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    Wytheville, VA
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    Wytheville, VA Commercial Real Estate for Lease

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    Pulaski, VA Bluefield, VA Coral Gables, FL
    7 results
    Dominant Regional Retail Center Space
    Contact for pricing
    5,021 SF
    Dominant Regional Retail Center Space

    215-345 Commonwealth Dr, Wytheville, VA

    Regional retail center anchored by Walmart and Lowes.
    • Anchored by Walmart Supercenter and Lowes Home Improvement, driving significant customer traffic
    • Located at the busiest intersection in the area, off I‑81 (exit 70) and SR 21
    • High traffic counts: 31,000 VPD on I‑81 and 16,000 VPD on Hwy 21
    • Dominant regional retail center in Wytheville, VA, drawing from a 10‑mile radius
    • National tenants including Bealls, Dollar Tree, Petco, Pizza Hut and Subway
    Updated: Aug 4, 2025
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    Former Restaurant Space Available
    $216 SF/Yr
    6,064 SF
    Former Restaurant Space Available

    190 Lithia Rd, Wytheville, VA 24382

    Restaurant space for lease in high-traffic area.
    • High‑traffic location in the I‑81 / I‑77 Crossroads development corridor.
    • Large 6,064 SF building on 1.26 acres.
    • Favorable B zoning.
    • Wythe County Assessment of $1,312,800.
    • Former Bob Evans restaurant space.
    Updated: Feb 10, 2025
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    Retail Space in Lehy Plaza
    Contact for pricing
    18,900 SF
    Retail Space in Lehy Plaza

    Retail space available in Food Lion anchored Lehy Plaza.

    1370-1380 E Main St, Wytheville, VA

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    Retail Space in High-Traffic Center
    $26 SF/Yr
    Retail Space in High-Traffic Center

    End unit retail space in Starbucks-anchored center with high foot traffic.

    198 Commonwealth Dr, Wytheville, VA 24382

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    Renovated Shopping Center For Lease
    Contact for pricing
    1,385 SF
    Renovated Shopping Center For Lease

    99,745 SF renovated shopping center on 8.69 acres.

    205 Fairground Road, Wytheville, VA

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    Renovated Shopping Center For Lease
    Contact for pricing
    4,311 SF
    Renovated Shopping Center For Lease

    99,745 SF renovated shopping center on 8.69 acres.

    880 E Main St, Wytheville, VA

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    Renovated Shopping Center Space Available
    Contact for pricing
    1,400 SF
    Renovated Shopping Center Space Available

    99,745 SF renovated shopping center on 8.69 acres.

    235 Fairground Rd, Wytheville, VA

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    Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 7 Active listings in Wytheville, VA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 17 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space in New Development
    $20 SF/Yr
    1,867 SF
    Retail Space in New Development

    Retail space available in a grocery-anchored new development.

    1201 E Main St, Pulaski, VA

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    Retail Space Near Interstate I-77
    Contact for pricing
    1,920 SF
    Retail Space Near Interstate I-77

    Retail space available in neighborhood center adjacent to major retailers.

    1130 E Stuart Dr, Galax, VA

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    Showroom Suite in Pulaski Plaza
    $6 SF/Yr
    20,250 SF
    Showroom Suite in Pulaski Plaza

    Large showroom suite in busy shopping center with ample parking.

    1106-1200 E Main St, Pulaski, VA

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    Retail Space in Twin County
    Contact for pricing
    4,000 SF
    Retail Space in Twin County

    Retail space available in well-positioned shopping center.

    1081-1093 E Stuart Dr, Galax, VA

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    Similar Spaces for Sale in Wytheville, VA

    Consider Similar Space for Sale. We found 17 Spaces matching your search parameters.

    Commercial Property in Wytheville, VA
    $250,000
    3,360 SF
    Commercial Property in Wytheville, VA

    Income-producing commercial property with established tenants in a prime location.

    1330 W Ridge Street, Wytheville, VA 24382

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    Downtown Wytheville Multi-Purpose Commercial Building
    $399,000
    4,949 SF
    Downtown Wytheville Multi-Purpose Commercial Building

    Two-story commercial building with income potential in downtown Wytheville.

