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Wytheville, VA Commercial Real Estate for Sale

19 results
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Downtown Wytheville Multi-Purpose Commercial Building
$399,000
4,949 SF

Downtown Wytheville Multi-Purpose Commercial Building

195 S 1St St, Wytheville, VA 24382

Two-story commercial building with income potential in downtown Wytheville.

  • Prime downtown location on a busy corner.
  • Multi‑purpose, two‑story building with existing tenants.
  • Over 2,000 SF of available space on the second floor.
  • Well‑maintained building with a history of successful businesses.
  • Additional income potential from existing tenants.
Updated: Feb 13
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Turnkey Storage Operation in Wytheville
$285,500
8,900 SF

Turnkey Storage Operation in Wytheville

2465 Grayson Tpke, Wytheville, VA 24382

Storage units, garage, and land with income potential.

  • Turnkey storage unit operation with income from multiple sources.
  • Significant income potential: currently $16,000 annually, with potential to reach $36,500.
  • Ample land available for future expansion.
  • Four‑bay garage offers additional income‑generating opportunity.
  • Convenient location just south of Wytheville along a major thoroughfare.
Updated: Mar 5
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Prime Commercial Land I-81 Corridor
$399,000
8.63 Acres

Prime Commercial Land I-81 Corridor

8.63 acres of commercial land in Wytheville, Virginia.

8.63 Ac Cv Rd, Wytheville, VA 24382
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Wytheville Land Development Opportunity
$169,900
1.85 Acres

Wytheville Land Development Opportunity

1.847 acres in Wytheville, VA, zoned for diverse development.

Peppers Ferry Rd, Wytheville, VA 24382
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Wytheville Land with B-2 Zoning
$55,000
0.70 Acres

Wytheville Land with B-2 Zoning

Vacant lot in Wytheville, VA, zoned B-2.

lot 2A & 2A1 W Main St, Wytheville, VA 24382
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Commercial Lot in Wytheville, VA
$274,000
1.36 Acres

Commercial Lot in Wytheville, VA

Commercial lot with high visibility near I-81 and local amenities.

N 4Th St, Wytheville, VA 24382
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Industrial-Zoned Property in Wytheville, VA
$299,000
2.58 Acres

Industrial-Zoned Property in Wytheville, VA

2.58-acre industrial-zoned property near industrial park in Wytheville, VA.

N 4Th St, Wytheville, VA 24382
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Wytheville Commercial Land For Sale
$2,600,000
35.00 Acres

Wytheville Commercial Land For Sale

35 acres of commercial land near the interstate.

Stafford Umberger Dr, Wytheville, VA 24382
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Expansive Land Parcel in Wytheville
$2,950,000
87.66 Acres

Expansive Land Parcel in Wytheville

87+ acre parcel ideal for commercial or residential development.

Community Blvd, Wytheville, VA 24382
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Commercial Lot Near Interstate Exit
$124,900
0.91 Acres

Commercial Lot Near Interstate Exit

Commercial lot near I-81 exit with high traffic volume.

Holston Rd, Wytheville, VA 24382
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Commercial Lot Near Interstate Exit
$124,900
39,630 SF

Commercial Lot Near Interstate Exit

Commercial land near I-81 exit with high traffic volume.

Holston Rd, Wytheville, VA 24382
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Historic Office Space in Wytheville
Contact for pricing

Historic Office Space in Wytheville

Furnished, move-in-ready office space in a recognizable historic building.

150 W Main St, Wytheville, VA 24382
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Commercial Property with Development Potential
$640,000
17.50 Acres

Commercial Property with Development Potential

17.5 acre commercial property with building and development opportunities.

135 Envision Dr, Wytheville, VA 24382
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Prime Wytheville Car Wash Business
$395,000
2,400 SF

Prime Wytheville Car Wash Business

Profitable Car Wash - High Visibility

425 Main St, Wytheville, VA 24382
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Prime Wytheville Restaurant Opportunity
$985,000
6,064 SF

Prime Wytheville Restaurant Opportunity

6,064 SF Restaurant, $985,000

190 Lithia Rd, Wytheville, VA 24382
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Prime Wytheville Commercial Land
$640,000

Prime Wytheville Commercial Land

17.5 Acres, Commercial Building, Views

135 Envision Dr, Wytheville, VA 24382
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Wytheville Commercial Building - High Visibility
$179,000
1.10 Acres

Wytheville Commercial Building - High Visibility

Prime Commercial Space, High Visibility, 5300 sq ft

610 Lee Hwy, Wytheville, VA 24382
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Prime Wytheville Retail Investment
$1,810,000
4,400 SF

Prime Wytheville Retail Investment

High-cap rate, corporate-guaranteed Mattress Firm

230 Commonwealth Dr, Wytheville, VA 24382
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Prime Commercial Land I-81/I-77
$1,700,000
44.57 Acres

Prime Commercial Land I-81/I-77

Unbeatable visibility and location at I-81 and I-77 interchange.

2484 E Lee Hwy, Wytheville, VA 24382
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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 19 Active Listings in Wytheville, VA

Wytheville, VA Commercial Real Estate Investment Opportunities Market Analysis

Explore 19 commercial real estate for sale in Wytheville, VA, showcased through 19 active listings on our real estate platform. These investment opportunities span a total of 8,818,679 square feet of properties for sale, with an estimated market value of $9,785,800.

Sale prices for business properties in Wytheville, VA start at $55,000, averaging $815,483, and reaching up to $2,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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