Listing Agency: CBRE | San Francisco D***@cbre.com Show Phone

Listed By: Dino Perazzo · License #01220613 Show Phone

Source: Cbre

Added: Nov 22, 2025 Changed: Aug 21 Last Checked: Aug 23 at 6:02AM

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Investment Insights

Based on property information with market context.

This Class A building, situated within the South San Francisco life science cluster, offers 175,720 square feet of space. The property benefits from direct access to Highway 101.

Key Highlights

• Class A life science building
• Prime location within South San Francisco life science cluster
• Direct access to Highway 101

Property Analytics

Property Profile

Current Use

Office buildings

Lease Details

NNN (Triple Net)

Lease Type

Location Intelligence

Trade Area within ½ mile

980

Businesses Nearby

Explore this area Business Placement

Demographics for 94080, CA

66,592

Population

23,364

Households

2.9

Avg Household Size

40

Median Age

40%

College-Educated

86%

High-School Grad

10.2 sq mi

ZIP Area

6,529

Density / Sq Mi

$135,966

Median Household Income

$61,138

Median Earnings

$2,840

Median Rent

$1,159,500

Median Home Value

Market

Vacancy Rate% for Office in West region

11% 2019

14.1% 2020

15.5% 2021

17.2% 2022

19.9% 2023

21% 2024

20.8% 2025

Questions? Ask Rey

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Frequently Asked Questions

What type of property is this?

Office building - Class A life science building in prime South San Francisco location.

Where is this office building located?

The property is located at One & Two Tower Place South San Francisco, CA.

What are key features of this property?

This property features: Class A life science building; Prime location within South San Francisco life science cluster; Direct access to Highway 101