoming entrance lobby for a positive first impression.

2290 Main Street, Buffalo, NY 14214

COMMERCIAL - Buffalo, NY

Property Features for 2290 Main Street

General Information

Utilities

Building Details

We can help!

HighLights

Overview

Current Use by Public Records

Suggested Use

Location Insight

Nearby Similar for Lease

Medical Office with Exam Rooms

Renovated Storefront Office Space

Restaurant Building at South Park

Third-Floor Office Suite

Elmwood Avenue Professional Office Space

Elmwood Village Private Office Space

Turn-Key Restaurant and Warehouse

Warehouse with Retail and Office Space

Multi-Suite Office Building

Retail Space in Buffalo, NY

Retail Space in Buffalo, NY

Renovated Commercial Space in Buffalo

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