Saint Clair Shores, MI Commercial Real Estate for Sale

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Eastpointe, MI Roseville, MI Harper Woods, MI
26 properties
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Medical Office Building For Sale
Updated: Nov 21, 2025
Medical Office Building For Sale

St Clair Shores, MI 48081

$2,375,000
15,566 sqft
100% occupied medical office building
Two tenant building with 2 units
15,566 SF building
Located on Harper Avenue
Between 10 and 11 Mile Road
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This listing looks promising.

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26210 Harper Avenue, St. Clair Shores, MI 48081

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Flex Office with Drive-Through Bay
Updated: Jun 2
Flex Office with Drive-Through Bay

25530 Little Mack Avenue, Saint Clair Shores, MI 48081

$475,000
2,400 sqft · 0.10 AC lot
Office layout includes reception area, executive office, small office, and restroom
Bay doors provide drive‑through capability with a curb cut directly onto Little Mack Ave
Forced‑air heating with public water; year built 1987
Roof includes shingle and flat roofing
Shop area features a floor drain
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Corner Commercial Development Site
Corner Commercial Development Site

24101 Jefferson Avenue, Saint Clair Shores, MI 48080

$1,950,000
60,113 sqft · 1.54 AC lot

Commercially zoned corner site with approximately 325 feet of Jefferson Avenue frontage and a second parcel included for redevelopment.

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Freestanding Corner Retail Office
Freestanding Corner Retail Office

22230 Harper Avenue, Saint Clair Shores, MI 48080

$140,000
1,000 sqft · 0.32 AC lot

Freestanding building on a lighted intersection with onsite parking and convenient access to major nearby routes.

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Hair Salon Retail Building
Hair Salon Retail Building

25835-25837 Jefferson Avenue, Saint Clair Shores, MI 48081

$175,000
1,098 sqft

Well-maintained storefront building currently operating as a hair salon, offering a functional layout for retail, office, or service use.

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Corner Commercial Redevelopment Land
Corner Commercial Redevelopment Land

24101 Jefferson Avenue, Saint Clair Shores, MI 48080

$1,950,000
1.54 AC lot

Commercially zoned corner lot with about 325 feet of Jefferson Avenue frontage and multiple access points.

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Saint Clair Shores Bank Building
Saint Clair Shores Bank Building

21800 Greater Mack Ave, Saint Clair Shores, MI 48080

$1,945,600
6,372 sqft · 1.55 AC lot

Single tenant bank building with drive-thru in Saint Clair Shores.

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Turnkey Retail Space on Harper
Turnkey Retail Space on Harper

St Clair Shores, MI 48081

$550,000
4,026 sqft

Immaculate, move-in-ready retail space in St. Clair Shores.

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Veterinary Practice and Building For Sale
Veterinary Practice and Building For Sale

St Clair Shores, MI 48081

$650,000
0.25 AC lot

Thriving veterinary practice and building in prime location for sale.

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Freestanding Corner Retail Office
Freestanding Corner Retail Office

St Clair Shores, MI 48080

$140,000

Freestanding building on a hard corner with onsite parking and strong intersection visibility for retail, office, or service use.

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St. Clair Shores Redevelopment Opportunity
St. Clair Shores Redevelopment Opportunity

St Clair Shores, MI 48080

$1,950,000

Commercial land for sale along the Nautical Mile.

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Auto Repair and Office Building
Auto Repair and Office Building

26305 Harper Ave, St Clair Shores, MI 48081

Contact for pricing
12,406 sqft · 1.18 AC lot

Auto repair facility and office/storage building on 1.18 acres.

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Office Building with Private Offices
Office Building with Private Offices

St Clair Shores, MI 48081

$499,900
0.28 AC lot

Office building featuring 15 private offices and ample parking.

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Saint Clair Shores Office Building
Saint Clair Shores Office Building

26200 Harper Ave, Saint Clair Shores, MI

$2,375,000
15,566 sqft · 0.98 AC lot

15,566 SF office building in Saint Clair Shores.

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Freestanding Office Building on Harper
Freestanding Office Building on Harper

22708 Harper, Saint Clair Shores, MI

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8,138 sqft · 0.17 AC lot

Highly visible office building with ample parking and recent improvements.

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Well-Maintained Office/Medical Building For Sale
Well-Maintained Office/Medical Building For Sale

St Clair Shores, MI 48081

$1,199,000
5,805 sqft

Fully occupied office/medical building near I-696 and I-94.

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Professional Building with Suites Available
Professional Building with Suites Available

21603-21611 E 11 Mile Rd, Saint Clair Shores, MI 48081

Contact for pricing
7,430 sqft

Professional building with office and medical suites, excellent exposure.

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Professionally Managed Office Complex
Professionally Managed Office Complex

St Clair Shores, MI 48081

$695,000
4,533 sqft

Professionally owned and managed office complex for sale.

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Professionally Managed Office Complex
Professionally Managed Office Complex

Saint Clair Shores, MI 48081

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4,533 sqft

Office complex with prominent signage and on-site property management.

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Professional Office Building For Sale
Professional Office Building For Sale

25319 Little Mack Ave, Saint Clair Shores, MI 48081

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7,048 sqft

Professional office building in Saint Clair Shores, suitable for various uses.

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Class A Medical Building Suite
Class A Medical Building Suite

20225-20229 E 9 Mile, Saint Clair Shores, MI 48080

Contact for pricing
22,000 sqft

Medical suite in Class A building, ideal for specialist.

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Saint Clair Shores Office Building
Saint Clair Shores Office Building

St Clair Shores, MI 48080

$320,000
2,200 sqft

Well-maintained 2,200 SF office building in the Nautical Mile.

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Retail Space For Sale
Retail Space For Sale

St Clair Shores, MI 48080

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1,600 sqft

Retail space available for purchase.

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Industrial Land I-94 Frontage
Industrial Land I-94 Frontage

14 Mile, Saint Clair Shores, MI

$1,500,000
8.71 AC lot

8.71 acres of light industrial land with high visibility.

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Saint Clair Shores, MI Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Saint Clair Shores, MI, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 149,056 square feet of properties for sale, with an estimated market value of $16,713,000.

Sale prices for business properties in Saint Clair Shores, MI start at $140,000, averaging $928,500, and reaching up to $2,375,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 58K
Population Growth (5Y) -2.5%
Median Household Income $73,721
College Educated 39.0%

High-Yield Neighborhoods for Investment

Identify Saint Clair Shores submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
48081 $130K
48080 $1M
48082 $1.5M

Taxes & Financing

Tax Rate (average for all types) 4.58%
Property Tax per SF $54.62 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Macomb County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Macomb County

Residential Income

Property Size Breakdown

The majority of commercial real estate listings in Saint Clair Shores fall within the 10,000 to 25,000 square foot range.

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