Saint Clair Shores, MI Commercial Real Estate for Sale

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Medical Office Building For Sale
Updated: Nov 21, 2025
Medical Office Building For Sale

St Clair Shores, MI 48081

$2,375,000
15,566 sqft
100% occupied medical office building
Two tenant building with 2 units
15,566 SF building
Located on Harper Avenue
Between 10 and 11 Mile Road
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26210 Harper Avenue, St. Clair Shores, MI 48081

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Flex Office with Drive-Through Bay
Updated: Jun 2
Flex Office with Drive-Through Bay

25530 Little Mack Avenue, Saint Clair Shores, MI 48081

$475,000
2,400 sqft 0.10 AC lot
Office layout includes reception area, executive office, small office, and restroom
Bay doors provide drive‑through capability with a curb cut directly onto Little Mack Ave
Forced‑air heating with public water; year built 1987
Roof includes shingle and flat roofing
Shop area features a floor drain
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Corner Commercial Development Site
Corner Commercial Development Site

24101 Jefferson Avenue, Saint Clair Shores, MI 48080

$1,950,000
60,113 sqft 1.54 AC lot

Commercially zoned corner site with approximately 325 feet of Jefferson Avenue frontage and a second parcel included for redevelopment.

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Hair Salon Retail Building
Hair Salon Retail Building

25835-25837 Jefferson Avenue, Saint Clair Shores, MI 48081

$175,000
1,098 sqft

Well-maintained storefront building currently operating as a hair salon, offering a functional layout for retail, office, or service use.

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Zoned B-3 Commercial Building
Zoned B-3 Commercial Building

St Clair Shores, MI 48081

$650,000
5,627 sqft

5,627 SF commercial building with two vacant units, zoned B-3 for retail, office, and service use.

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Freestanding Retail/Office Building
Freestanding Retail/Office Building

22230 Harper Avenue, Saint Clair Shores, MI 48080

$140,000
1,000 sqft 0.32 AC lot

Freestanding building at a lighted hard-corner intersection with onsite parking, suited for retail, office, or service use.

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Commercial Corner Redevelopment Land
Commercial Corner Redevelopment Land

24101 Jefferson Avenue, Saint Clair Shores, MI 48080

$1,950,000
1.54 AC lot

Corner commercial land with significant Jefferson Avenue frontage and strong street presence for sale or ground lease.

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Two-Building Office Package
Two-Building Office Package

St Clair Shores, MI 48081

$699,000
4,770 sqft

Two-building commercial office package with a renovated multi-tenant building, recent HVAC and roof upgrades, and shared parking.

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Corner Retail/Warehouse with Overhead Door
Corner Retail/Warehouse with Overhead Door

22300 Harper Ave, St Clair Shores, MI 48080

$550,000
4,896 sqft

4,896 SF corner parcel offers retail/warehouse space with an overhead door and dedicated on-site parking.

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Automotive 3-Bay Repair Shop
Automotive 3-Bay Repair Shop

22900 Greater Mack Avenue, Saint Clair Shores, MI 48080

$329,000
2,000 sqft

Nearly 2,000-sf three-bay shop with power bay doors, equipment, and 35+ parking spaces in downtown St. Clair Shores.

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Three-Unit Strip Center
Three-Unit Strip Center

St Clair Shores, MI 48080

$175,000
6,216 sqft 0.70 AC lot

Three-unit strip center on a 0.7-acre lot with two currently vacant units.

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Move-In Ready Retail Suite
Move-In Ready Retail Suite

26801 Harper Ave, Saint Clair Shores, MI 48081

$175,000
645 sqft

Move-in ready retail space with a new roof, updated paint, lighting, ceiling grid, and two parking spaces.

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Renovated Industrial Warehouse
Renovated Industrial Warehouse

20520 Stephens Street, St Clair Shores, MI 48080

$545,800
4,700 sqft 0.28 AC lot

Newly renovated warehouse with fenced yard, two restrooms, and two bay doors, plus extensive recent capital improvements.

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Renovated Industrial Warehouse
Renovated Industrial Warehouse

St Clair Shores, MI 48080

$545,900
5,000 sqft 0.28 AC lot

Newly renovated industrial building offers two restroom facilities, two loading bays, and a fenced, secured yard.

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Well-Maintained Office/Medical Building For Sale
Well-Maintained Office/Medical Building For Sale

St Clair Shores, MI 48081

$1,199,000
5,805 sqft

Fully occupied office/medical building near I-696 and I-94.

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Turnkey Office Suite with Reception
Turnkey Office Suite with Reception

28501 Little Mack Avenue Unit SourceFi, Saint Clair Shores, MI 48081

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5,396 sqft

Move-in ready suite with reception, private office, back office, bathroom, and covered vestibule entry in a professional building.

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Professionally Managed Office Complex
Professionally Managed Office Complex

St Clair Shores, MI 48081

$695,000
4,533 sqft

Professionally owned and managed office complex for sale.

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Office Building with Parking
Office Building with Parking

St Clair Shores, MI 48080

$550,000
6,810 sqft

Office building for sale offering up to 3,300 SF of available leasing space with ample parking.

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Multi-Unit Retail Storefront Building
Multi-Unit Retail Storefront Building

25835-25837 Jefferson Avenue, St Clair Shores, MI 48081

$200,000
1,098 sqft

Well-maintained storefront building currently operating as a hair salon, with a layout that can support retail, office, or service uses.

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Veterinary Practice and Building For Sale
Veterinary Practice and Building For Sale

St Clair Shores, MI 48081

$650,000
0.25 AC lot

Thriving veterinary practice and building in prime location for sale.

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Assisted Living Retirement Facility
Assisted Living Retirement Facility

31601 Harper Avenue, St Clair Shores, MI 48082

$2,750,000
18,000 sqft

Licensed assisted living and memory care center with two fully furnished buildings containing tenant rooms and caregiver housing.

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Professional Building with Suites Available
Professional Building with Suites Available

21603-21611 E 11 Mile Rd, Saint Clair Shores, MI 48081

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7,430 sqft

Professional building with office and medical suites, excellent exposure.

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Professional Office Building For Sale
Professional Office Building For Sale

25319 Little Mack Ave, Saint Clair Shores, MI 48081

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7,048 sqft

Professional office building in Saint Clair Shores, suitable for various uses.

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Professionally Managed Office Complex
Professionally Managed Office Complex

Saint Clair Shores, MI 48081

Contact for pricing
4,533 sqft

Office complex with prominent signage and on-site property management.

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Saint Clair Shores, MI Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Saint Clair Shores, MI, showcased through 41 active listings on our real estate platform. These investment opportunities span a total of 371,664 square feet of properties for sale, with an estimated market value of $21,098,500.

Sale prices for business properties in Saint Clair Shores, MI start at $140,000, averaging $843,940, and reaching up to $2,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 58K
Population Growth (5Y) -2.5%
Median Household Income $73,721
College Educated 39.0%

High-Yield Neighborhoods for Investment

Identify Saint Clair Shores submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
48081 $130K
48080 $1M
48082 $1.5M

Taxes & Financing

Tax Rate (average for all types) 4.58%
Property Tax per SF $54.62 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Macomb County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Macomb County

Residential Income

Property Size Breakdown

The majority of commercial real estate listings in Saint Clair Shores fall within the 10,000 to 25,000 square foot range.

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