    195 S 1st Street, Wytheville, VA 24382

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    Wytheville Land Development Opportunity
    $169,900
    1.85 Acres
    Wytheville Land Development Opportunity

    1.847 acres in Wytheville, VA, zoned for diverse development.

    Peppers Ferry Road lot: 2, Wytheville, VA 24382

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    Commercial Lot in Wytheville, VA
    $199,000
    1.36 Acres
    Commercial Lot in Wytheville, VA

    Commercial lot with high visibility near I-81 and local amenities.

    1.36 AC N 4th St., Wytheville, VA 24382

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    Wytheville Commercial Property with Acreage
    $640,000
    6,000 SF
    Wytheville Commercial Property with Acreage

    Commercial property with building, doublewide, acreage, and mountain views.

    135 Envision Drive, Wytheville, VA 24382

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    Expansive Land Parcel in Wytheville
    $2,950,000
    87.66 Acres
    Expansive Land Parcel in Wytheville

    87+ acre parcel ideal for commercial or residential development.

    Community Blvd lot: 131, Wytheville, VA 24382

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    Industrial-Zoned Property in Wytheville, VA
    $299,000
    2.58 Acres
    Industrial-Zoned Property in Wytheville, VA

    2.58-acre industrial-zoned property near industrial park in Wytheville, VA.

    N 4th Street, Wytheville, VA 24382

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    Wytheville Commercial Land For Sale
    $2,600,000
    35.00 Acres
    Wytheville Commercial Land For Sale

    35 acres of commercial land near the interstate.

    Stafford Umberger Drive, Wytheville, VA 24382

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    Recreational Land with Creek Access
    $365,000
    34.22 Acres
    Recreational Land with Creek Access

    Private 34-acre tract with open pasture, mature woodland, and direct Reed Creek access for outdoor use and potential build sites.

    Reed Creek Mill Road lot: 0, Wytheville, VA 24382

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    Wytheville Land with B-2 Zoning
    $55,000
    0.70 Acres
    Wytheville Land with B-2 Zoning

    Vacant lot in Wytheville, VA, zoned B-2.

    W Main Street lot: 2A & 2A1, Wytheville, VA 24382

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    Ground-Floor Historic Office Suite
    Contact for pricing
    Ground-Floor Historic Office Suite

    Move-in-ready furnished office with kitchenette, restrooms, and flexible layout for professional use.

    150 W Main Street, Wytheville, VA 24382

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    Owner-Occupant Office with Parking
    $170,000
    1,080 SF
    Owner-Occupant Office with Parking

    Office property in Wytheville with its own parking lot and storage building, suited for owner-occupants or investors.

    170 S 16th St, Wytheville, VA 24382

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    Mattress Firm Retail Investment Opportunity
    $1,900,000
    4,400 SF
    Mattress Firm Retail Investment Opportunity

    Freestanding Mattress Firm at I-81 & I-77 crossroads.

    230 Commonwealth Dr, Wytheville, VA 24382

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    Income-Producing Commercial Property For Sale
    $250,000
    3,360 SF
    Income-Producing Commercial Property For Sale

    Income-producing property with established tenants in a prime commercial corridor.

    1330 W Ridge Street, Wytheville, VA 24382

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    Hotel with Modern Amenities
    $3,500,000
    37,184 SF
    Hotel with Modern Amenities

    Hotel featuring complimentary breakfast, Wi-Fi, and pet-friendly accommodations.

    140 Lithia Rd, Wytheville, VA 24382

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    Retail Space on 1.26 Acres
    $795,000
    6,064 SF
    Retail Space on 1.26 Acres

    6,064 SF retail space in I-81/I-77 Crossroads development.

    190 Lithia Rd, Wytheville, VA 24382

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    17.5 Acres Commercial Land Opportunity
    $640,000
    2,500 SF
    17.5 Acres Commercial Land Opportunity

    17.5 acres with commercial building and mountain views.

    135 Envision Drive, Wytheville, VA 24382

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    Wytheville, VA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Wytheville, VA with 7 listings featured on our commercial real estate exchange. The current inventory includes 6,064 square feet of properties with an estimated lease value of $216 SF/Yr.

    Estimated lease rates for Commercial real estate in Wytheville, VA begin at $216 SF/Yr, with an average of $216 SF/Yr and extend to $216 SF/Yr.
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