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South San Francisco Office/Lab Space
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180 Kimball Way & 442 Littlefield Ave, South San Francisco, CA 94080

Office and laboratory spaces in South San Francisco.

Space Size10,951 SF - 49,838 SF
Days on Market282

Property Features for 180 Kimball Way & 442 Littlefield Ave

General Information

Standard status Active
Size 10,951 SF - 49,838 SF
Property subtype LifeSciences

Spaces For Lease

at 180 Kimball Way & 442 Littlefield Ave Contact us

180 Kimball Way - 1st floor

Size
49,838 SF
Type
Flex
Availability
Available
Contact us

180 Kimball Way - 2nd floor

Size
10,951 SF
Type
Flex
Availability
Available
Contact us

442 Littlefield Ave - Full Building

Size
24,351 SF
Type
Flex
Availability
Available
Contact us
Listing Agency: CBRE | San Francisco
Listed By: Chris Jacobs · License #00900432
Source: Cbre
Added: Nov 22, 2025 Changed: Aug 25 Last Checked: Aug 30 at 2:08PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE | San Francisco

Investment Insights

Based on property information with market context.

Life Science Center offers office and laboratory spaces in South San Francisco. The property is surrounded by biotechnology and tech companies and is situated in a Bay Area setting. The property size is 85140 square feet.

Key Highlights

  • Prime location in South San Francisco, a hub for biotechnology and tech companies.
  • Office and laboratory spaces available.
  • Situated in a desirable Bay Area setting.

Property Analytics

Current Use

Office Units

Suggested Use

Top Pick Dental Office (Bike/Boat/Book/etc) Store Veterinary Clinic Locksmith Tattoo & Piercing Shop Restaurant

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

943
Businesses Nearby

Demographics for 94080, CA

66,592
Population
23,364
Households
2.9
Avg Household Size
40
Median Age
40%
College-Educated
86%
High-School Grad
10.2 sq mi
ZIP Area
6,529
Density / Sq Mi
$135,966
Median Household Income
$61,138
Median Earnings
$2,840
Median Rent
$1,159,500
Median Home Value

Market

Vacancy Rate% for Office in West region

11% 2019
14.1% 2020
15.5% 2021
17.2% 2022
19.9% 2023
21% 2024
20.8% 2025
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Questions? Ask Rey
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Frequently Asked Questions

What type of property is this?
Office units - Office and laboratory spaces in South San Francisco.
Where is this office units located?
The property is located at 180 Kimball Way & 442 Littlefield Ave South San Francisco, CA.
What are key features of this property?
This property features: Prime location in South San Francisco, a hub for biotechnology and tech companies.; Office and laboratory spaces available.; Situated in a desirable Bay Area setting.
More about this property
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