2240 North Douglas Street, Florence, SC 29501

Spaces For Lease

at 2240 North Douglas Street Contact us

Listing agent Andrew Chaplin III License #SC 94480

Listing office Palmetto Commercial Show Phone

Listing date May 29, 2026

Source Crexi

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of Palmetto Commercial

Report an issue

---

Overview

This office building is situated within a well-established professional business park and is designed to serve office-focused tenants. The property includes on-site parking with 28 front spaces, plus additional parking available at the rear of the building.

The building is positioned for visibility from I-95 and provides convenient access to both I-95 and I-20. It is centrally positioned for easy access to all areas of Florence, and the surrounding area includes a mix of professional offices, industrial users, and commercial services.

With its office-oriented setting, strong interstate visibility, and straightforward vehicle access and parking, this property is a practical fit for companies seeking an office location in a stable, active commercial environment within the Florence area.

Suggested Use

Restaurant Building Supply Big Box & Wholesale Store Hair Salon Auto Repair Shop Nail Salon Pharmacy Auto Parts Store Hotel & Motel Department Store

Zoning and permitted uses should be independently verified with local authorities.

Location Insight

• Map
• Local Demand

City

Florence

County

Florence

State

South Carolina

Longitude

-79.7866413

Latitude

34.2387272

Nearby Similar for Lease

• 

  $2,500/Mo

  2,304 SF

  Two-Unit Retail Conversion Opportunity

  Two storefront units with restaurant conversion-ready features on a high-traffic corridor near I-95.

  225 W Lucas St, Florence, SC 29501

  View Details
• 

  $2,900/Mo

  3,100 SF

  Office Building with Private Offices

  Functional office layout with hardwood floors, meeting room, kitchen, basement storage, and on-site parking for client-facing operations.

  720 S Coit St, Florence, SC 29501-5113

  View Details
• 

  $5,000/Mo

  11,390 SF

  Industrial Flex Building with Bay Doors

  Flexible industrial space with multiple bay doors and front office area for vehicle, equipment, and service operations.

  374 Darlington St., Florence, SC 29501-2504

  View Details
• 

  $18,134/Mo

  95,840 SF

  Retail Spaces in CrossRoads Center

  Retail spaces available in high-traffic Florence commercial corridor.

  2522, 2524, 2528 David H McLeod Blvd, Florence, SC 29501

  View Details
• 

  Contact for pricing

  4,800 SF

  Florence Flex/Industrial Property for Lease

  4,800 SF flex/industrial building with drive-through capability and outside storage.

  3731 East National Cemetery Road, Florence, SC 29506

  View Details
• 

  Contact for pricing

  2,700 SF

  Restaurant Space with Drive-Thru

  2,700 SF restaurant space with existing drive-thru.

  1104 Pamplico Highway, Florence, SC 29505

  View Details
• 

  $22 SF/Yr

  2,800 SF

  Retail Space in Regional Destination

  Retail space available in premier shopping center, built in 2015.

  112-120 Woody Jones Blvd, Florence, SC

  View Details
• 

  $1,950/Mo

  2,000 SF

  Commercial Office Space For Rent

  Office space available in Shoppes at Celebration shopping center.

  2527 S Cashua Dr, Florence, SC 29501

  View Details
• 

  Contact for pricing

  Warehouse with Showroom and Yard

  Single tenant building with showroom, warehouse, and fenced yard.

  511 Irby Street, Florence, SC 29501

  View Details
• 

  $25 SF/Yr

  2,400 SF

  Retail Space in Regional Destination

  Retail spaces available in premier shopping destination, built in 2015.

  104 Woody Jones Blvd, Florence, SC

  View Details
• 

  $22 SF/Yr

  7,145 SF

  Modern Office Space For Rent

  7,145 SF customizable office space in Florence, SC.

  2701 Alex Lee Blvd, Florence, SC 29506

  View Details
• 

  $90 SF/Yr

  36,360 SF

  Florence Warehouse in West End

  Warehouse in Florence's West End District, near major retailers.

  2295 Hoffmeyer Rd, Florence, SC 29501

  View Details

FAQs

What type of property is this?

Office building - Office building in a professional business park with visibility from I-95 and convenient access to I-20.

Where is this office building located?

The property is located at 2240 North Douglas Street Florence, SC.

What are key features of this property?

This property features: Office building in a professional business park with visibility from I‑95; Convenient access to both I‑95 and I‑20; On‑site parking includes 28 front spaces, with additional parking at the rear