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    Medina County, TX Commercial Real Estate for Sale

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    Houston, TX San Antonio, TX Dallas, TX
    56 listings
    Unrestricted Land Near San Antonio
    $2,700,000
    1,960 SF
    Unrestricted Land Near San Antonio

    3124 HWY 90 E, Castroville, TX 78009

    5.084 acres of unrestricted land ideal for investment.
    • 5.084 acres of unrestricted land ideal for investment, business, or residential use.
    • Located west of San Antonio in the rapidly growing area of Castroville.
    • Outside city limits of San Antonio, offering flexibility and fewer restrictions.
    • Excellent opportunity for long‑term value appreciation.
    • Suitable for investors, developers, or buyers seeking space and potential.
    Updated: Apr 13
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    Refrigerated Industrial Distribution Complex
    $1,500,000
    23,050 SF
    Refrigerated Industrial Distribution Complex

    568 Carter, Hondo, TX 78861

    Perimeter-fenced industrial site with insulated refrigerated space, loading access, and multiple purpose-built structures on four acres.
    • 3 buildings on a 4.0‑acre, perimeter‑fenced tract with gated, keypad access
    • 14,800+/- SF total: 10,000+/- SF insulated and refrigerated warehouse with 17+/- ton capacity
    • Main warehouse built in 1986 and expanded in 2004 and 2020, with a loading well
    • Free‑standing office building of 1,600+/- SF built in 2008
    • Equipment shed of 6,650+/- SF built in 2022
    Updated: Sep 23, 2025
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    Unrestricted Land in Castroville, TX
    $2,700,000
    2,432 SF
    Unrestricted Land in Castroville, TX

    5.077 acres of unrestricted land west of San Antonio.

    3100 HWY 90 E, Castroville, TX 78009

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    Natalia Horse Ranch with Amenities
    $650,900
    1,920 SF
    Natalia Horse Ranch with Amenities

    25.83-acre horse ranch with equestrian amenities near Natalia, Texas.

    18434 Fm 471, Natalia, TX 78059

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    Unrestricted Residential Acreage
    $250,000
    1,512 SF
    Unrestricted Residential Acreage

    Unrestricted 6-acre tract in residential zoning for flexible custom build and homestead use outside HOA limits.

    17272 Fm 463, Natalia, TX 78059

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    221 Acre Medina County Ranch
    $1,327,992
    221.33 Acres
    221 Acre Medina County Ranch

    Versatile South Texas ranch with hunting habitat and native pastureland.

    D Hanis, TX 78850

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    Natalia, TX Horse Ranch
    $410,000
    1,920 SF
    Natalia, TX Horse Ranch

    20.5-acre horse ranch with equestrian amenities near Natalia, TX.

    18434A Fm 471, Natalia, TX 78059

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    Country Homesite with Owner Financing
    $150,000
    2.80 Acres
    Country Homesite with Owner Financing

    A rural homesite on acreage in Natalia, TX, offering flexible use and owner financing options.

    19101 Fm 463, Lot 6r, Natalia, TX 78059

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    Agricultural & Hobby Farm Land
    $150,000
    2.50 Acres
    Agricultural & Hobby Farm Land

    A 2.5-acre parcel zoned OCL in Natalia, TX, suited for country living and livestock-compatible property use.

    19101 Fm 463, Natalia, TX 78059

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    Hondo, TX Mixed-Use Property
    $895,000
    4,806 SF
    Hondo, TX Mixed-Use Property

    Mixed-use property in Hondo, TX with retail and office.

    1115 19th St, Hondo, TX 78861

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    Hondo Commercial Property For Sale
    $1,500,000
    23,050 SF
    Hondo Commercial Property For Sale

    Versatile industrial property in Hondo, TX, near San Antonio.

    Hondo, TX 78861

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    Downtown Hondo Commercial Building
    $750,000
    7,500 SF
    Downtown Hondo Commercial Building

    Large commercial building in Hondo's central business district.

    1602 Avenue M, Hondo, TX 78861

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    Versatile Land in Medina County
    $650,000
    6.05 Acres
    Versatile Land in Medina County

    6.05 acres near LaCoste, TX, with multiple development possibilities.

    La Coste, TX 78039

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    Hill Country Acreage with Paved Road Access
    $250,000
    20.02 Acres
    Hill Country Acreage with Paved Road Access

    Privately positioned acreage in a gated ranch subdivision with electricity and fiber to the front and horses allowed.

    D Hanis, TX 78850

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    Versatile Land in Medina County
    $1,287,000
    26.83 Acres
    Versatile Land in Medina County

    26.83 acres near LaCoste, TX, with development potential.

    La Coste, TX 78039

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    Texas Hill Country Land
    $221,000
    10.00 Acres
    Texas Hill Country Land

    10 acres in Hondo, TX with hilltop views.

    100 County Road 242, Hondo, TX 78861

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    Residential Land Lot in Gated Community
    $125,000
    334,105 SF
    Residential Land Lot in Gated Community

    Hilltop residential homesite with cleared build area, oak trees, cul-de-sac setting, and long-distance views in a private ranch community.

    194 CRESCENT RDG, Hondo, TX 78861

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    11 Acres in Devine, TX
    $199,000
    479,160 SF
    11 Acres in Devine, TX

    Unrestricted 11-acre property perfect for building or investment.

    1083 County Road 6610, Devine, TX 78016

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    Expansive Land in Devine, TX
    $162,800
    8.30 Acres
    Expansive Land in Devine, TX

    8+ acres of unrestricted, fenced land in Devine ISD.

    County Road 664, Devine, TX 78016

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    5 Acres Near Devine, TX
    $149,500
    5.00 Acres
    5 Acres Near Devine, TX

    5+ acres of land near Devine, Texas, with minimal restrictions.

    County Road 671, Devine, TX 78016

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    Mico, Texas 10-Acre Land
    $144,000
    10.00 Acres
    Mico, Texas 10-Acre Land

    10 acres of gently rolling, tree-studded land in Mico, TX.

    COUNTY ROAD 2744 lot: 342, Mico, TX 78056

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    Standalone Medical Office Building
    $350,000
    1,800 SF
    Standalone Medical Office Building

    Move-in ready medical office with exam rooms, clinical sinks, and reception area for healthcare or professional use.

    200 West College Avenue, Devine, TX 78016

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    Large Acreage in Growing Corridor
    $2,697,000
    1,662 SF
    Large Acreage in Growing Corridor

    179.8 acre tract in high-growth West San Antonio corridor.

    1151 Co Rd 2615, Rio Medina, TX 78066

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    16+ Acres in Devine, TX
    $375,000
    1,680 SF
    16+ Acres in Devine, TX

    Expansive 16+ acre land with multiple improvements near Devine.

    179 PR 6624, Devine, TX 78016

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    Medina County, TX Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Medina County, TX, showcased through 56 active listings on our real estate platform. These investment opportunities span a total of 1,136,486 square feet of properties for sale, with an estimated market value of $24,132,643.

    Sale prices for business properties in Medina County, TX start at $199,000, averaging $1,096,938, and reaching up to $4,425,843 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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