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Mission Bay Class-A Office Space
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455 Mission Bay Boulevard South, San Francisco, CA 94158

Class-A office space in amenity-rich Mission Bay neighborhood.

Space SizeContact for details
Property Size24,002 SF
Days on Market260

Property Features for 455 Mission Bay Boulevard South

General Information

Standard status Active
Size 24,002 SF
Property subtype Office
Listing Agency:
Listed By: James Bennett · License #00869074
Source: Cbre
Added: Nov 22, 2025 Changed: Jul 6 Last Checked: Aug 9 at 1:09PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of James Bennett

Investment Insights

Based on property information with market context.

This Class-A office building offers 24,002 rentable square feet. The building features robust MEP infrastructure to support ancillary R&D uses. FF&E is available. The location provides convenient access to Highway 280 and 101. A dedicated Mission Bay shuttle provides transportation to BART, Caltrain, and Ferries. The parking ratio is 1.39/1,000. The property is in a prime location adjacent to UCSF and the Third Street light rail, within an amenity-rich neighborhood. The LED is December 31, 2029.

Key Highlights

  • Prime location adjacent to UCSF and Third Street light rail.
  • Purpose‑Built Class‑A office building with robust MEP infrastructure.
  • Dedicated Mission Bay shuttle to BART, Caltrain and Ferries.

Property Analytics

Current Use

Nektar Therapeutics Factory Alexandria Real Estate Real Estate Agency DNAlite Therapeutics, Inc Corporate Office Xcell Biosciences Corporate Office Wild Horse Productions Film Production

Suggested Use

Top Pick HVAC Service Grocery & Convenience Store Pet Grooming Service Veterinary Clinic Barber Shop Tanning Salon

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

5,896
Businesses Nearby

Demographics for 94158, CA

11,327
Population
5,300
Households
2.1
Avg Household Size
33
Median Age
77%
College-Educated
94%
High-School Grad
0.6 sq mi
ZIP Area
18,878
Density / Sq Mi
$184,294
Median Household Income
$120,408
Median Earnings
$3,316
Median Rent
$1,501,100
Median Home Value

Market

Lease Benchmarks for San Francisco, CA

$36.85 /SF/Yr
Avg Asking Price
$1.14–$57 /SF/Yr
Price Range
29,162 SF
Avg Space Size

Vacancy Rate% for Office in San Francisco, CA

5.4% 2019
15.8% 2020
18.5% 2021
24.1% 2022
32.5% 2023
34.2% 2024
33.1% 2025
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Frequently Asked Questions

What type of property is this?
Office building - Class-A office space in amenity-rich Mission Bay neighborhood.
Where is this office building located?
The property is located at 455 Mission Bay Boulevard South San Francisco, CA.
What are key features of this property?
This property features: Prime location adjacent to UCSF and Third Street light rail.; Purpose‑Built Class‑A office building with robust MEP infrastructure.; Dedicated Mission Bay shuttle to BART, Caltrain and Ferries.
More about this property
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